Taru Tukiainen
@ttukiainen
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Human Genomics @ University of Helsinki. PI, Senior Researcher, crazy dog mama, mum to two human beings.
Helsinki, Finland
Joined May 2013
RT @genomicstartu: Genetic variation shapes reproductive traits – from gestational duration to menopause timing – influencing health across….
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RT @stetson_thacker: @doctorveera This was a great paper! Glad the X is finally getting its due in complex trait work.
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RT @doctorveera: X chromosome dosage compensation through the lens of human genetics!. Females have two X chromosomes, but males have one.….
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New work from my group out today in Cell Genomics. We found fascinating patterns of sex-biased gene expression in the human brain by comparing fetal and adult samples. Read more below 👇.
Early establishment and life course stability of sex biases in the human brain transcriptome
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RT @AJHGNews: 📣Online now from @ttukiainen & co.📄Role of X chromosome and dosage-compensation mechanisms in complex trait genetics. https://….
cell.com
We show that the X chromosome, understudied in genome-wide association studies, contributes to complex traits in a manner shaped by dosage-compensation mechanisms. We find near-full X inactivation...
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Thrilled to share this update: Our work is now out in @AJHGNews
cell.com
We show that the X chromosome, understudied in genome-wide association studies, contributes to complex traits in a manner shaped by dosage-compensation mechanisms. We find near-full X inactivation...
Looking for weekend reading? I’m excited to share latest work from the group, a tour de force effort by the fantastic graduate student Yu Fu on the impact of chrX and dosage compensation on complex traits:.
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Looking for weekend reading? I’m excited to share latest work from the group, a tour de force effort by the fantastic graduate student Yu Fu on the impact of chrX and dosage compensation on complex traits:.
biorxiv.org
The X chromosome (chrX) is often excluded from genome-wide association studies due to its unique biology complicating the analysis and interpretation of genetic data. Consequently, the influence of...
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RT @AnninaPreussner: Thanks to all who have been part of this cool project! @ttukiainen Jaakko Leinonen Juha Riikonen and @MattiPirinen 🥰.
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RT @FIMM_UH: Ylen uutinen Taru Tukiaisen ryhmän tuoreesta tutkimuksesta ⬇️. Lounaissuomalaiset ovat perimältään yhtä läheisiä virolaisten k….
yle.fi
Helsingin yliopiston tutkimuksessa saatiin uutta tietoa lounaissuomalaisten geeniperimästä.
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Käy kurkkaamassa myös Anninan tekemät hienot kartat haploryhmien maantieteellisistä rikastumista Suomessa täältä:
zenodo.org
Y-chromosomal regional enrichment maps for all haplogroups with at least 1% frequency in Finland out of all samples. A star (*) within the map and gray color in the forest plot indicates the freque...
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RT @FIMM_UH: On oletettu, että Y-kromosomin I-haploryhmän kantajat ovat saapunut Suomeen lännestä ja N-haploryhmän idästä. Vastoin tätä per….
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Turun Sanomat teki ison jutun meidän Y-kromosomilöydöksistä. Erityiskiitokset @AnninaPreussner ja Jaakko Leinoselle hienosta projektista. Työ liittyy @SuomenAkatemia rahoittamaan akatemiatutkijaprojektiin.
Turkulaiset poikkeavat muista suomalaisista aiempaa luultua enemmän: monen esi-isä tulikin Virosta
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A little late to the game: I’m happy to share the latest work from the group where we elaborate on the origins of brain-related sex biases
biorxiv.org
To elaborate on the origins of the established male-female differences in several brain-related phenotypes, we assessed the patterns of transcriptomic sex biases in the developing and adult human...
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Check out our latest findings on X-inactivation in iPSCs now out in Genome Biology A great collaboration with Dr Olli Pietiläinen and a cool demonstration of the many complexities of the X chromosome 😎.
genomebiology.biomedcentral.com
Background Variation in X chromosome inactivation (XCI) in human-induced pluripotent stem cells (hiPSCs) can impact their ability to model biological sex biases. The gene-wise landscape of X chromo...
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RT @tiedekulma: ⏰ Tervetuloa tänään naisten terveyden iltaan Tiedekulmaan tai striimin ääreen klo 17! . 🎥 Illan ai….
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RT @tiedekulma: Tervetuloa naisten terveyden iltaan Tiedekulmaan/striimin ääreen 9.4.! Illan aikana kuullaan tutkittua tietoa sukupuolikrom….
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Excited to share our latest findings pointing to the more complex origins of the Y chromosomes in Finland than previously thought. Work led by the stellar @AnninaPreussner
biorxiv.org
The paternally inherited Y chromosome is highly informative of genetic ancestry, therefore making it useful in studies of population history. In Finland, two Y- chromosomal haplogroups reveal the...
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RT @CommsBio: A Mendelian Randomization study with 36,211 mother-child pairs indicates that maternal genetic variants, influencing a child'….
nature.com
Communications Biology - A Mendelian Randomization study with 36,211 mother-child pairs indicates that maternal genetic variants, influencing a child’s birth weight, impact the child’s...
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Thanks to Jaakko for the hard work, the two reviewers for the excellent feedback, @FinnGen_FI for the amazing data, @SigridJuselius and @HiLIFE_helsinki for the funding.
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