Summary of que 3️⃣ moderated by @GLiperis #ESHREjc

Summary of que 4⃣ moderated by @DKalaitzopoulos #ESHREjc

Summary of que 2️⃣ moderated by @juanjo_fraire #ESHREjc

Summary of que 1️⃣ moderated by @AttilioDGM7 #ESHREjc

November #ESHREjc is done and dusted thanks to our experts and authors for joining us! And kudos to our moderators! See you all in January 🌟

@OmarRawi89 See you next time! #ESHREjc

@OmarRawi89 Many thanks to our experts and author 🙌 #ESHREjc

Many thanks to all participants 🙌 and to @OmarRawi89 and his team for leading this great edition of the #ESHREjc

Q4: #ESHREjc Until prospective data arrive, what’s a proportionate counseling message for TTC/IVF patients needing analgesia, what alternatives, what timing advice, and how to avoid over-restriction that drives unsafe NSAID substitution? @ESHRE

Q3 #ESHREjc Given emerging evidence of sperm-borne epigenetic and RNA cargo effects on early development, should we test whether paternal acetaminophen use around conception affects embryo dynamics/implantation & how would we design feasible human& animal studies? #ESHRE

Q2: #ESHREjc Nielsen et al, showed the molecular effect of APAP 💊 on early embryogenesis. However, we cannot exclude its systemic effect. Could APAP also affect endometrial tissue during implantation? Would its effects extend beyond the peri-implantation period? @ESHRE

🚨Q1 #ESHREjc The study finds that APAP delays cleavage-stage divisions, while blastocysts keep total cells but show reduced ICM and DNA synthesis. What do these stage-specific vulnerabilities imply for implantation and embryo competence? @ESHRE

@OmarRawi89 @NoemiSalme30386 @Saara_riibeiro @FabrizzioHorta @juanjo_fraire @GLiperis @atylio @DKalaitzopoulos @juliauraji @OmarRawi89 will be the lead moderator of this #ESHREjc – thank you Omar, the floor is all yours 😊

@OmarRawi89 @NoemiSalme30386 @Saara_riibeiro @FabrizzioHorta @juanjo_fraire @GLiperis @atylio @DKalaitzopoulos @juliauraji A quick reminder of the housekeeping essentials before starting 👇 1. Use the hashtag #ESHREjc in all your tweets related to the journal club 2. The #ESHREjc will start now until tomorrow 29 November 17.00 CET 🕔 3. Please always comment in the thread of the questions

@OmarRawi89 @NoemiSalme30386 @Saara_riibeiro @FabrizzioHorta @juanjo_fraire @GLiperis @atylio @DKalaitzopoulos We’d also like to welcome our experts @juliauraji and Thanos Papathanasiou and author David Kirstensen #ESHREjc

@OmarRawi89 @NoemiSalme30386 @Saara_riibeiro @FabrizzioHorta @juanjo_fraire @GLiperis @atylio @DKalaitzopoulos

Welcome to this month's #ESHREjc moderators 🙌 Have fun! @OmarRawi89 @NoemiSalme30386 @Saara_riibeiro @FabrizzioHorta

For those who have not had the chance to read the paper our moderators have created a great tweetorial 👉 https://t.co/cNb5wnsinh #ESHREjc

This edition’s paper is “Paracetamol (N-acetyl-para-aminophenol) disrupts early embryogenesis by cell cycle inhibition” published in our science journal Human Reproduction 👩‍🎓 🔗 https://t.co/JmZvjzHkg7 #ESHREjc

Welcome everyone, we are back for the 49th edition of the #ESHREjc 🙌