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OsmanLab

@osman_lab

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Studying the mysteries that surround the genome of the cell's powerhouse

Munich
Joined November 2019
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@osman_lab
OsmanLab
2 years
Thrilled to announce that our latest paper on the novel mitochondrial HMG-box protein, Cim1, just got published in @NAR_Open. Surprisingly, Cim1 antagonizes the TFAM homolog Abf2 in #mtDNA copy number regulation. Congrats, Simon!! #lmu #mitochondria 🔬.
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@osman_lab
OsmanLab
5 months
🚀 Excited to share our latest work on Mrx6 and mtDNA copy number regulation, now available on @biorxivpreprint ! We uncover how Mrx6 and Mam33 interact with the Lon protease Pim1 to control substrate degradation. 🔬 Check it out here: #mitochondria #mtDNA.
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@osman_lab
OsmanLab
5 months
RT @biorxiv_cellbio: Mrx6 binds the Lon protease Pim1 N-terminal domain to confer selective substrate specificity and regulate mtDNA copy n….
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@osman_lab
OsmanLab
7 months
RT @frank_pado: 🚨 New segmentation model alert! 🚨🥳 . You can finally use InstanSeg in our #BioImageAnalysis software #CellACDC! . InstanSeg….
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@osman_lab
OsmanLab
10 months
RT @SchmollerLab: It is not trivial to make the right amount of histones in different nutrients, when #cellsize, growth rate, and S-phase d….
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@osman_lab
OsmanLab
10 months
Huge thanks to @anjbadri and @nitish_dua3 for spotlighting our work in @embojournal ! 🙏🧬 Check out the full article here 🚀🔬 #mtDNA #mitochondria
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@osman_lab
OsmanLab
10 months
RT @embojournal: Disordered regions in the IRE1α ER lumenal domain form condensates in vitro and mediate its stress-induced clustering and….
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@osman_lab
OsmanLab
11 months
RT @Dpla_: Glad to share this little piece referring to last paper published in @Nature by Prashar et al. Selective degradation of mitocho….
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@osman_lab
OsmanLab
11 months
RT @RoussouRo: Grateful to everyone who contributed and beyond excited to share my work with you!.
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@osman_lab
OsmanLab
11 months
RT @VamsiMootha: Introducing a resource of mtDNA copy number (mtCN) across ~10k human donor-tissues (GTEx), 20 murine tissues, and 173 canc….
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@osman_lab
OsmanLab
11 months
RT @embojournal: Real-time assessment of yeast heteroplasmy dynamics at the single-cell level:.Asymmetric partitioning during cell division….
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@osman_lab
OsmanLab
11 months
RT @frank_pado: It was an absolute pleasure to collaborate on this, fantastic work lead by @RoussouRo. I'm very happy to see that our #Bioi….
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@osman_lab
OsmanLab
11 months
🚀Excited to share our latest paper, where we explore dynamic changes in mtDNA heteroplasmy in living cells! Discover how asymmetric partitioning and mitochondrial dynamics drive mtDNA variant segregation! 🔬#Mitochondria #microscopy #microfluidics #mtDNA.
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@osman_lab
OsmanLab
1 year
RT @langer_lab: Just wrapped up an amazing retreat at Schloss Ringberg🤩! With fantastic guest speakers/lab alumni, we enjoyed discussing al….
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@osman_lab
OsmanLab
1 year
RT @Ott_MitoLab: Just back from a wonderful retreat with the @osman_lab in Tjärnö on the Swedish west coast @GothenburgMBL. Three days of s….
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@osman_lab
OsmanLab
1 year
Awesome fun activity at the retreat with the @Ott_MitoLab at Tjärnö Marine Station 🔬🪸🪼🦀🦭
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@osman_lab
OsmanLab
1 year
RT @VamsiMootha: mtDNA heteroplasmy dynamics are so complex, even paradoxical. To understand why, we combined precise mtDNA editing w/a new….
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@osman_lab
OsmanLab
2 years
RT @demishassabis: Excited to share major progress on next generation of AlphaFold! Together with @IsomorphicLabs, we’ve significantly adva….
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@osman_lab
OsmanLab
2 years
Happy Halloween everyone!!! Thanks @DvaliTamara for organizing!!! Traditional pumpkin carving together with @MokranjacLab and Böttger labs! 🎃
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