1/n A webinar from @CDC_Genomics on Mendelian randomization (MR) highlights some under-appreciated aspects of MR; this thread outlines these

Want to understand epidemiology? You can study for an MSc for 2 years, but this entertaining presentation by George Davey Smith @mendel_random provides the essentials in 45 min. He also reveals crucial issues that university programs don't teach.

In which I bang on about all the usual stuff, with the thread being managing to stay alive

In which I bang on about all the usual stuff, with the thread being managing to stay alive

🏅 Congratulations George Davey Smith, our Scientific Director, on winning @The_MRC Millennium Medal! 🧬 For exceptional contributions to improving human health through world-class medical research 👉 Read more: https://t.co/XP4mKm96NF

Why guess when you can know?

This is a cool idea. However, the claims made about the MR analysis (SOD2 -> cardiac fibrosis) are just... wierd, and not really novel, and sort of show a lack of understanding of how MR and GWAS work. the authors claim ("Discovery 4: SOD2 as a driver of cardiac fibrosis") +

Honoured to receive the 25th Anniversary MRC Millenium Medal. My mid-1980s epidemiological apprenticeship was at the MRC Epidemiology Unit in Cardiff in the mid-1980s, and my senescence with the MRC IEU, closing in March 2028 🙏 MRC! https://t.co/b261WST3NJ

"The China question is not one of capability. It is one of restoring trust in the ethical conduct of its medical science." In this Editor's Choice, @KamranAbbasi writes on the relentless rise of China’s medical science https://t.co/yNUMtoShC4

This letter was not published in the Times Sir, The European Study of Prostate Cancer Screening after 23 years follow up, demonstrated an excess of 27/1000 prostate cancers in the screened group compared with the untested controls. Mortality from prostate cancer was 1.4% in the

How is SG, a services and finance hub in Asia, supporting the region's corporates and governments in their transition to a low-carbon future?

Thrilled to announce the official publication of my new book — The Mechanic and the Luddite: A Ruthless Criticism of Technology and Capitalism Grab my book to go beyond the vaporous hype and get the real material analysis of technological capitalism that we all need!

Moreover, thanks to Prof. Shigang He, you can study allostasis in Chinese!

Sorry forgot the link for this, here it is

Mendelian randomization (MR) was partly a response to the epidemiological studies suggesting vitamins were protective against various diseases, only for randomised trials to be null. Fallacious MR attempting to resurrect the spurious claims discussed here

📷 "Triangulation: moving from correlations to causes", Cambridge School of Clinical Medicine Distinguished Lecture 2025, Thursday, October 16th, 5pm, in person or online

“The litany of factors that epidemiological studies promoted as being likely protective, with subsequent disappointment as RCT findings were reported, has kept growing—high-density lipoprotein cholesterol, beta carotene, vitamin C, vitamin A, selenium and vitamin D, among others”

The British establishment have all ready covered this new Banksy up. Can we get it Retweeted 10,000 times to show that they can never cover up their complicity in war crimes?? Protect the right to protest! RT!

Mendelian randomization (MR) was partly a response to the epidemiological studies suggesting vitamins were protective against various diseases, only for randomised trials to be null. Fallacious MR attempting to resurrect the spurious claims discussed here

Labour party members, think of this when voting for a deputy leader

🎉 Huge congratulations to @amymariemason – voted Most Popular Mathematician in I’m a Mathematician 2025! 🏆 She’s taken part in 28+ live Chats, sharing her work, challenges, and passion for maths with students across the UK. 💬 Read more about it here:

America’s demand for energy is rising and we have the abundant resources right here at home to meet that need. It’s time to unleash American energy and reform the broken permitting process now.

Investigating potential causal effects of maternal smoking on offspring handedness using a proxy gene-by-environment (GxE) Mendelian randomization design out today: https://t.co/g5cee8QOrW with Daisy Crick @mendel_random @medland_sarah

2/n according to @yudapearl application of the front door criteria will become a "serious competitor to RCTs". To make such claims he must, surely, have some evidence to support it. Can he please provide one (1 single) example of how this competitor has performed in this regard?