Ralser Lab
@RalserLab
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Joined August 2013
Registration is open for our St Nicholaus Symposium, a meanwhile traditional event to get our Berlin Mass Spectrometry community together @ChariteBerlin @MDC_Berlin , and @BerlinUAlliance
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Obituary: John Gurdon (1933-2025) Biologist who made cloning possible https://t.co/rK5urZzl7S
nature.com
Nature - He showed that specialized cells retain the genes to form an organism.
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We don't know the (phenotypic) consequences of most mutations. Good news, the proteome can help! And it predicts phenotypes in new environments.
science.org
Understanding how genetic variation translates into complex phenotypes remains a fundamental challenge. In this work, we address this by mapping genome-to-proteome relationships in 800 progeny of a...
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Difficult to predict Nobel Prizes... but if you would ask me for a gut feeling, I would look closely at Metabolism this year.
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the sign is still there, but the the once proud, highest tree of Berlin is gone. Lost in the storm. #monuments of climate change.
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Are you a theoretical biologist intererested in the ecology and evolution of metabolic interactions among microorganisms? Do you like to work with experimentalists? Do you have a PhD and experience in modelling + statistics? Then this might be for you: https://t.co/eABgl919XO
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Registration is now open for early-career researchers to apply for a funded place at our Workshop on Revisiting Metabolic Fundamentals, organised by @lydfinley& @WilhelmPalm. Find out more and apply at https://t.co/oBmoEsHATn
#BiologistsWorkshops
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Vividly remember the journal club when we discussed this manuscript- 15 years ago- now retracted, 15 years later. Take home message: if you make big claims, try to have direct evidence - in this case AS analytics, which would have been availbe at the time
nature.com
Nature - The journal Science retracts a headline-grabbing study, but the authors vigorously defend their data and say the retraction is unwarranted.
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Why are antiungals often ineffective? We mined current clinical guidelines, and found that many drugs that are administered to patients with high risk of fungal infections, interfere with antifungals.
microbiologyresearch.org
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The Yeast2025 meeting in Paris is over, and was so much fun. It was exciting to see a room full of yeast biologists, with more than 500 people. It was also great to be part of the dream team of organizers, led by Gilles Fischer!
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Registration is open (and free) for this year's Midwest Metabolism/Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) Annual Conference at the University of Michigan November 10–11, 2025. Hope to see you there! https://t.co/78aHpvoTkN
vai.org
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
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Loa Loa, an eye worm infection, is a neglected tropical disease. Diagnostics is only self-reporting, i.e. if some sees a worm in your eye. Proteomics can now help to indify biomarkers and to develop diagnostics
academic.oup.com
Loa loa infection significantly alters the human host plasma proteome. Differentially abundant proteins provide insights into the pathophysiology and allow
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Proteome-driven regulation of fatty acid biosynthesis seems important for glucose-stimulated insulin secretion.
analyticalsciencejournals.onlinelibrary.wiley.com
Pancreatic beta cells secrete insulin in response to rising glucose levels, a process known as glucose-stimulated insulin secretion (GSIS). Here, we acquire proteomes of rat pancreatic INS-1 832/13...
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Plasma Proteomics Reveal Distinct Signatures in Occult and Microfilaraemic Loa loa Infections ✅ Just Accepted ✍️ @kurthgroup @ralserlab @BNITM_de 🔗 https://t.co/CiCssuBq8q
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https://t.co/ki7JQP0Kku Simran's metal ion manuscript made i to the cover of @CellSystemsCP . Always told everyone that metal ions rock :-)
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Just under a week left to get applications in for these positions. ⏰
We're hiring for 2 postdocs to work in our lab in London on the newly announced Wellcome Trust SynHG project. If you know people looking to work on big-scale ambitious science like this, please RT and share this with them. Apply by 7/20, interviews in Aug. https://t.co/TOVjZ3osO5
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My 9-nine year old found a Galley Proof on my desk. This is what she gave me back :-)
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When #AlphaFold2 came out, we wondered: Could it help us understand how enzymes evolve? So we tried it—and it worked!
nature.com
Nature - By combining structural biology and evolutionary genomics analyses, the evolution of enzymes over 400 million years is shown to be governed by catalytic function, metabolic network...
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