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Tau Center Without Walls (CWOW) Profile
Tau Center Without Walls (CWOW)

@tauCWOW

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Using multiomics & functional genomics #CRISPR screens to study gene expression leading to novel therapeutic targets for treatment of #tauopathies

Joined May 2022
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@tauCWOW
Tau Center Without Walls (CWOW)
2 years
RT @MartinUCSF: Tenure-track faculty search of the @Ucsf_Biochem.Department is open for applications! . We are looking for creative, innov….
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@tauCWOW
Tau Center Without Walls (CWOW)
2 years
RT @MartinUCSF: Now out in @NatureSMB:. DELE1 oligomerization promotes integrated stress response activation . Work led by @_JieYang @Lande….
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@tauCWOW
Tau Center Without Walls (CWOW)
2 years
RT @bowles_lab: Have you seen our website yet?.#tau #newPI #newLab
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @MartinUCSF: Learning to control microglia using CRISPR. Thank you @NIH for supporting our work .(first author @DraegerNina, collaborati….
nih.gov
Researchers used CRISPR tools to identify genes controlling cells in the brain called microglia, which are involved in Alzheimer’s disease and other brain disorders.
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @SinaiGenetics: Multiple tenure-track or tenured faculty positions at the Assistant, Associate, or Full Professor levels in Computationa….
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @GeschwindLab: Our latest publication led by Yonatan Cooper identifying new dementia risk genes using MPRAs to screen noncoding GWAS var….
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science.org
High-throughput functional analysis reveals cell-type-specific regulatory networks that mediate genetic risk for dementia.
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @SinaiBrain: Just 2⃣ days left to submit your #MSNseminars applications! Senior postdocs in ALL fields related to #neuro are invited to….
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @MartinUCSF: Check out this great Tweetorial by first author @DraegerNina to learn more about our paper "A CRISPRi/a platform in iPSC-de….
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @MartinUCSF: Excited that we could contribute to this work led by ⁦@MarcoJost_⁩ & ⁦@JswLab⁩: . Maximizing CRISPRi efficacy and accessib….
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biorxiv.org
CRISPR interference (CRISPRi) enables programmable, reversible, and titratable repression of gene expression (knockdown) in mammalian cells. Initial CRISPRi-mediated genetic screens have showcased...
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
RT @SinaiGenetics: ✴️Open Postdoc Position✴️The Goate lab concentrates on identifying human genetic variants associated w/AD & dissecting t….
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
Projects led by our PIs will use multiomics & functional genomics #CRISPR screens to understand molecular & cellular differences in gene expression & cell function due to H1/H2 haplotype inversion leading to new therapeutic targets for treating tauopathies
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@tauCWOW
Tau Center Without Walls (CWOW)
3 years
#Tau CWOW is a multi-site, interdisciplinary center connecting multiple levels of function: genotype, chromatin structure, RNA expression & splicing, and protein & cell biological consequences to elucidate mechanisms of tauopathies, funded by @NINDSnews
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