In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @NatureHumBehav 💰🧬🎓 Link: https://t.co/Q5wAbt2B46 Thread below 👇🏽

Check out our new paper on the genetics of educational fields in @NatureGenet Open access link: https://t.co/zDaSyCkfpo

A Love Letter to Social Science Genetics https://t.co/u2AyVOrR5z by @dr_appie

Nice commentary by @fctropf reflecting on our study on not having sex: https://t.co/54StfcyFUQ (for full study, see quoted tweet below)

What do you do when you're call blasting Bigfoot in eastern Washington, a pool of mysterious blood shows up in your tent and you can't find any answers? You call in Dr. @SimeonHein and his remote viewers. Then, for verification, you call in Intuitive TishPaquette at the

Population-specific polygenic risk scores for people of Han Chinese ancestry Published today in Nature. Three authors from Genomic Prediction: Hsu, Raben, and Widen Dataset is Taiwan Precision Medicine Initiative (N~500k). I believe it is the largest dataset of non-European

This was truly fascinating to read

🧬💥 Do the genetics that make you develop a disease also help you survive it? Not much. Our new @NatureGenet including 9 disease and 7 biobanks shows: • Susceptibility variants ≠ survival • PRSs for onset weak at predicting survival • Lifespan PRS predicts survival better

Your body speaks truth. Your brain tells stories. TWO SYSTEMS running your life — end the war. Watch. Touch a leaf. Heal.

🚨 New preprint out! We reconstructed parental haplotypes in >440k individuals (UK & Estonian biobanks) to estimate assortative mating directly in the parental generation. This reveals intensified assortment in recent generations. 🔗 https://t.co/wnag6TiWWo

We are excited to share GPN-Star, a cost-effective, biologically grounded genomic language modeling framework that achieves state-of-the-art performance across a wide range of variant effect prediction tasks relevant to human genetics. https://t.co/FTm3byYp67 (1/n)

Why do some people never have #sex, even later in life? A new study, conducted by @amsterdamumc and @UQ_News alongside researchers of our Institute, explores this fascinating question. Check out the @PNASNews paper here:  https://t.co/em2qUk5irY @laurawesseldijk #Sexlessness

Here is our new preprint ( https://t.co/dbRy3KLs27). We report heritability estimates for multiple traits using a within-family design in 500,000 sibling pairs of diverse ancestries! Fantastic collaboration with @23andMeResearch! Thanks to their participants and research team.

Excited to share our preprint on PGI portability across ancestries—now on bioRxiv. With co-authors @AysuOkbay, @patrickaturley, @AlexTISYoung, @Dan_J_Benjamin. Preprint: https://t.co/FhNDxY55CC Thread below for details.

@laurawesseldijk Brendan Zietsch wrote a good and accessible summary of our paper here:

Many thanks to my co–first author @laurawesseldijk (🥰), co–last authors Brendan Zietsch & Karin Verweij, and all other co-authors ❤️ Check out the paper here:

Sexlessness is relevant to wellbeing and evolution. But it’s also a complex behavioral trait: its genetic associations trace back to many other traits and environments. The associations we find are correlational and likely to be culture-specific, so more research is needed.

Genes linked to sexlessness overlap with genes associated with: - Higher education & IQ - Less substance use - Higher autism & anorexia risk - Lower ADHD, anxiety, depression & PTSD risk

Thousands of genetic variants with very tiny effects together explain ~15% of variation. The genetic correlation between men and women is .56. Ancient DNA shows an allele significantly associated with sexlessness declined over 12,000 years, consistent with natural selection.

Where you live matters too. Men in regions with fewer women were more likely to be sexless. Sexlessness was also more common in regions with higher income inequality.

Sexless individuals reported: - More loneliness, nervousness, unhappiness - Fewer close relationships & social connections - Less alcohol & drug use Patterns differed by sex: for men, physical strength, income, and social connection mattered more.

Sex is central to human wellbeing. ~1% of people never have sex. While some people simply don’t want sex, for others, no partner can mean loneliness, lower wellbeing, or even economic disadvantage. No sex is also interesting for genetics as it is an evolutionary “dead end”.

The largest study on late life virginity, based on > 400k individuals, out now in @PNASNews Open access link: https://t.co/v9FsYzaOqg Shoutout to shared first author @laurawesseldijk ❤️ Thread below 👇🏽