Rob Hynds
@robhynds
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Scientist studying epithelial biology, stem cells and cancer @EpiCENTR_ICH. ⚽️ @BCFC 🏃🏻♂️ @LondonHeathside
London, UK
Joined February 2009
Lizzie Maughan @UCLchildhealth led this collaboration with Wenhui Song’s lab @UCLDivofSurgery to develop a bespoke airway stent for a 5-month-old with near complete laryngeal stenosis. The novel 3D printed stent enabled safe airway reconstruction. 📄
advanced.onlinelibrary.wiley.com
A programmable interpenetrating double-network architecture, created via 3D-TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structur...
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New preprint! We know cancer cells with somatic mutations are selected to evade the immune system. With @imartincorena Peter Campbell @ZJL1435957 @QuotientTx, we asked if immune cells with somatic mutations are also selected to fight cancer. https://t.co/2CWjTgZ3nY 1/5
biorxiv.org
Cancer cells evolve to increase fitness and evade the immune system, but it is not clear if tumor infiltrating lymphocytes (TILs) undergo selection for somatic mutations that augment anti-cancer...
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Early Career Opportunity, CDB, UCL Mentorship, world-class facilities, and a supportive environment. We are particularly interested in researchers in Synthetic Dev. Biol. Mechanobiology and AI approaches. #AcademicJobs #EarlyCareerResearcher #UCL #DevelopmentalBiology
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An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | #helpisonthe way!
nejm.org
Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...
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Great opportunity in a great team!
🚨 PhD available in our lab 🚨 exploring blood immune multi-omics to detect lung cancer years before clinical diagnosis in a unique cohort of >10k CT screened individuals. ✅ Wet & dry lab ✅ September 2025 enrolment ✅ UK tuition fees only https://t.co/uWBDZAIGHO
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Want to get 31% "younger" biologically? Play 90 mins of Bundesliga soccer. The catch? You're back to baseline within 24 hours. 🤣This isn't hype, it's a wild finding! A new study reveals GrimAge (the most robust epigenetic clock for mortality risk) shows a significant dip after a
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🤯 🦠 🫁 ♋️ (@Nature) Respiratory viral infections awaken metastatic breast cancer cells in lungs https://t.co/R8Vo63ZdNG
nature.com
Nature - Mouse models show that respiratory infections from viruses such as influenza and SARS-CoV-2 can trigger metastasis of dormant breast cancer cells in the lungs, a finding supported by...
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The AJRCMB Call for Papers on Lung Repair Models and Mechanisms - launched at the Vermont Stem Cell Conference earlier this month - is now open! Please consider submitting your next paper here. Thanks to @JanetteKBurgess and Andrew Halayko for making this happen 🙌
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⏱️Only 3 weeks left to submit your abstract to #BALR2025, "New Horizons in Respiratory Research" Cardiff, 8-10 September 2025. ✔️ Expert panel discussion on research priorities ✔️ ECR awards ✔️ Conference dinner in stunning location on Cardiff Bay. Submit:
balr.co.uk
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Great to see @krijndijkstra's work from @TheCrick published! He developed clonal organoid lines from NSCLC tumours and PDX models. Immune evasion varied between clones from the same tumour, highlighting intratumour heterogeneity and providing a model to study it.
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Excited to share our new paper with Sheila's lab: we performed an in vivo genome-wide CRISPRa screen using a lung TRACERx PDX model to uncover drivers of brain metastasis. BACE1 emerged as a key hit - especially interesting given ongoing therapeutic efforts in Alzheimer’s.
New publication! A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis | Science Translational Medicine https://t.co/Rn3WXAVG3X
@ScienceTM
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Great to see so many familiar faces registered for the 20th Anniversary Stem Cells, Cell Therapies & Bioengineering Conference in Burlington in July. There’s still time to register and for trainees to book a spot on the unique pre-conference workshops. https://t.co/vbsFFhaeAZ
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Got a radical idea that doesn’t fit the mold? #HFSP supports bold, high-risk postdoctoral research in #LifeSciences 🧪 Challenge the norm. Go international. Think beyond disciplines 💪 Apply now! 💥 Deadline May 15 | Initiate LOI by May 7 🔗 https://t.co/T99VInDhhj
#sts
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@lungsforliving @robhynds @EpiCENTR_ICH Read more about this research in our ‘First person’ interview with Yuki Ishii and Jessica Orr: https://t.co/yQ4geOH2V4
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🚨Today our airway basal cell proliferation screening work is published @J_Cell_Sci! We found that multiple Wnt activating compounds promote basal cell proliferation and validated 1-azakenpaullone in vivo. https://t.co/pj6iiM7Ja2
journals.biologists.com
Highlighted Article: A high-throughput screen of 1429 compounds in primary human airway epithelial cells was used to identify that Wnt pathway-activating compounds increase cell proliferation.
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🚨Announcement! We extended the abstract submission deadline to Monday 7th of April! Don't miss this chance to present your work and win one of our prizes 🏆 @TheCrick @the_Node @YEN_community @InesSequeira7 @robhynds @STEMCELLTech @STEMCELLTech @Crick_SCF @GOS_ICH_SCI
🚨 Less than 2 weeks to our abstract submission deadline! 🚨 Don't miss the chance to present your work to the UK #stemcell community and win one of our prizes 🏆! Submit here by the 4th of April:
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Applications are now open for the Summer studentships 2025, in collaboration with @ActionPFcharity, @PFNI_NIRELAND and @Breathingmatter. They cover stipend and consumables for up to 8 weeks over the summer period. For more info and to apply https://t.co/PoSZjGB0Mo deadline 10/05
balr.co.uk
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🚨 Less than 2 weeks to our abstract submission deadline! 🚨 Don't miss the chance to present your work to the UK #stemcell community and win one of our prizes 🏆! Submit here by the 4th of April:
docs.google.com
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