Taru Tukiainen
@ttukiainen
Followers
467
Following
213
Media
3
Statuses
140
Human Genomics @ University of Helsinki. PI, Senior Researcher, crazy dog mama, mum to two human beings.
Helsinki, Finland
Joined May 2013
Role of X chromosome and dosage-compensation mechanisms in complex trait genetics @ttukiainen & colleagues @GeneticsSociety members' research highlight from @AJHGNews
https://t.co/97UvOmj7sm
0
6
9
Genetic variation shapes reproductive traits – from gestational duration to menopause timing – influencing health across a woman’s life and into the next generation. 🧬 Join #GeneForum 2025 to find out more https://t.co/vndLv4LzhN
#Genetics #WomensHealth
0
2
8
@doctorveera This was a great paper! Glad the X is finally getting its due in complex trait work.
1
2
2
X chromosome dosage compensation through the lens of human genetics! Females have two X chromosomes, but males have one. To compensate for this, one X is randomly inactivated in female cells. Some genes escape from this inactivation. Because both males and females are
2
26
114
New work from my group out today in Cell Genomics. We found fascinating patterns of sex-biased gene expression in the human brain by comparing fetal and adult samples. Read more below 👇
Early establishment and life course stability of sex biases in the human brain transcriptome
0
2
7
📣Online now from @ttukiainen & co 📄Role of X chromosome and dosage-compensation mechanisms in complex trait genetics https://t.co/WdpvakK2EA
cell.com
We show that the X chromosome, understudied in genome-wide association studies, contributes to complex traits in a manner shaped by dosage-compensation mechanisms. We find near-full X inactivation...
0
2
13
Thrilled to share this update: Our work is now out in @AJHGNews
cell.com
We show that the X chromosome, understudied in genome-wide association studies, contributes to complex traits in a manner shaped by dosage-compensation mechanisms. We find near-full X inactivation...
Looking for weekend reading? I’m excited to share latest work from the group, a tour de force effort by the fantastic graduate student Yu Fu on the impact of chrX and dosage compensation on complex traits: https://t.co/uRDbluMI80
0
1
2
Looking for weekend reading? I’m excited to share latest work from the group, a tour de force effort by the fantastic graduate student Yu Fu on the impact of chrX and dosage compensation on complex traits: https://t.co/uRDbluMI80
biorxiv.org
The X chromosome (chrX) is often excluded from genome-wide association studies due to its unique biology complicating the analysis and interpretation of genetic data. Consequently, the influence of...
0
8
29
Thanks to all who have been part of this cool project! @ttukiainen Jaakko Leinonen Juha Riikonen and @MattiPirinen 🥰
1
1
2
Ylen uutinen Taru Tukiaisen ryhmän tuoreesta tutkimuksesta ⬇️ Lounaissuomalaiset ovat perimältään yhtä läheisiä virolaisten kuin kainuulaisten kanssa - Helsingin yliopiston tutkimuksessa saatiin uutta tietoa lounaissuomalaisten geeniperimästä. https://t.co/Phqw7XLIG9
yle.fi
Helsingin yliopiston tutkimuksessa saatiin uutta tietoa lounaissuomalaisten geeniperimästä.
0
1
2
Käy kurkkaamassa myös Anninan tekemät hienot kartat haploryhmien maantieteellisistä rikastumista Suomessa täältä:
zenodo.org
Y-chromosomal regional enrichment maps for all haplogroups with at least 1% frequency in Finland out of all samples. A star (*) within the map and gray color in the forest plot indicates the freque...
0
0
0
On oletettu, että Y-kromosomin I-haploryhmän kantajat ovat saapunut Suomeen lännestä ja N-haploryhmän idästä. Vastoin tätä perinteistä itä-länsijakoa tutkimuksessa löydettiin todisteita siitä, että N-haploryhmän kantajia on saapunut Suomeen sekä etelästä että idästä.
1
2
1
Turun Sanomat teki ison jutun meidän Y-kromosomilöydöksistä. Erityiskiitokset @AnninaPreussner ja Jaakko Leinoselle hienosta projektista. Työ liittyy @SuomenAkatemia rahoittamaan akatemiatutkijaprojektiin.
Turkulaiset poikkeavat muista suomalaisista aiempaa luultua enemmän: monen esi-isä tulikin Virosta
1
2
9
A little late to the game: I’m happy to share the latest work from the group where we elaborate on the origins of brain-related sex biases
biorxiv.org
To elaborate on the origins of the established male-female differences in several brain-related phenotypes, we assessed the patterns of transcriptomic sex biases in the developing and adult human...
0
2
5
Check out our latest findings on X-inactivation in iPSCs now out in Genome Biology https://t.co/SWpIukchnB A great collaboration with Dr Olli Pietiläinen and a cool demonstration of the many complexities of the X chromosome 😎
genomebiology.biomedcentral.com
Background Variation in X chromosome inactivation (XCI) in human-induced pluripotent stem cells (hiPSCs) can impact their ability to model biological sex biases. The gene-wise landscape of X chromo...
0
3
11
⏰ Tervetuloa tänään naisten terveyden iltaan Tiedekulmaan tai striimin ääreen klo 17! 🎥 https://t.co/oPu4cpCqIq Illan aiheina sukupuolikromosomien vaikutus terveyteen, synnyttäminen ja vaihdevuodet. @ttukiainen @FIMM_UH @helsinkiuni #terveys #tutkimus #tiede
0
3
2
Tervetuloa naisten terveyden iltaan Tiedekulmaan/striimin ääreen 9.4.! Illan aikana kuullaan tutkittua tietoa sukupuolikromosomien vaikutuksesta terveyteen, synnytyksestä sekä vaihdevuosista. https://t.co/hol2zad0Dd
@ttukiainen @FIMM_UH @HelsinkiUniMed @helsinkiuni #terveys
0
4
13
Excited to share our latest findings pointing to the more complex origins of the Y chromosomes in Finland than previously thought. Work led by the stellar @AnninaPreussner
biorxiv.org
The paternally inherited Y chromosome is highly informative of genetic ancestry, therefore making it useful in studies of population history. In Finland, two Y- chromosomal haplogroups reveal the...
0
4
18
A Mendelian Randomization study with 36,211 mother-child pairs indicates that maternal genetic variants, influencing a child's birth weight, impact the child's risk for common diseases through inheritance and not by effects on intrauterine growth. https://t.co/EPIHPDRz6c
nature.com
Communications Biology - A Mendelian Randomization study with 36,211 mother-child pairs indicates that maternal genetic variants, influencing a child’s birth weight, impact the child’s...
1
1
5