Taka Nojima
@pol2rna
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Now PI in Japan, Was SRF in the UK @UniofOxford. Love nascent transcript and RNA processing. Views my own.
Japan
Joined May 2015
A mechanism of synergistic Mediator recruitment in RNA polymerase II transcription activation revealed by single-molecule fluorescence https://t.co/QPKjhn92si
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今年の生化学会の任務終了。名古屋大 鈴木洋先生と最終日に担当した、シンポジウム 遺伝子x 相分離は、スピーカーの先生方とフロアの皆様のおかげで大盛況でした。ありがとうございました😊
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📢新刊・本日発行 実験医学増刊号『徹底解剖 タンパク質発現異常 疾患の原因が見えてくる！新機構27選』 転写バースト，G4構造，有害エクソン，非典型翻訳，リボソーム不均一性，共翻訳フォールディング，凝集体形成，アミロイド，などなど
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『タンパク質発現異常 ― 疾患の原因が見えてくる！新機構27選』（実験医学増刊号）が発売になりました！ 田口英樹先生とともに編集を担当しました。転写・RNA・翻訳・プロテオスタシスまでを幅広く俯瞰しながら、分子レベルで疾患を読み解く一冊です。
＼新刊発行のご案内④／ 本日『実験医学増刊 徹底解剖 タンパク質発現異常 疾患の原因が見えてくる！新機構27選』が取次様搬入です。 異常タンパク質発生のメカニズムを、転写・RNA・翻訳・タンパク質の4カテゴリで総覧できる！ 雑誌棚、基礎医学棚で展開をお願いします！ https://t.co/bKuwpYhp5Z
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BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has
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From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes https://t.co/HM6S9DQQpt 🧬🖥️🧪 https://t.co/Yw1nbqEfLd
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Nascent CUT&Tag captures transcription factor binding after chromatin duplication https://t.co/o3ZNrO8qPo
#biorxiv_genomic
biorxiv.org
DNA replication strips off all chromatin proteins, which must be reassembled behind the replication fork. To track chromatin reassembly on newly synthesized DNA, we developed Nascent CUT&Tag, a...
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Virus driven Disruption of Transcription Termination (DoTT) generated cellular Z-RNAs are bona fide ZBP1 ligands driving cell death as a host response to counter viral disruption of the cellular transcriptional machinery @Nature 🇺🇸🇩🇪 @FoxChaseCancer
https://t.co/w6OvJixT7C
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New Online! The new era of single-molecule RNA modification detection through nanopore base-calling models https://t.co/4QzxowoU6b
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Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science!
science.org
Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage...
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Excited and grateful to share our paper describing how KCTD10 detects collisions between replication and transcription. Huge thanks to my mentors, collaborators, and reviewers who made this possible! @Nature @MayoClinic
https://t.co/fN3VVdnDha
nature.com
Nature - KCTD10 interacts with the DNA replication machinery and the RNA polymerase complex, inducing ubiquitination and removal of the transcription machinery in the event of co-directional...
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Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
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New Online! Elucidating the coordination of RNA processing using short-read and long-read RNA-sequencing methods https://t.co/Zc7HRNOQ2m
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当研究室のユエくんが学振DC2に採用されました🎉めでたい🎉昨年の中山さんに引き続き、頼もしい学生さんと研究できて嬉しい限りです😃ユエくんは、AIで転写ルールを明らかにします！
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論文査読者がひどいというのはありがちだが、度を越した例があるという記事。記事中に人格を否定するようなひどい査読コメントの実例集がある。具体的な対策も載っていて、雑誌を選ぶとかもあるが、editorに対して連絡するというのは実際的な気がする。Nature。 https://t.co/ULBwbN3f7X
nature.com
Nature - Scientific societies, journals, editors and researchers are pushing back against mean-spirited peer reviews.
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🚨New preprint from our labs (STOP lab & Nojima lab @pol2rna)! @kopczynska_m and Chihiro Nakayama have been digging into how chromatin remodeller SETD2 controls the start and end of transcription 👇 (1/5) https://t.co/8VQKNov5dR
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