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Payam A. Gammage Profile
Payam A. Gammage

@mito_oncogene

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Group Leader @CRUK_SI. Mitochondrial genetics, genome engineering, cancer metabolism. Lab supported by CRUK, ERC & NCI. EMBO 'Young' Investigator.

Glasgow, Scotland
Joined February 2019
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@mito_oncogene
Payam A. Gammage
8 months
P.s. Can’t recommend @EMBO_YIP enough - such an awesome programme. If you’re an eligible early group leader you should definitely think about applying - feel free to message me if you want advice!.
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@mito_oncogene
Payam A. Gammage
8 months
Headed home from @EMBO 60th Anniversary @embl Heidelberg & feeling grateful for an amazing few days, incredible presentations from across life sciences, new @EMBO_YIP friends, dinner in a castle (!) & inspirational talk from Katalin Karikó. Happy 60th bday @EMBO until next time!
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@mito_oncogene
Payam A. Gammage
9 months
What a bunch! A wealth of discovery and advances in this pan-journal collection of #CancerMetabolism articles to celebrate >100 yrs of Warburg - Cancer Metabolism 2.0. Humbled & grateful to see our lab’s work put in such exalted company 🙏.
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@mito_oncogene
Payam A. Gammage
9 months
This is so cool!! 😎(pun intended) - congratulations Pere @puigserver_lab @platorremuro and everyone else. Lovely work 🙏.
@puigserver_lab
Puigserver Lab
9 months
New paper by @platorremuro published in @CellCellPress! We combined thermoregulatory physiology, structural and computational approaches to determine the mechanisms of electron transfer and structural basis of respiratory complex adaptation to cold temperatures.
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@mito_oncogene
Payam A. Gammage
10 months
Congratulations Vanessa & @tommacvicar 👏👍 🙌.
@tommacvicar
Thomas MacVicar
10 months
Belated congratulations to postdoc Vanessa Xavier! She drove this project forward and built productive collaborations in the process - many thanks to all authors (1/3).
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@mito_oncogene
Payam A. Gammage
11 months
RT @sys_sig: We decided to readvertise our exciting paper 'Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologi….
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@mito_oncogene
Payam A. Gammage
11 months
This pre-print is a game changer for me. Finally, a satisfying and robust answer to the question of where and how mtDNA mutations arise and expand during ageing. Was my pleasure to examine Ali's thesis, on which it is based. @sys_sig @icmito .
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@mito_oncogene
Payam A. Gammage
1 year
Yes @echouchani !!! So deserved! Bravo!! 👏 👏 👏.
@echouchani
Ed Chouchani
1 year
I am thrilled and honored to join the @HHMINEWS community. So grateful to my lab, colleagues at @DanaFarber @HarvardCellBio, and collaborators whose work this reflects!.
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@mito_oncogene
Payam A. Gammage
1 year
RT @CR_AACR: Read the In the Spotlight commentary by Jose Enriquez and @MMittelbrunn, Warburg Effect Reshapes Tumor Immunogenicity, discuss….
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@mito_oncogene
Payam A. Gammage
1 year
For me this probably ranks as paper of the year so far. Bravely into no man’s land they went, emerging with a totally new and unparalleled method to impute metabolic data, including flux predictions, from RNA. It’s a huge achievement that can have far reaching impact. Bravo! 👏.
@EdReznik
Ed Reznik
1 year
A new preprint from our lab courtesy of the talented Amy Xie co-led w/Wes Tansey's group. It's a new method (UnitedMet) that does something very useful: give us RNA data, we give you metabolite levels and isotopologue distributions. Believe it.
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@mito_oncogene
Payam A. Gammage
1 year
Congratulations @EdReznik @SohrabShah @minsoo_kim1 - really great contribution to understanding of this murky intergenomic regulation. Fantastic work - I’m thrilled to have contributed to in a small way. Bravo! 🥳 #reznikonaroll.
@EdReznik
Ed Reznik
1 year
I thought my 2 year old was going through a sleep regression at 5 am, but no, he just wanted to let me know that our lab's newest work with @SohrabShah and led by Minsoo Kim was finally online @NatureGenet
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@mito_oncogene
Payam A. Gammage
1 year
As a former (briefly) neuroscientist, work like this bringing together mitochondrial physiology and neuronal function/basis of memory is super exciting to see and, in my small opinion, long overdue. Bravo @bergami_lab and all involved. Looking forward to your next works already!.
@bergami_lab
Bergami Lab
1 year
Our latest work is out in @NeuroCellPress! We show that a surge in dendritic mitochondrial fusion during the critical period is required for synaptic plasticity in adult-born neurons. Big thanks to @CRC_1218, @crc1451, @CECAD_ and @ERC_Research!.
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@mito_oncogene
Payam A. Gammage
1 year
Big opportunities in Glasgow for people wanting to set up an independent lab! Check it out 👇.
@KostasTokatlid
Kostas Tokatlidis
1 year
We're hiring @UofGSMB 4 positions (lecturer to Professor)Approaching deadline26/2/24 #Mitochondria, #proteostasis, #proteinfolding #signaling, #cellhomeostasis #UPR #proteintargeting @mitojobs @mitowomen @MRC_MBU @MitoResearch Fantastic interdisciplinary Mito cluster @UofGlasgow.
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@mito_oncogene
Payam A. Gammage
1 year
RT @CR_UK: Scientists at @CRUK_SI have found that certain mutations in cancer cells make them much more likely to respond to immunotherapy….
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@mito_oncogene
Payam A. Gammage
1 year
Just following up on our recent paper describing the role of recurrent mtDNA mutation in cancer - here are a couple of pieces, from @CRUKresearch and @NatureCancer, for the non-expert audience:.
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@mito_oncogene
Payam A. Gammage
1 year
As ever - if you would like to read an engaging, amusing and lucid tweetorial about our recent paper, @EdReznik’s is the one to go for 🙏.
@EdReznik
Ed Reznik
1 year
There comes a time in a PIs life where they rip free of the chains that bind them, and simply say all the things they want to say about a great paper. So here we go, a new paper driven by @mahnooorm and led by @mito_oncogene and I: Prepare to be annoyed.
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@mito_oncogene
Payam A. Gammage
1 year
@CRUK_SI @UofGCancerSci @mahnooorm @CRUKresearch @theNCI @ERC_Research @CR_Horizons @EMBO_YIP That feeling when you fail to add your science bro’s Twitter handle correctly 🙄@EdReznik.
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@mito_oncogene
Payam A. Gammage
1 year
RT @UofGMVLS: .@UofGlasgow scientists at the @CRUK_SIb have made an unusual discovery that could help to identify patients who are up to tw….
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@mito_oncogene
Payam A. Gammage
1 year
And that's a wrap. Huge thanks to everyone involved in the study, to our benevolent benefactors and of course to those helping us take this forward for patient benefit @CRUK_SI @UofGCancerSci @reznike @mahnooorm @CRUKresearch @theNCI @ERC_Research @CR_Horizons @EMBO_YIP 6/6.
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@mito_oncogene
Payam A. Gammage
1 year
While mtDNA mutation alone = modest survival increase in aggressive melanoma, changing cellular redox metabolism with cytoLbNOX = total tumour regression in 70% of subjects, w/ big increases in survival for escapees - a promising approach to sensitising tumours in the clinic🤞5/6
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