Abdel Abdellaoui
@dr_appie
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Complex Trait Genetics | Population Genetics | Evolutionary Genetics | @AmsterdamUMC | @UvA_Amsterdam
Amsterdam, The Netherlands
Joined July 2015
Did you get a chance to read the thread on our new @NatureHumBehav paper on SES yet?. If not, don't worry, I have something better for you!. Check out this comic by the amazing @Lizah_Aart. The complete comic here: You can also scroll this thread 👇🏾
In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @NatureHumBehav 💰🧬🎓. Link: Thread below 👇🏽
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RT @Lizah_Aart: Yayy that’s all scicomm talks done! Thank you for hosting me at Amsterdam @dr_appie
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RT @TabeaSchoeler: 🚨New preprint is out!.How do genetic effects on complex traits change with age?. In this work, we compare different appr….
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RT @Lizah_Aart: How does art contribute to science?.My friend Eliza Wolfson and I 'talked' about this in a comic!.I'm preparing some lectur….
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RT @MinSeoKim_MD: Delighted to share the preprint on the largest obesity GWAS to date!. GWAS from >2 million participants. Key:.✳️13% incre….
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RT @EvolvedBiofilm: July issue of @TrendsMicrobiol is now online, with our review by Xinming Xu @neftalyl @CajaDinesen @AdelePioppi on Comp….
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RT @Lizah_Aart: When I illustrate a journal cover I try to also create a version of that illustration in a format that would work as a powe….
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I'm in London in a couple of weeks giving a special lecture for the London Genetics Network @LdnGeneNet 🇬🇧. The event is open to members of the London Genetics Network, who can sign up here:
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Anyone have any feedback on this yet? . New and hopefully improved version coming soon! 🎲🧬.
I'm developing a strategic 1-on-1 game called Base Pair™ – based on biologically accurate rules 🧬🎲. Want to play and give feedback? Reply to this tweet (or RT), and I might send you a free handmade beta copy! . (I have a limited nr right now, but more are on the way)
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RT @hilsomartin: New preprint - collab with the groups of @mehurles and @dr_appie. We imputed missing fluid intelligence test scores into ~….
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RT @koenfucius: Research by @_david_berg et al improves the usefulness of the UK Biobank (450,000 individuals) in understanding the genetic….
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RT @harpersnotes: intel. genetics, more data suggesting rare variants depress (fail to support), so many mostly small hits to general intel….
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RT @namankatyal14: making visual representation of research works in comic book style. Genius. Each page was informative and reading about….
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RT @hsu_steve: Another great paper by Abdel and collaborators. If only we had more data - biobanks should obtain cognitive phenotypes for a….
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Thanks to all the co-authors for a wonderful collaboration between scientists from @sangerinstitute and @amsterdamumc, especially lead authors @_David_Berg, Wei Huang, @DMalawsky, @mehurles, and @hilsomartin! ❤️.
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By expanding the dataset of fluid intelligence scores, we show that imputation can reveal biology that would otherwise be missed, especially for rare variant analyses. A general summary & FAQ with accessible explanations are available in the Supplement:
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Many of the rare variants influence cognition even in people without a clinical diagnosis. This supports the idea that neurodevelopmental disorder genes often act along a spectrum, and can influence cognitive function below diagnostic thresholds.
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