Sheila Singh Brain Tumour Lab
@sheilasinghlab
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Human Cancer Stem Cell Biology Lab | Dr. Sheila Singh, MD PhD FRCS(C) | Tweets by lab members.
Hamilton, ON
Joined September 2018
Block Biosciences: McMaster startup aims to prevent cancer from spreading to the brain @machealthsci
https://t.co/Jzb54EgEJm
brighterworld.mcmaster.ca
The startup is working on a first-in-class precision medicine that will prevent secondary metastatic brain cancer. It's an innovation that could revolutionize the future of cancer care.
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Glioblastoma, an aggressive brain cancer, depends on the amino acid serine as a fuel source https://t.co/4hz7MuvHAM
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Glioblastoma, an aggressive brain cancer, depends on the amino acid serine as a fuel source https://t.co/Aqqj9i7uaN
nature.com
Nature - Glioblastoma, an aggressive brain cancer, depends on the amino acid serine as a fuel source. A serine-deficient diet has been shown to slow tumour growth in mice.
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Nature News and Views from Daniel Mobilio & Sheila Singh commenting on @DanWahlMD recent Nature paper! https://t.co/bexbJEv28J.
@Nature @NatureNV @CDCR_Mac #GBM
nature.com
Nature - Glioblastoma, an aggressive brain cancer, depends on the amino acid serine as a fuel source. A serine-deficient diet has been shown to slow tumour growth in mice.
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The Singh Lab is excited to announce the release of the 2nd edition of Brain Tumor Stem Cells, in affiliation with the CDCR labs @CDCR_Mac @machealthsci
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A new genome-wide #CRISPR screen identifies BACE1 as a driver of lung cancer #metastasis to the brain, suggesting that BACE1 inhibitors could be repurposed to prevent brain metastasis in #NSCLC. @sheilasinghlab @McMasterSurgery
https://t.co/EDcBJE0IW2
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Alzheimer’s protein found to drive #lungcancer brain metastases. Blocking it with a drug originally made for Alzheimer’s stopped tumour growth. Huge potential for repurposing treatments & a standout example of smart, cross-disciplinary science, led by @sheilasinghlab & team. 📄
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.@sheilasinghlab was instrumental in making a discovery that could provide hope for lung cancer patients. The @ClevelandClinic and @caseccc also contributed. #LungCancer #Alzheimers #CancerResearch
https://t.co/CkXLEpVDHC
mugglehead.com
They found that a protein associated with the neurodegenerative disease helps lung cancer move to the brain
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Today marks the 5-year anniversary of Dr. Todd Mainprize’s passing. Dr. Mainprize served as the Division Head of Neurosurgery at Sunnybrook Health Sciences Centre. Forever remembered as THE FIRST DOCTOR IN THE WORLD TO BREAK THE BLOOD-BRAIN BARRIER USING FOCUSED ULTRASOUND,
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The Singh Lab, in collab with the Cleveland Clinic & Case CCC, have discovered how a protein linked to Alzheimer’s disease aids lung cancer's spread to the brain. Raising hope that existing Alzheimer’s drugs could help prevent mets. https://t.co/tikMUNgd40
@caseccc @CDCR_Mac
healthsci.mcmaster.ca
Researchers at McMaster University, Cleveland Clinic and Case Comprehensive Cancer Center have uncovered how a protein long associated with Alzheimer’s disease helps lung cancer spread to the brain –...
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New publication! A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis | Science Translational Medicine https://t.co/Rn3WXAVG3X
@ScienceTM
science.org
Beta-secretase 1 promotes the spread of lung cancers to the brain through epidermal growth factor receptor signaling.
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Dr Singh presenting at the International Conference on Brain Tumor Research and Therapy in Hokkaido, Japan. #ICBTRT
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Excited to share that Dr Singh will be speaking at the upcoming Cell Symposia: Gene and Cell-Based Therapies – Progress in Clinical Translation taking place November 2–4, 2025 in Los Angeles, CA #CSStemCells2025 @CellStemCell @CellSymposia
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During a recent visit to St. Jude, Dr Sheila Singh had the pleasure of meeting Dr Martine Roussel, a luminary in medulloblastoma research. On her way out, she appreciated Dr Roussel’s plaque commemorating her induction into the NAS. @StJudeResearch #Medulloblastoma
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🔬🧠Brain Cancer Canada is proud to award $85,000 to @sheilasinghlab and her team at @McMasterU on IMMUNOTHERAPEUTIC TARGETS FOR RECURRENT MEDULLOBLASTOMA. Click the link to read more about this research grant: https://t.co/EPI2eqhmj4 This announcement marks the final in a
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While at the University of Manitoba to deliver the Arnold Greenberg Keynote Lecture, Dr Singh caught up with Dr Katyal and had some great discussions with his fantastic lab team. @CCMB_Research @1sachinkatyal
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Dr Singh had the incredible honor to deliver the Dr Antoine Hakim keynote lecture at the Ottawa Brain Health Research Institute on May 16. Invited by the wonderful Dr Jahani-Asl. @arezujahanilab @uOttawa
#BHRD2025
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We were honoured to host Dr. Sheila Singh, Surgeon-Scientist from @McMasterU, as a keynote speaker at #BHRD2025 at @OttawaCmm. She delivered an incredible talk on ‘Targeting Clonal Heterogeneity in Treatment-Refractory Glioblastoma with Novel and Empiric Immunotherapies.’
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Job Opportunity at Singh Lab - Research Lab Technician https://t.co/ekIV0JLaBJ
cdcr.mcmaster.ca
Join a team at the forefront of brain tumor research and make a direct impact on advancing life-saving science. Sheila Singh’s lab is looking for a Research Lab Technician (III) who will provide...
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We were honoured to host Dr. Sheila Singh, Surgeon-Scientist from @McMasterU, a trailblazer in pediatric brain cancer research & a champion of mentorship in academic medicine. 👏 #MentorshipMatters #ResearchDay2025 #CancerResearch
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