David Strutt
@struttlab
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Cell and Developmental Biologist at the University of Sheffield.
Sheffield, UK
Joined January 2018
The Northern England Developmental Biology @_BSDB_ @Co_Biologists meeting takes place on July 10th in Sheffield. Register by May 31st - its gonna be cool 😎 (see the poster below for details)!
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📢We have a 3y postdoc position available in our interdisciplinary team @institut_curie #Paris Join us if you're interested in epithelial tissue morphogenesis using live imaging, quantitative biology & (opto)genetics. https://t.co/uNmshuk1YI Please RT!
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Postdoc position available in the Röper lab at the University of Cambridge! @PDN_Cambridge Join us and discover the role that control of cytoskeletal dynamics, crosstalk and cell adhesion play in the formation of the nephron tube in human renal organoids! https://t.co/NOGv80sceC
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Beautiful work, showing radial cell behaviours in #morphogenesis, similarly to my previous work @MRC_LMB in @katjaroeper lab. “Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding”
cell.com
Leybova et al. utilize live imaging and 3D reconstructions to uncover a radial pattern of cell fate, morphology, adhesion, and motility in developing hair follicle primordia. Radial patterning is...
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Our latest on planar polarity mechanisms. Painstaking work by Alexandre Carayon, investigating mechanisms of cell-scale polarisation in the fly wing. Enjoy it (if this is your thing)! @struttlab @UK_Wnt @MCB_Sheffield @DRN_Sheffield
Evidence for strong cell-scale signalling during planar polarisation in the Drosophila wing https://t.co/wJ3l0QmImj
#biorxiv_devbio
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Matakatsu and Fehon @UChicagoBSD show that Dachsous and Fat function together to restrict growth by coordinately removing a “core complex” consisting of Dachs, Dlish, and Approximated from the junctional cortex. https://t.co/a88Sbc6pIV
#CellSignaling #Development
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New work by @theajacobs_ @Sfb1348 @uni_muenster shows how actomyosin contractility at #tricellular junctions is modulated to control epithelial permeability in #Drosophila. See our preprint @biorxivpreprint
https://t.co/1OsrTeCpGH
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For my planar polarity follower(s?), we have a new paper out on Fat-Dachsous. Fat-Dachsous are known to interact (signal?) in trans between cells, but we now find a second (more important!) trans-interaction suggesting new models for Fat-Ds clustering https://t.co/yxI9EaUZq4
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Can't argue with first read the Drosophila papers, but read the frog, fish and mouse ones too!
John Wallingford @jbwallingford is next “When in doubt, read drosophila papers” And that is how John arrived to the study of planar cell polarity (PCP) John is sharing his & his team’s most recent work on PCP in Xenopus https://t.co/8xngaMbqJI
https://t.co/vUX0nLnRiC He
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Check out our new preprint on the Activation of Planar Cell Polarity Signaling by Shear Forces to Coordinate Vascular Cell Dynamics done in collaboration with @GalicLab
biorxiv.org
Mechanical stimuli, particularly laminar blood flow, play a crucial role in shaping the vascular system. Changes in the rate of blood flow manifest in altered shear stress, which activates signaling...
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How do butterflies grow intricate nanostructures on their wings? Our work, out today, extends our understanding of the role of actin. By @vickyjlloyd @sheffielduni
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Our latest work on the interplay between microtubule and actin forces during cell shape changes is now out in @NatureComms. Congratulations to @SameedhaThale and @Amrita_Singh_22!!! https://t.co/QAKFyUQ8kF
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Maib (@hannes_maib), @Fran_Bottanelli @petiaadarska @struttlab and colleagues present a toolkit for visualisation of phosphoinositides in fixed cells and tissue, enabling multiplex and super-resolution characterisation of these crucial signalling #lipid. https://t.co/HB6BM5z44o
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We´re hiring! 2-year #postdoc position opening in my lab @uni_muenster to work on membrane trafficking and epithelial tissue dynamics in #Drosophila. For details, see https://t.co/qP5jZiNksB
@the_Node Please RT
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We are hiring a research specialist to help launch our lab at @UChicago. How does biology use physics to sculpt complex visceral organ shapes? We address the dynamic & mechanical interactions between tissue layers that link genes to geometry. https://t.co/ec1G3RqcB1
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📢 We're hiring! 📢 Interested in the mechanisms that control size during development and evolution? We're looking for two postdocs to join our lab @TheCrick. Details below⬇️ Please RT🙏 https://t.co/2cAhRtRFn3
https://t.co/T9vt16j1qa
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Our latest on planar polarity mechanisms: https://t.co/kQYtDBve9Y No long thread (be grateful!) but the highlights are in the graphical abstract. We're excited because after decades of work we think we're moving towards a molecular understanding of what the proteins do.
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!!🚨New pre-print alert🚨!! Super excited to share our first proper foray into developmental biology: https://t.co/9RJ3w30v2u! Below is a little 🧵of how we got here...
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We are super excited to announce the long overdue creation of a UK Wnt signalling research network. Currently comprised of 24 labs across the isles but seeking more - please email WntUK2023@gmail.com to join! Check out our first newsletter below 👇 👇 👇 https://t.co/DtzefqKXlq
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