Sameedha Thale
@SameedhaThale
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Ph.D. student @MatisLab @uni_muenster #microtubules #drosophila | Alma Mater @iiserbhopal 🎓
Münster, Germany
Joined August 2012
Are you interested in microtubules and the regulation of their biophysical properties? We have a PhD position open to students worldwide. Join us! https://t.co/SBu81VKQrI
#PhDposition
jobs-sf.ukmuenster.de
PhD Student (gn*) Developmental and Cell Biology
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This year’s chemistry laureates Demis Hassabis and John Jumper have developed an AI model, AlphaFold2, to solve a 50-year-old problem: predicting proteins’ complex structures. Check out two examples of protein structures determined using AlphaFold2. First up, a bacterial enzyme
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BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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Check out our new preprint on the Activation of Planar Cell Polarity Signaling by Shear Forces to Coordinate Vascular Cell Dynamics done in collaboration with @GalicLab
biorxiv.org
Mechanical stimuli, particularly laminar blood flow, play a crucial role in shaping the vascular system. Changes in the rate of blood flow manifest in altered shear stress, which activates signaling...
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New tool alert! FlyPredictome https://t.co/IXG011rzhc... offers computationally predicted protein-protein interactions through AlphaFold-Multimer. It enriches the analysis of protein complexes by providing measures of interaction strength & contact area, based on the
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Our latest work on the interplay between microtubule and actin forces during cell shape changes is now out in @NatureComms. Congratulations to @SameedhaThale and @Amrita_Singh_22!!! https://t.co/QAKFyUQ8kF
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🦟 By infusing a virtual fruit fly with artificial intelligence, @HHMIJanelia and @GoogleDeepMind scientists have created a computerized insect that can walk and fly just like the real thing. 🤖 🔗 https://t.co/N1IhU4Peo9
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It’s all about last night wonderful dinner at #Oxford #EDBC2023 conference. Very fruitful discussion on cell-cell integrations like on Cytonemes with Prof. Scholpp @scholpp_lab
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TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase
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https://t.co/NYXuRbIiSZ The first research article of TiLab is out.😃 By employing the recombinant tubulin strategy, we reveal the roles of tubulin isotypes in regulating the activities of enzymes for tubulin tyrosination and microtubule stability.
cell.com
Microtubules are non-covalent polymers of α/β-tubulin heterodimers with various isotypes and post-translational modifications. α-tubulin tyrosination/detyrosination is a well-established feature that...
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Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension
molbiolcell.org
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Check out our new paper on the interplay between microtubule protrusive and actomyosin contractile forces during tissue morphogenesis: https://t.co/ONmLdfrSDJ
biorxiv.org
In order to shape a tissue, cell-based mechanical forces have to be integrated into global force patterns. Over the last decades, the importance of actomyosin contractile arrays, which are the key...
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Acute manipulation and real-time visualization of membrane trafficking and exocytosis in #Drosophila. We brought #RUSH, conceived by Franck Perez @Team_FranckP in cultured cells, to the fly, illuminating secretion dynamics in live animals @biorxiv_cellbio
https://t.co/WzUdlduVTs
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Great review on "The wing imaginal disc" by Tripathi & Irvine: "We thank the innumerable researchers who have collectively established the Drosophila wing disc as the most powerful system for experimental biology" https://t.co/eWASYLKKiN
academic.oup.com
Abstract. The Drosophila wing imaginal disc is a tissue of undifferentiated cells that are precursors of the wing and most of the notum of the adult fly. T
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We're hiring! Interested in microtubule cytoskeleton? Fully funded PhD position on an collaborative project on MT mechanics in vitro (& in plant cell) at @Saar_Uni & @RDPlab @ENSdeLyon
#Phdposition #PhD #microtubule #cytoskeleton
https://t.co/0bevCCkjdD
jobrxiv.org
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
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Happy to share the pre-print on the optogenetic #microtubule severing tool (#optokatanin) I've been working on! Fast, reversible and highly localized blue-light-activated MT disassembly.✨ https://t.co/pUvd7tEzhN
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