Bjoern Papke
@papkephd
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RASologist interested in #cancer and systems biology. Trained @mpimoph, @DerLabUNC and @ChariteBerlin. #RAS #KRAS #HRAS #NRAS #PancreaticCancer #organoids
Berlin, Germany
Joined October 2016
(1/4) 🚀 We are thrilled to announce the 2nd Targeting RAS Symposium! 🎯 Join us Oct 8-10, 2025, at Palacio de Congresos, Salamanca, Spain. @AmbrogioLab @EstherCastel @DrostenMatthias @lab_santamaria @molina_arcas
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Top 4 things to know about doing science: 1. You need to have someone you can talk to 2. One-on-one discussions are the best 3. Think about discussions as improvisations and use the ‘yes, and’ rule 4. Create a safe space so both of you feel open to saying seemingly silly things
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We’re thrilled to announce the launch of Center for RAS Therapeutics to target the RAS oncogene in cancer. The first of its kind Center aims to advance new treatment approaches for patients with RAS mutant cancers. Learn more: https://t.co/gamUtXX9kO
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Excited to share our latest in @NatureMedicine✨ We present a detailed clinico-genomic landscape of pancreatic adenocarcinomas With important implications for RAS 🎯 therapies Expertly co-led by @AnnaVarghese4 and @MariaAPerry. w/@EileenMOReilly & colleagues @MSKCancerCenter
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KRAS inhibitors: resistance drivers and combinatorial strategies: Trends in Cancer https://t.co/G3awCHgAum
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KRAS inhibitors: resistance drivers and combinatorial strategies: Trends in Cancer
cell.com
In 1982, the RAS genes HRAS and KRAS were discovered as the first human cancer genes, with KRAS later identified as one of the most frequently mutated oncogenes. Yet, it took nearly 40 years to...
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🚨 Thrilled to share our latest featured review with @tamaraisermann, @cjder23, and C. Sers: "KRAS Inhibitors: Resistance Drivers and Combinatorial Strategies" now #OpenAccess in @TrendsCancer! 🔬 https://t.co/xEKTffVzOK Please read it and don’t forget to cite, cite, cite! 😉
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An #OpenAccess review on current status of KRAS inhibitors, resistance drivers & potential combinations from @derlabunc @cjder23 @papkephd & colleagues @DKFZ @ChariteBerlin in @trendscancer As always very informative illustrations: A: Frequency of KRAS Allelic alterations across
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👇🏻👇🏻👇🏻not to be missed!
🗓️📢🫵The Symposium “Targeting #RAS: new avenues and challenges” is coming up! ▶️ September 1️⃣3️⃣-1️⃣5️⃣ at the @CICancer_com #Salamanca (Spain) with great spearkers and program to catalyze discussions on RAS-driven #Cancers & new therapies. @SmallGTPases 📍Registration open‼️👇
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Glad that this @NorthWestCancer funded work by @fiona_hood, Yasmina and Roz is finally out in @oncogenejournal. Ras abundance in ~90 cell lines and tissues. Challenges ideas explaining KRAS mutation frequency in cancer. @LivUniISMIB
Ras protein abundance correlates with Ras isoform mutation patterns in cancer. Comprehensive atlas of Ras isoform protein abundance in tissues and commonly used cell lines. #kras #hras #nras
https://t.co/kwsiWsBzGt
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Come see Wayne present at 1pm this afternoon at #CellBio2022 in the "Beyond Pretty Pictures: Quantitative Methods for Learning Cell Biology from Microscopy Datasets" subgroup!
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We are raising awareness for #pancreaticcancer @ChariteBerlin. Thanks for participating @ChristineSers and @derlabunc Berlin. Waiting to see awareness pictures from @derlabunc @bryant_kl @ UNC_Lineberger @AndrewMWaters @KRASkickers. #pancreaticcancerday #pancreaticcancermonth
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How it started vs. how it's going... From the @cjder23 #postdoc room @UNC_Lineberger to our own #cancerresearch careers. @bryant_kl @papkephd
#killkras @KRASKickers #RASSymposium22
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Excited to share our @derlabunc #CancerResearch identifying BCAR1/p130Cas and TUBB3/betaIII-tubulin as #KRAS-mutant #PancreaticCancer therapeutic vulnerabilities and #MYC regulators. Thank you @AmericanCancer @ACS_Research for support! #KillKRAS
https://t.co/GwXRJFtl76
cell.com
Using integrated analysis of genome-scale screens, Waters et al. identify BCAR1 and TUBB3, encoding p130Cas and βIII-tubulin, as two pancreatic cancer vulnerabilities that, when inhibited, sensitize...
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Very excited that our 5-year work is out today! Real-time drug response measurements in #organoids with single-cell resolution. https://t.co/PaMlyRxpjU Fantastic work by Bas Ponsioen and thanks to our great collaborators. #KRAS #SingleCell #colorectal #cancer
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Nach der #AstraZeneca-Freigabe und einer #maiLab-Nachtschicht hier alles, was man jetzt wissen muss:
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Finally secured the first NIH/NCI R01 @HwangLab , with a bonus, R37 conversion. Feels grateful for all the support from my department and colleagues @ucdavisbiology @UCD_Cancer. Now hiring a postdoc!
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Great summary of “The epic battle with cancer's 'Death Star'” by the Guardian featuring @cjder23 @derlabunc @kevansf and many more. #killRAS #cancerbiology #KRAS
theguardian.com
Forty years after the mutant genes that cause the deadliest cancers were discovered, drugs that target them could be approved
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Trying to find a #biosensor for your studies, or recently publish a biosensor and want to share? Check out our biosensor database, where you can search for biosensors and submit newly published biosensors! https://t.co/sXo2yeXiwf
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