Prof. Dipshikha Chakravortty's Lab
@DipaLab_IISc
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PI: Dipshikha Chakravortty (MCBL, IISc Bangalore). We study molecular pathogenesis of Salmonella in murine, nematode and plant systems.
Bangalore, India
Joined February 2021
Thanks you @biopatrika for covering our recent study by @KirtiPa21603835 and team ๐๐๐๐
#authorinterview Kirti Parmar @KirtiPa21603835 PhD with Prof. Dipshikha Chakravortty lab @DipaLab_IISc at @iiscbangalore talks about her work on "Antioxidant gene yqhD influences susceptibility of Salmonella to bile salts" #salmonella
https://t.co/fmIfg8zeE6 via @biopatrika
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Heartiest Congratulations to @Debapri57550341 and @anmolsingh82 for winning the Best Poster Award at the ASM Global Research Symposium on One Health and AMRโฅ๏ธโฅ๏ธ๐๐๐๐ Proud moment for DC Lab
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DC Lab @ ASM Global Research Symposium on One Health Approach to AMR ( IISc)๐๐๐๐
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Glad to share our latest publication in mSphere! Our study reveals how _Salmonellaโs_ aldehyde reductase YqhD influences its resilience to bile stress. Heartiest wishes to @KirtiPa21603835 and the team ๐๐ Link ๐
journals.asm.org
Foodborne pathogen Salmonella can tolerate high concentrations of bile and even survive the harsh environment of the gall bladder. This study is significant as it explores the role of a novel...
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Elated to share our new publication: We dissect intracellular formate regulation in Salmonella "A- motilityโtoโinvasion" switch, uncovering a metabolic cue controlling virulence. Link: https://t.co/KXgYEFM4f5 Congratulations to @Debapri57550341 and all other co-authors๐๐
journals.plos.org
Author summary The ability of Salmonella Typhimurium to modulate the expression of its virulence factors in response to diverse environmental cues has positioned it as a highly successful pathogen....
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We extend our heartiest congratulations and regards to Debapriya, Kirti, Anmol and Rhea for successfully giving their colloquium. All the best to the four of them๐๐โจโฅ๏ธ
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The endoplasmic reticulum (ER) of the host cell may play a role in helping Salmonella bacteria escape detection, IISc study shows. Read more: https://t.co/Taytu1gP9L
#IIScresearch
@DipaLab_IISc
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DC lab's first PhD colleague, Prof. Sandeep Eshwarappa who discovered the SCV division, is contributing to the major AX4 project with Water Bear (IISc Bengaluru strain) From Salmonella to tardigrades ๐ฎ๐ณ
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We all spent a great afternoon yesterday with some nice authentic North Indian Cuisine ๐๐๐ฅณ
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@umeshchopra17 Heartiest Congratulations ๐๐
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2009: Eswarappa et. al established the single bacterium in a vacuole concept. On cover art- Infection and Immunity(ASM). 2025: Chopra https://t.co/AJuUXYyDVT delineated the mechanism. On cover art mBio(ASM). Salmonella is never homeless as the home gets divided with Salmonella
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Syntaxin 7 in sync with Salmonella - working together for successful life--- Amazing Bacteria ๐๐ Our latest research article is online now.... Link:-
onlinelibrary.wiley.com
Salmonella Typhimurium hijacks the host Qa-SNARE syntaxin 7 (STX7) to manipulate endo-lysosomal trafficking and sustain intracellular survival. STX7 displays cellโtypeโspecific expression and...
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It was an immense pleasure to have young minds from Classes 4, 5 and 6 in our lab. They were amazed to visualise life under the microscope and explained how they aspire to cure diseases one day๐ฉ๐ปโ๐ฌ๐จ๐ปโ๐ฌ DC lab always looks forward to igniting, and inspiring young scientific minds๐จ๐ปโ๐ซ
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DC Lab team members - Rhea, Yogyata and Abhishek mentored students from Jawahar Navodaya Vidyalaya Bangalore - as a part of the "IISc Agastya SEP Program 2025" The young minds under the mentorship of my PhD students performed exciting experiments in our laboratory ๐จ๐ปโ๐ฌ๐ฉ๐ปโ๐ฌ๐๐
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Igniting young minds๐ฉ๐ปโ๐ฌ๐จ๐ปโ๐ฌ..... School children from various parts of the country being inspired by DC Lab at IISc Bangalore. #DCLab #Salmonella
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Glad to share that our latest review is online now. Check out the link below. Heartiest congratulations to the team๐๐๐ฅณ๐ฅณ https://t.co/rQV0q7dPJ9
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Endoplasmic reticulum facilitates the coordinated division of #Salmonella-containing vacuoles. New #mBio study by @umeshchopra17 @DipaLab_IISc. https://t.co/L6cQZHbHdU
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Heartiest congratulations to all the team members. We show the effect of SIRT1 and SIRT3 on mitochondrial function and host Salmonella pH balance during infection. Extending our regards to @ACSPublications for publishing our work๐๐๐๐ #Salmonella #DCLab
https://t.co/hKM6YKRpYM
pubs.acs.org
Mitochondria are important organelles that regulate energy homeostasis. Mitochondrial health and dynamics are crucial determinants of the outcome of several bacterial infections. SIRT3, a major...
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Extending our gratitude to @mbiojournal @ASMicrobiology for publishing our research. We would also like to thank the esteemed agencies- Department of Atomic Energy, Govt. of India, DST and TATA innovation Fellowship for funding our work.
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