Michael Lin, MD PhD 🧬
@michaelzlin
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Professor of Neurobiology & Bioengineering @Stanford ☘️🧪🦠🧠🌈🔬📖🇺🇲🌏Neurons, viruses, medicines. Invented predecessor of Paxlovid. Also @MichaelLinLab
Harvard→UCLA→HMS→UCSD→Stanford
Joined July 2015
Click the thread below to get to my SARS-CoV-2 mega-metathread. That thread previously had its own intro tweet, but I deleted it by mistake. This being Twitter, there are no free undos. So instead this tweet will parachute you into it.
First, a link to the COVID-19 metathread of 2020-2021.
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At this point, I'd be happy if someone wanted to spend more time at his resort golfing.
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RT @michaeldweiss: This type of obsequiousness is eventually followed by hysterical confessions of crimes one did not commit.
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Restraint is the mark of security.
Not hard to see how he bankrupted so many casinos. These are the same rooms btw.
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RT @CyFi10: BREAKING: California reports COVID positivity SKYROCKETS to 15.9% in the Bay Area, higher than 2023, and 2024! .
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All throughout, the article make you wonder, if Vance was so disappointed in GWB from his time in Iraq, how did he not end up in Democratic politics? Maybe that wasn't his main motivation, perhaps other issues such as cultural ones made him throw his hat into the GOP ring?.
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Very interesting read about JD Vance. Clearly thoughtful and intelligent in his criticism of GW Bush's Iraq misadventure, but that independent spirit doesn't seem to have extended to a particular later President's exaggerations and untruths.
politico.com
The vice president’s four years in the Marine Corps planted the seeds of his populism — and his pursuit of power.
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"In this context and consistent with Canada's commitment to USMCA, I am announcing today that the Canadian government will now match the United States by removing all of Canada's tariffs on U.S. goods specifically covered under USMCA," he said.
reuters.com
Canada will remove many retaliatory import tariffs on U.S. goods and intensify contacts with the United States on striking a new trade and security relationship, Prime Minister Mark Carney said on...
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RT @davidsirota: This is an interesting story, but also some DC brain rot. There's no split among Dem voters. Polling is clear: Dem voters'….
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The man, the myth, the legend— at least, that’s what Kinta wants to be… . Catch the final arc of DAN DA DAN Season 2, now streaming!.
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Maybe Democratic party leaders will finally realize that raising money from billionaires isn't going to help at the ballot box.
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Pediatricians are the most chill docs; it takes a lot to get them into sassy mode. Yet FDA managed to do that.
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Good article on the AAP recommendations, which I forgot to mention just came out today.
arstechnica.com
The American Academy of Pediatrics recommends children under age 2 get vaccinated.
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Oh I had forgotten that humans are supposed to be useless at summarizing publicly available information now that we have AI. Let's see if Grok can do better. @grok can you summarize the current status of COVID-19 vaccines in the US?.
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If you want to see the EU approvals, here they are. Note no wording about risk groups, just simple ages approved for each vaccine. So yes the FDA is making it more complicated than necessary, and not saying the truth about it.
ema.europa.eu
The European Medicines Agency (EMA) evaluates and recommends the authorisation of medicines marketed in the European Union (EU). This includes COVID-19 vaccines and treatments. Although COVID-19 in...
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In the EU you can just get it, no questions asked. Here in the US you have to go through the additional hoop of asserting your child is at-risk. But if you needed any help convincing your doctor, you can choose from this official list published in that NEJM piece above
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Would you trade 10 years of labor and residence for a roundtrip to our Moon?.
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The EMA approves the vaccines for everyone ≥6mo, and public health agencies then actively recommend it for those at risk. So it's more like everyone can get it, and we especially recommend it for those at risk. That's different from the drug not being approved for low-risk!.
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Prasad and Makary attempted to justify the new FDA policies in a NEJM opinion piece by saying that SARSCoV2 vaccines are only recommended in the EU for older adults and at-risk people of other ages. However this argument is misinformed or disingenuous.
nejm.org
This article from the FDA compares broad U.S. recommendations on Covid vaccination with those from other countries and announces the adoption of an evidence-based approach to such recommendations.
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Thus it's terrible medical practice for FDA to only officially approve COVID vaccines for kids ≤5mo if they are at "higher risk". That age is at especially higher risk!.
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In any case, kids <2yo are at higher risk of complications than older kids, because their next SARSCoV2 infection is more likely to be their first, and thus they have no preexisting active immunity from the myriad cardiovascular, pulmonary, and neurological issues that can arise.
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Novavax has filed for LP.8.1 in Japan, not sure if they will do LP.8.1 or parental JN.1 in the US (they had shown LP.8.1 boosters weren't better and might even be overspecialized to LP.8.1 vs other JN.1 substrains, below from .
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Anyway adding to uncertainty is that FDA has been slow to approve the 2025-2026 formulations. They had recommended a JN.1 lineage, preferably LP.8.1, and all 3 manufacturers made LP.8.1 shots. Pfizer and Moderna have made it past the EU's CHMP already.
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Always curious and full of energy, Beagles turn every walk into an adventure 🐾🎉.
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