Daniel Ezzat
@daniel_ezt
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BAEF Research Fellow at Massachusetts General Hospital and Broad Institute of MIT and Harvard
Cambridge, Massachusetts
Joined December 2022
Thrilled to share that our study is out now in @ESC_Journals #EJPC! We examined long-term outcomes after coronary angiography among >5,000 individuals with measured lipoprotein(a) [Lp(a)] — one of the most important yet under-recognized drivers of atherosclerotic disease 🫀
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Excited to share our work @ESC_Journals #EJPC led by @KelvinS_MD @CFAndersenMD w/ @aklfahed Lp(a) + post-cath outcomes in 5,118 🧑🤝🧑 undergoing cor angio 🫀 @MGHHeartHealth : Lp(a) >=175 nmol/L ➡️ ⬆️ subsequent MI, revasc, ISR, need for PCI after CABG https://t.co/hc0pdKOdky
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So grateful for my mentor’s unwavering support and thank you @AHAScience for the opportunity to present our study, an effort to understand atherosclerosis, its trajectory, and disease localization 🫀🧬🏃
At the Elizabeth Barrett-Connor Research Award for Early Career Investigators #AHA25 @KelvinS_MD shares our work on why people have atherosclerosis in different vascular beds (coronary, cerebrovascular, and peripheral). https://t.co/LbkugqUufY
@MGHHeartHealth @broadinstitute
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Our analysis of CHIP (clonal hematopoiesis of indeterminate potential) and risk of heart failure in ~420,000 @uk_biobank participants led by rising ⭐️ @Sflynn4242 @mghmedres now in @JAMACardio simultaneous w/ #AHA25
https://t.co/OBTznjschl (1/4)
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📢 #JACCばらん Ep.30「CHIPping the Code: CHIPと心血管リスクの交差点」 🎙️ゲスト：井上 峻輔 先生 @Geno_shun （東京大学大学院 医学系研究科 先端循環器医科学講座 🇯🇵／Editorial執筆） 🔍 今回は Clonal Hematopoiesis of Indeterminate Potential（CHIP） にフォーカス。
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Please join us in congratulating @mchonig!! 👏#weheartourteam
Major congrats to @mchonig with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ https://t.co/QNE0mRPIEJ
@JACCJournals 2️⃣ https://t.co/lL4U3LogL6
@JACCJournals 3️⃣ https://t.co/oNKAAftAwl
@JAMACardio
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Low-Dose Colchicine May Slow Growth of Clonal Hematopoiesis - American College of Cardiology @NiekMohamma
acc.org
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Wonderful exchange of science and terrific lectures by @mchonig @MassGenBrigham and @Borjaibanez1 @CNIC_CARDIO at the 8th MGB transatlantic dialogues @BrighamWomens @RonBlankstein
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Fantastic presentation by rising star MGB Heart and Vascular Institute cardiologist @mchonig at the 7th MGB Transatlantic Dialogues meeting at @CNIC_CARDIO with major cardiology legends in attendance! #ESC2025 @MGHHeartHealth @mghcvrc @MGHWomenHeart @broadinstitute @harvardmed
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So proud of these 3 for their simultaneous pubs with #ESCCongress2025 @escardio
@daniel_ezt @JACCJournals ( https://t.co/iTZGizylr2)
@NiekMohamma @JACCJournals ( https://t.co/9dTKXPWM01)
@artschuermans @JAMACardio ( https://t.co/Zd9gMIHcdX)
Major congrats to @mchonig with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ https://t.co/QNE0mRPIEJ
@JACCJournals 2️⃣ https://t.co/lL4U3LogL6
@JACCJournals 3️⃣ https://t.co/oNKAAftAwl
@JAMACardio
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In the special session of research on women/ sex differences includes a trial related to autoimmune disease 📍autoimmune disease associated with ⤴️ CVD risk (35%) 📍some traditional risk factors not as strongly associated with CVD in those with Autoimmune diseases 📍T2DM & CKD
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Major congrats to @mchonig with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ https://t.co/QNE0mRPIEJ
@JACCJournals 2️⃣ https://t.co/lL4U3LogL6
@JACCJournals 3️⃣ https://t.co/oNKAAftAwl
@JAMACardio
jamanetwork.com
This study tests whether clonal hematopoiesis of indeterminate potential is associated with the development of myocarditis and pericarditis.
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Among middle-aged adults, clonal hematopoiesis of indeterminate potential (CHIP) was linked to an increased risk of developing myocarditis and pericarditis. 🧵 #ESCCongress #WCCardio
https://t.co/5OcuKJVKPr
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Does clonal hematopoiesis of indeterminate potential (CHIP) predict heart inflammation? Thrilled to share our work identifying CHIP as a risk factor for myo-/pericarditis, with the amazing @mchonig Simultaneous pub with #ESC2025 in @JAMACardio
https://t.co/GFroe0r7wE (1/x)
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Editorial: Schuermans et al's study links clonal hematopoiesis (CHIP) to acute inflammatory heart conditions, suggesting that CHIP mutations could serve as key biomarkers for predisposition to chronic and acute cardiac diseases. #ESCCongress #WCCardio
https://t.co/hQ4HsYBGZB
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New report that CHIP (clonal hematopoiesis of indeterminate potential, blood stem cell clones that increase with age) is an independent risk factor for myocarditis and pericarditis, promoting inflammation #ESC2025 @JAMA_current
https://t.co/spxhWqXqNH
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Longitudinal analysis of the LoDoCo2 clinical trial suggests that colchicine blunts TET2 CHIP expansion possibly mediated by reductions in IL-6! These results add to a growing body of evidence that colchicine and IL-6R blockers may be beneficial for CHIP-associated CVD...
In this exploratory analysis, Tx w/ low-dose colchicine was assoc w/ an attenuated annual clonal growth in TET2 CH. Findings suggest potential for colchicine to curb proliferative advantage of key CH driver mutations https://t.co/QipRX2Dn6U
#ESCCongress #WCCardio #JACC @mchonig
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@daniel_ezt presenting his work simultaneously published in @JACCJournals #JACC at #ESC2025 @escardio
https://t.co/iTZGizylr2
The lab's first sim pub of #ESC2025 is now online in @JACCJournals #JACC ! https://t.co/iTZGizylr2 Led by 🇧🇪⭐️ @daniel_ezt , we examined clonal hematopoiesis (CHIP) 🩸 & cardiovascular 🫀 outcomes in older women 👵 using deep targeted 🧬 sequencing in the @WHIStudy 👇 (1/X)
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