Oncogene Journal
@oncogenejournal
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Oncogene aims to make substantial advances in our knowledge of processes that contribute to cancer by publishing outstanding research.
London
Joined July 2018
Study revealing a novel regulatory mechanism of ER-membrane protein complex in #HepatocellularCarcinoma progression through lipid metabolism 👉 https://t.co/mtRcTf16eY
nature.com
Oncogene - Unveiling EMC6 as a novel pathogenic determinant in hepatocellular carcinoma: orchestration of lipid metabolism through regulation of lipid droplet-associated enzyme HSD17B13
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Did you know that HOMER3 plays a key role in oral squamous cell carcinoma progression and drives chemoresistance? https://t.co/ckeA3vIk1V
#OSCC
nature.com
Oncogene - HOMER3 drives oral squamous cell carcinoma progression through TRPV6 calcium influx and TUBB3 microtubule stabilization
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Read about the crucial role of XLH-36, a micropeptide, in Triple-negative #BreastCancer metastasis here: https://t.co/enGz50Ecea
nature.com
Oncogene - The novel endogenous micropeptide XLH-36 binds Gemin4 to promote triple-negative breast cancer metastasis
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New research uncovers FRA1 as a key driver of melanoma metastasis—revealing actionable targets like AXL, CDK6, and FSCN1 that could pave the way for new cancer therapies. https://t.co/CEKo15NMS0
nature.com
Oncogene - FRA1 drives melanoma metastasis through an actionable transcriptional network
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Latest study reveals that a novel SN38-PROTAC targeting RPL15 boosts anti-PD-1 immunotherapy by activating cGAS-STING signaling and enhancing tumor immunity with minimal toxicity. Read more about this new research >>
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Online now: New research reveals how the enzyme SQLE fuels #bladder cancer by rewiring mitochondrial metabolism—and shows that an existing FDA-approved drug could help stop it. #CancerResearch #BladderCancer
https://t.co/NX0DfOuoDl
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New study reveals that circCLASP1 drives #breast cancer progression and immune evasion by stabilizing GLI1, highlighting its promise as a novel biomarker and therapeutic target. Available to read >>> https://t.co/XgkDvKDc1h
nature.com
Oncogene - Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer
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New research uncovers how the HBx-KLF16-C12orf49-PD-L1 axis drives growth and immune evasion in HBV-related liver cancer—revealing a potential new target to enhance anti-PD-L1 therapy in HCC. #LiverCancerResearch #Immunotherapy
https://t.co/Qwvayr625k
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New study reveals that chaperone-mediated autophagy fuels breast #cancer progression by enhancing the cross talk between tumor and endothelial cells. #CancerResearch #Autophagy #Angiogenesis
https://t.co/MG7vGzOtYH
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Latest study reveals that the PML-mTOR-RONIN complex regulates ribosomal protein genes to control senescence in triple-negative breast cancer, offering fresh insights into senescence-targeted therapies. #CancerResearch #TNBC
https://t.co/GCDc7mCTPg
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New research shows that blocking key survival pathways may finally open the door to effective treatments for NF2-related schwannomatosis—a rare genetic condition long without drug options. Read more 📖 now >>> https://t.co/SDFBDvOe8q
nature.com
Oncogene - BET proteins mediate survival mechanisms in human schwannoma model cells challenged with trametinib but not brigatinib
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Whole-genome sequencing transforms metastatic colorectal cancer care. Latest study shows WGS identifies new biomarkers, doubling access to personalized, biomarker-based treatments. Discover how genomics and organoid testing redefine precision oncology. https://t.co/dYzvlU2Ms9
nature.com
Oncogene - Clinical implications of whole genome sequencing in metastatic colorectal cancer
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WBP11-driven suppression of NONO UFMylation unveils a previously unrecognized regulatory axis that fuels #hepatocellular carcinoma progression, offering new therapeutic avenues in targeting posttranslational modification dynamics! Read now 🧬🧫🔬 https://t.co/KPSgIJC4Ix
nature.com
Oncogene - WBP11 inhibits UFL1-mediated UFMylation of NONO to drive hepatocellular carcinoma progression
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Could histamine H1 receptor, HRH1, be the new target for treating #glioblastoma? https://t.co/0KwYW1e6gV
#GBM
nature.com
Oncogene - HRH1-targeting mAb: a precision therapeutic strategy for Glioblastoma
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A novel, non-genetic mechanism to inhibit #apoptosis Read here 👉 https://t.co/s9H9QpUu9Q
#OpenAccess #CancerResearch
nature.com
Oncogene - Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution
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New study identifies Meflin as a promising target in refractory 🦴#osteosarcoma and presents a novel antibody-drug conjugate therapy showing high efficacy in preclinical models. https://t.co/cGs3Gh6iAC
@esaki_nobutoshi
nature.com
Oncogene - Meflin is a druggable target using antibody-drug conjugates in progressive osteosarcoma
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hnRNPM supresses proliferation of colorectal carcinoma through regulation of #splicing
https://t.co/HglmA3iyGE
nature.com
Oncogene - Emerging roles of RNA-binding protein hnRNPM in alternative splicing regulation and UTMD mediated sh-hnRNPM/CMBs suppress the proliferation of colorectal cancer
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Delving into the role of the ATM-ZDHHC20-KAP1 axis in 🧬DNA damage repair https://t.co/qiTVj6EebJ
#DDR #CancerResearch
nature.com
Oncogene - ZDHHC20-mediated S-palmitoylation of KAP1/TRIM28 promotes DNA damage repair
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Hot off the press from @itsTaps & co-workers 👉Circadian disruption alters mammary gland morphology https://t.co/UpQ6V7ng69
#BreastCancer #OpenAccess
nature.com
Oncogene - LILRB4 regulates circadian disruption-induced mammary tumorigenesis via non-canonical WNT signaling pathway
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Could targeting BRD4 be a viable strategy to augment the efficacy of #radiotherapy forđź§ #glioblastoma treatment? https://t.co/efn5x88yBe
nature.com
Oncogene - BRD4 inhibition sensitizes glioblastoma to radiotherapy by suppressing super-enhancer-driven COL1A1
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