🧬olivier namy🔬🧪🧫
@namyolivier
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director of research, biologist, president Section 21 #CNRS, #RNA and #ribosome fan, specialist in translation regulations at #I2BC @onamy.bsky.social
Joined December 2013
I am very proud to announce that our team has received an ERC synergy grant from @ERC_Research A wonderful recognition of a truly collaborative effort with friends (Julius Lukes, Leos Valasek and Mark Osborn). Excited to begin this scientific journey at @I2BCParisSaclay
The new 2025 ERC Synergy Grants will fund teams exploring: 🧬 how microbes could fix genetic diseases 💥 what happened moments after the Big Bang 🚶♂️ how crowds move and behave 🏔 how mountain societies adapt to change … and much more frontier science 👉 https://t.co/UZepClSkOl
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Nous vivons dans une ère où parler fort devient plus important que parler de faits. Je suis convaincu qu'on a besoin de plus de culture scientifique dans notre société. Pourquoi la culture scientifique est importante? Thread👇à partager pour plus de culture scientifique
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The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts.
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The time is ripe to substantially advance our understanding of translation. We can profile the diverse pool of modified tRNAs and a wider spectrum of amino acid incorporation into proteins: https://t.co/5XMPAq67qi The synergy of these developments will exciting ❗️ 1/2
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Hibernating ribosomes have a complex social life in starved yeast cells: they assemble into intricate clusters and bind to mitochondria, illustrating how ribosomes hibernate in their natural habitat. More—in this fascinating study by @jomaa_lab: https://t.co/wDSEkPPmRk
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So apparently there is m5C in bacterial tRNA 🦠 Stress-induced modification of Escherichia coli tRNA generates 5-methylcytidine in the variable loop | PNAS
pnas.org
There has been recent interest in trying to understand the connection between transfer RNA (tRNA) posttranscriptional modifications and changes in-...
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Online Now: Threonine-rich carboxyl-terminal extension drives aggregation of stalled polypeptides https://t.co/EkgQdRbqNs
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very happy to present our latest work on the diversity of RiboSeq signals associated with canonical and noncanonical translation! An almost 100% @i2bc paper with @BioCgpapado and @namyolivier published in @GenomeBiology ! https://t.co/xGkK7wbxUm
link.springer.com
Genome Biology - Pervasive translation is a widespread phenomenon that plays a critical role in the emergence of novel microproteins, but the diversity of translation patterns contributing to their...
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Les contours des sections du CoNRS vont changer https://t.co/nZYK7uXxj5 Création de deux sections supplémentaires, modification des périmètres de plusieurs autres sections, modification de l’intitulé de huit sections et nouvelle numérotation de toutes les sections. @CNRS
cnrs.fr
Début septembre 2025, le mandat des sections du Comité national de la recherche scientifique arrive à échéance.
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Nice to get good news from a publisher! Our review on quality control pathways working on #ribosome collisions has had over 3,000 views! If you want to learn all about ribosome collisions and how they are handled by cells check out:
chemistry-europe.onlinelibrary.wiley.com
The discovery of ribosome collisions as the recognition platform of translation problems caused by various factors represents a cornerstone in the field of translation surveillance. We summarize our...
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DENSE is out! Mine your genome and highlight its de novo genes :D
De Novo Emerged Gene Search in Eukaryotes with DENSE | @scoopit
https://t.co/HKA4qEMrkR
@anne__lopes @GenomeBiolEvol
#denovogenes
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The paper was published in @Nature and can be downloaded here:
nature.com
Nature - The structure of a human exosome–ribosome supercomplex reveals the mechanisms behind the formation of active cytoplasmic exosomes and their role in co-translational RNA decay.
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MicroRNA genes have evolved and expanded within the genomes of multicellular organisms for over 500 million years. Today, we know that there are more than a thousand genes for different microRNAs in humans, and that gene regulation by microRNA – discovered by this year’s
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RNA again! I did not believe miRNA would get it after siRNA. Pretty good for the field.
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR | @scoopit
scoop.it
TLN468 promotes PTC readthrough by preferentially incorporating specific tRNAs based on the mutation. Nonsense mutations account for 12 % of cystic fibrosis (CF) cases. The presence of a premature...
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We're excited to announce the publication of our latest study on the identification of a novel tRNA modification, 2-aminovaleramididine (ava2C), and its molecular basis on decoding. Congratulations and thanks to our wonderful collaborators! https://t.co/8mfHIcMeWj
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I recommend this thoughtful preview article highlighting our recent publication. Thank you @GertonJennifer @PaxtonKostos @anna_galligos for supporting our work! https://t.co/3xES92fvek
cell.com
In this issue of Cell Genomics, Rothschild et al. reveal how ribosomal RNA diversity impacts ribosome structure and its implications for health and disease. Their innovative methodologies uncover...
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I'm excited to share our latest review on mistranslation of the genetic code. I had a great time working with all the authors. A special shout-out to the talented @DBSchuntermann, whose creativity and determination were instrumental. https://t.co/mcXVPJCnFa
jbc.org
Transfer RNAs (tRNA) are essential small non-coding RNAs that enable the translation of genomic information into proteins in all life forms. The principal function of tRNAs is to bring amino acid...
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Le choc. 😶 En cette semaine de rentrée, voici très belle expérience #madeinfrance réalisée par l'agence @PublicisConseil pour le #SIG, le Service d'Information du @gouvernementFR. #actu #CultureCauses
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