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Kipnis Lab Profile
Kipnis Lab

@kipnislab

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We like all things #neuroimmune!

St Louis, MO
Joined August 2019
Don't wanna be here? Send us removal request.
@kipnislab
Kipnis Lab
6 years
In science, the days are long but the years are short.
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@Fusion_Conf
Fusion Conferences
1 year
@kipnislab we are looking forward to your presentation at #TargetAD25 in Crete next May🇬🇷☀️Registration & Talk Submission is now OPEN so please RT to let your followers know! Find out more: https://t.co/UnjcdFajPX
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@EricTopol
Eric Topol
1 year
New @Nature An unanticipated discovery: the brain suppresses the immune response by producing autoimmune "guardian peptides" that block neuroinflammation, which may be especially important in neurodegenerative diseases https://t.co/wbdi7kxHCQ Important work by @jonykipnis
nature.com
Nature - Central nervous system (CNS)-derived regulatory self-peptides are essential for maintaining a continuous dialogue between the CNS and the immune system while balancing overt autoreactivity.
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@ImmunoPodcast
Immunology Podcast
11 months
How is the #CNS protected from the immune system? @MitchKim_MW and a team in the @KipnisLab found that regulatory self-peptides bind to MCH II molecules at the central nervous system border. @Nature paper: https://t.co/POjXUnpJax Discussion: https://t.co/y9iZAmjy17
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@jonykipnis
Jonathan Kipnis 💔🎗️
1 year
Excited to share a new work from @kipnislab by amazing Wenqing Gao (twitter-less) on developing engineered T cell therapy for CNS injury ||
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nature.com
Nature - This study presents a new T cell therapy targeting spinal cord injury, providing a potential new approach for injured CNS.
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@kipnislab
Kipnis Lab
1 year
We are very proud of @DuSiling for wining the best poster prize at @WashUdbb @WUSTLImmuno retreat! Congrats, Siling! The story is amazing and you are very deserving of this recognition!
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@DuSiling
Siling Du
1 year
🧵 Excited to share my first preprint from my PhD @kipnislab and @TheColonnaLab: "Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia." 🧠🦴 https://t.co/czMqzFmKXz
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biorxiv.org
Microglia are thought to originate exclusively from primitive macrophage progenitors in the yolk sac (YS) and to persist throughout life without much contribution from definitive hematopoiesis. Here,...
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@castel_giulia
Giulia Castellani
2 years
Our Spotlight on the groundbreaking work of @lcdsmyth, @jonykipnis, @kipnislab and colleagues is out in @TrendsImmuno. 🧠💡 Thanks to #JavierMaríaPeraltaRamos and #MichalSchwartz.
@TrendsImmuno
Trends in Immunology
2 years
Bridging anatomical gaps between brain and immune system https://t.co/q8EIXETGvt #immunology
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@kipnislab
Kipnis Lab
2 years
Excited that this conference is coming to us! Amazing lineup of speakers! Please register and RT!
@jonykipnis
Jonathan Kipnis 💔🎗️
2 years
Excited to co-host another amazing conference #ReThinkNeuroimmunology together with @IdoAmitLab. This time we are hosting @WUSTLmed @WUSTL. Registration site is now open. Please register asap. Number of seats is limited. https://t.co/K6zsSRp6We
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@jonykipnis
Jonathan Kipnis 💔🎗️
2 years
In 1992 @SciAM article, Carla Shatz summarized Hebb’s theory as “Neurons that fire together wire together”. Today, inspired by Carla's phrase, we bring you “Neurons that fire together shower together”. Why do we sleep? Why to we emit waves? @neurobenjamin attempted to answer
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@washumedicine
WashU Medicine
2 years
WashU Medicine researchers are uncovering sleep’s role in maintaining brain health. Rhythmic waves associated with restful sleep help to propel waste and toxins away from the brain. Learn more:
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medicine.washu.edu
Findings could lead to new approaches for Alzheimer’s, other neurological conditions
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@neurobenjamin
Li-Feng Jiang-Xie
2 years
Excited to share our work published today. We identified that neurons are the master organizers for brain fluid perfusion and waste clearance. Inspired by Hebbian rule and Carla Shatz’s phrase, we summarize it as 'neurons fire together shower together'. https://t.co/Yc7W2RKGhk
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@Nature
nature
2 years
Nature research paper: Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance
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@Nature
nature
2 years
Active neurons can stimulate the clearance of their own metabolic waste by driving changes to ion gradients in the surrounding fluid and by promoting the pulsation of nearby blood vessels
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nature.com
Nature - Neurons stimulate the brain's waste disposal system.
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@IshmailSaboor
Ishmail Abdus-Saboor
2 years
This paper from @jonykipnis lab is incredible. Striking results that have updated how I think about what neural activity in the brain is actually doing - especially during sleep or anesthesia. Elegant approaches and easy-to-follow and compelling writing. https://t.co/zIAHvnWkft
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@felipe_pinh0
Felipe A Pinho Ribeiro
2 years
Absolutely honored to join the CZI community and thrilled to embark on this with the one and only @jonykipnis. This joint effort is set to push the boundaries of neuroscience and advance brain health. Grateful and excited for what's ahead! #neuroimmunology #makingADifference
@cziscience
CZI Science
2 years
We’re excited to support 64 interdisciplinary teams that are taking innovative approaches to study fundamental #neuroscience + neurodegenerative diseases. Read more about our second cycle of @ChanZuckerberg’s Neuroscience Collaborative Pairs Pilot Projects
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@NatRevImmunol
Nature Rev Immunol
2 years
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases https://t.co/nPlehXgGBg
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@tischfield
Max Tischfield
2 years
Thank you to @matrongolo, @d0ctorphil, Aditya Jain, Akash Reddy, Gaetan Barbet, Young-Kwon Hong, Junbing Wu, and rest of the team for their hard work + dedication to this study🙏👏 this is a very exciting field for those interested in opportunities (DM me), and much more to come!
@jclinicalinvest
Journal of Clinical Investigation
2 years
Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice: https://t.co/DKrIiDhSK4 @tischfield @Rutgers_NJMS #Neuroscience #VascularBiology
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@lcdsmyth
Leon Smyth
2 years
We're excited to share these tools with the scientific community to enable a more precise dissection of the functions of different CNS fibroblast types. Dpp4-CreERT2 targets arachnoid barrier cells, while Slc47a1-CreERT2 targets dural border cells.
@jonykipnis
Jonathan Kipnis 💔🎗️
2 years
A delivery of @lcdsmyth’s strains from his recent paper to Jax is being finalized. We already have the strain numbers and I hope they will soon be available to the scientific community to explore the menigeal (and other) fibroblasts! Stock No. 039217 Dpp4-CreERT2 Stock No.
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@jonykipnis
Jonathan Kipnis 💔🎗️
2 years
Super excited for this award for our collaborative project with @felipe_pinh0. But even more excited to join this exceptional group of scientists and can't wait for the in-person meeting to meet everyone and to brainstorm!
@cziscience
CZI Science
2 years
We’re excited to support 64 interdisciplinary teams that are taking innovative approaches to study fundamental #neuroscience + neurodegenerative diseases. Read more about our second cycle of @ChanZuckerberg’s Neuroscience Collaborative Pairs Pilot Projects
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@washumedicine
WashU Medicine
2 years
How does fluid waste leave the brain? A new study by #WashUMed uncovers the passageways that carry waste away from the brain, offering potential therapeutic targets for neurodegenerative diseases:
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medicine.washu.edu
Discovered route serves as passageway to clear fluid waste from brain
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