Marc-André Legault
@legaultmarc
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Assistant prof at @pharm_umontreal and @CR_CHUSJ. Genetic epi, causal inference and ML.
Montreal, Qc
Joined March 2009
Tenure track position opening in Brest, France, in statistical genomics ! Come and join us to work with our team at UMR1078 on the development of multiomics data analysis. https://t.co/6kGNxUSPRv
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McGill is cancelling job searches due to tuition cuts by Quebec government on all English language universities. Dreadful decision by government having bad effects already.
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2023 IGES Annual Meeting starts in 9 days! 🧬 Take advantage of activities targeted for early career investigators: - gathering during welcome reception, Nov 5 - mentoring lunch, Nov 6 - social hour, Nov 7 Please repost, share, advertise. See you in Nashville! @genepisociety
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Awesome thread about an IV study looking at shingles and dementia
Biggest thing to ever come out of my little group. Pls help spread this finding! We found clean, CAUSAL evidence that the shingles vaccine prevents a good chunk of dementia cases. So, could a virus cause Alzheimer’s->YES! Hear me out & see preprint: https://t.co/25f5XFQj8R 🧵1/
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Biggest thing to ever come out of my little group. Pls help spread this finding! We found clean, CAUSAL evidence that the shingles vaccine prevents a good chunk of dementia cases. So, could a virus cause Alzheimer’s->YES! Hear me out & see preprint: https://t.co/25f5XFQj8R 🧵1/
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I'll be speaking tomorrow at @RealAAAI on the challenges of using Reinforcement Learning in Precision Drug Dosing. Joint work with Doina Precup, @adri_romsor and @legaultmarc When: 9th Feb, 11:15-12:30AM Where: 202B See you there! #AAAI23 #AAAI #AI #ArtificialIntelligence
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Hello World! I am Herbert and I am a dinosaur of computer art. This year I will have my 95th birthday. My first (still analog) computer art originates from 1954. Much more art work followed till now ...
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Researchers from @bdi_oxford have taken a major step towards mapping the entirety of genetic relationships among humans: a single genealogy that traces the ancestry of all of us. Watch the estimated geographic locations of ancestors of multiple samples over time. ⬇️
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CLeaR conference submission deadline is on Oct 22nd 11:59pm anywhere on earth. Looking forward to seeing your work there!
Interested in causality? Check out the 1st Causal Learning and Reasoning (CLeaR) conference! Paper submission deadline is Oct 22nd, see our website https://t.co/yGZWILRjtb for details. Looking forward to the conference!
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incredible paper! Proteomics of adult and embryonic hearts shows female hearts express different set of proteins than male hearts, and KO of one these impairs cardiac physiology only in females. Awesome work from @fconlon and Ileana Cristea's labs
cell.com
Male/female differences in cardiac function and disease have been attributed to hormonal differences. In this paper, though transcriptomic and proteomic analyses in mice, Shi et al. find that cardiac...
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New paper out from @juhussin lab! Congrats to Isabel Gamache for that fabulous work! Another step to better understand genes evolution and their link with cardio-vascular phenotypes! A sex-specific evolutionary interaction between ADCY9 and CETP
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What happens when a high impact journal published something which was subject to a high profile retraction? Still cited months later -- and data is even used in secondary analyses. Need a systems approach to dealing with retracted work https://t.co/9JEVrjsAoD
@DrEmilyMcD
jamanetwork.com
This quality improvement study examines the continued citations of a widely publicized retracted article on COVID-19.
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Science is like a chicken coop: Talk given earlier this month at @sortecoevo conference. Reform is hard, and simple narratives about incentives do not help, because incentives are not simple.
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Amazing case report. The medicine of tomorrow. 5 week old boy admitted to NICU. Within 37 hours he had his whole genome sequenced, gene defect identified, treatment ordered and received by patient. Within 6 hr symptoms resolved. https://t.co/UYSJSURQHW
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Forget chess and go. What about Dixit as the next grand AI challenge? https://t.co/4WxEB4Ly0s (authors don't appear to be on twitter)
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New preprint from @juhussin lab, in collaboration with @jctardif_mhi
@MP_Dube and @soumya_boston. Check it out now!
A sex-specific evolutionary interaction between ADCY9 and CETP https://t.co/4ZhMe2voCr
#bioRxiv
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ExPheWas: a browser for gene-based pheWAS associations https://t.co/mazfn529mO
#medRxiv
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Mapping the human genetic architecture of COVID-19 by worldwide meta-analysis https://t.co/uRWxprfkxL
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Really delighted that our piece on Mendelian randomization 🧬 applied to therapeutic targets & the contradistinction with MR of conventional biomarkers is now online at @NatRevCardiol Many thanks to an all 💫 cast including @iTomRichardson @nm_davies & @mendel_random
New #Review on Integrating genomics with #biomarkers and therapeutic targets to invigorate #cardiovascular drug development by Michael Holmes and colleagues. https://t.co/Vqt2yzg0VS
#drugdiscovery #Genomics #MendelianRandomisation #bioinformatics
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Many of the COVID-19 genetic efforts focus on the risk of infection and severity of disease. Here we took a different perspective: duration of symptoms in 1723 outpatients https://t.co/mky7rjgS4M
medrxiv.org
We conducted a genome-wide association study of time to remission of COVID-19 symptoms in 1723 outpatients with at least one risk factor for disease severity from the COLCORONA clinical trial. We...
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