Rikeish R. Muralitharan MD, PhD
@rikeishm
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MD. PhD. Research Fellow @FZMarques lab, @monashVHI Gut microbiome. SCFAs. Hypertension. Immune system. 🏳️🌈
Melbourne, Victoria
Joined March 2011
1/10 My baby is finally out in @CircRes ! I am super proud and excited to share this work. https://t.co/zE0Qhmlf80
ahajournals.org
BACKGROUND: Fermentation of dietary fiber by the gut microbiota leads to the production of metabolites called short-chain fatty acids, which lower blood pressure and exert cardioprotective effects....
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🎉 ECI Excellence 2025 nominations open 🎉 We are calling for nominations of ECIs (students → 8 yrs post-PhD) who achieved something excellent in 2025! ✅ Any achievement counts ✅ Self-nominations welcome ✅ Australasian only 📅 Deadline: 24 Nov 👉 https://t.co/hQ55DCUy87
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Our new @NatRevGastroHep review is now online "Parental diet and offspring health: a role for the gut microbiome via epigenetics" Co-authors Chaoran Yang, @Matt_Snelson & @SamElOsta1 A very exciting area of research with lots of potential https://t.co/RLdSwOUU6E
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Early vascular aging (EVA) is not only a concept that applies to adults. This is an expert consensus on the definition of EVA in youth: https://t.co/OT3XcXdSf2 "EVA in youth characterizes the precursor alterations of small- and large arterial structure and function due to risk
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Very honoured and grateful for the award @ISHR_AUS. Thank you to all co-authors who helped get it across the finishing line
Congratulations to @rikeishm for winning the @ISHR_AUS Postdoctoral publication prize for his paper “Gut Microbiota Metabolites Sensed by Host GPR41/43 Protect Against Hypertension” published in @CircRes
https://t.co/t4VDpgCvoU
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For more info and recruitment, please check out
marqueslab.com
Are you fascinated by gut microbes? Do you want to volunteer in research to lower blood pressure? Then click to join us in an exciting journey
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Big milestone achieved! GRAINS-BP is officially underway as we’ve randomised our first participant. This is a major step towards generating evidence that could change how we treat hypertension. Huge thanks to @FZMarques , our collaborators, funders, and PhD student Malindi!
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Engineering the gut microbiome in people with hyperoxaluria to avoid kidney stones https://t.co/OK3aaUoBpP
@ScienceMagazine
science.org
Precision microbiome programming for therapeutic applications is limited by challenges in achieving reproducible colonic colonization. Previously, we created an exclusive niche that we used to...
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Heading to CSANZ/ISHR2025 in Brisbane next month? There are ECI travel awards available for students and ECIs (<8 years post PhD). Members check your📧for details on how to apply.
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A great session! Congratulations to all speakers including our PhD student Chaoran Yang His paper 👇 https://t.co/ztdNy6XPSy
@MonashVHI @MonashBDI
https://t.co/fbMzwQmv6M
tandfonline.com
The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined ...
That's a wrap for #MVIF 40 in Pacific zone THANK YOU to #microbiome people who tuned in & all the amazing speakers! 📢 you can submit your work for October and November https://t.co/i6eJcbnJiM
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How can a high-fibre shake protect your heart? ♥️ New @MonashUni research from @FZMarques lab shows SCFAs - produced when gut bugs digest fibre - activate receptors that cut cardiovascular risk by 20%. Read:
monash.edu
Melbourne researchers have uncovered a way to help people lower their risk of cardiovascular disease - simply by drinking a shake. @LanaMurphy #9News
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@CircRes Interorgan Crosstalk in #HF & #Cardiometabolic Diseases Compendium #Gut-Heart Axis: The Role of Gut #Microbiota & #Metabolites in Heart Failure https://t.co/q6aaLxzSfw Authored by @matt_snelson & colleagues. @WilsonTangMD @FZMarques @inanna_nalytica @rikeishm
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Registration is open and free to attend
🗣️Speakers announced: EMCRs do not miss out on this all-star line up Learn tips to support your NHMRC Investigator Grant Application Proudly brought to you by: @VicCVRN @SACVRN @heartfoundation
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🗣️Speakers announced: EMCRs do not miss out on this all-star line up Learn tips to support your NHMRC Investigator Grant Application Proudly brought to you by: @VicCVRN @SACVRN @heartfoundation
🚨 EMCRs in cardiovascular research! Join our free webinar on the NHMRC Investigator Grant Scheme 🧠 📅 June 3 | 🕥 10:30am–12:00pm ACST 💡 Hear from successful applicants & peer reviewers 🔗 Register now: https://t.co/9tXDNFIcC0
#NHMRC #CardioResearch #EMCR #SACVRN #VicCVRN
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It was graduation day today 🤩 Congratulations to Dr @ChudanXu & 2 of honours students who graduated today 🤩 and a big thanks to our amazing team for helping to celebrate it (wait until she sees her desk tomorrow 🥹) @MonashUni @MonashVHI
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Big thanks to editors @gabrieleschiat1 & @mkontari and @CircRes for the opportunity to write one of the interorgan crosstalk reviews in #heartfailure If you want to learn more about the gut-heart axis, check out https://t.co/TXVEzg6U0J Authors include @Matt_Snelson @rikeishm ++
ahajournals.org
Heart failure is a global health issue with significant mortality and morbidity. There is increasing evidence that alterations in the gastrointestinal microbiome, gut epithelial permeability, and...
@CircRes May 23rd Issue is Out! Compendium on Interorgan Crosstalk in Heart Failure and Cardiometabolic Diseases In this issue read 14 reviews & 5 Research Letters: https://t.co/STHYRFUtry
@gabrieleschiat1 @mkontari
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Our review on the gut-heart axis published in @CircRes is now out https://t.co/TXVEzg6U0J We cover gut #microbiome, 'leaky gut', foods & metabolites, +++ Congratulations @Matt_Snelson @rikeishm and our co-authors 👏 @MonashVHI @MonashBDI @Monash_FMNHS
ahajournals.org
Heart failure is a global health issue with significant mortality and morbidity. There is increasing evidence that alterations in the gastrointestinal microbiome, gut epithelial permeability, and...
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Work performed at @MonashVHI @MonashBDI @Monash_FMNHS @MonashUni with support from @nhmrc, @heartfoundation & Sylvia and Charles Viertel Foundation 🙏
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This is important because it translates findings in animals and demonstrates that these receptors that allow our gut microbes to communicate with our body and regulate physiological responses such as blood pressure may be a new target for therapy
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This is important as: i) We still don't understand most gene-by-environment interactions that regulate blood pressure ii) Most evidence of these mechanisms is in mice - for example our paper in @CircRes
https://t.co/Jj53MWG6hs or @circulation
ahajournals.org
Background: High blood pressure (BP) continues to be a major, poorly controlled but modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet poor in fiber is...
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Our latest paper is out in Cardiovascular Research @CVR_TomaszGuzik @ESC_Journals We used a genetics approach to provide human evidence of gut-to-host crosstalk in how blood pressure is regulated @ctavaresleticia @Matt_Snelson @rikeishm
https://t.co/L0QfFUIuC0
academic.oup.com
Gut microbial metabolites called short-chain fatty acids (SCFAs) confer protection against cardiovascular disease (CVD) and its primary risk factor, hypert
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