
Karla Kaun
@karlakaun
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From the way-up 🇨🇦 North. Now @BrownUNeuro looking at how memories are made and how alcohol and drugs of abuse influence this.
Brown University
Joined August 2010
Addiction has a genetic basis – not just in how certain genes can influence the risk of developing a substance use disorder, but also in how alcohol and drugs themselves can change how your genes work.
theconversation.com
Improved understanding of the molecular mechanisms of addiction can change how researchers and clinicians approach treatments.
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RT @CarneyInstitute: Whether it's talking with students, reporters, or policymakers about addiction - @BrownUniversity neuroscientist @kar….
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RT @Brown_SPH: “We need to demonstrate that the science we do matters. That means getting out of our academic bubbles.”. Professor @ChrisKa….
carney.brown.edu
Karla Kaun argues that addiction researchers should talk about their work in their everyday lives. Those conversations can shape how drug, tobacco and alcohol use is studied in labs, taught in...
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Omar Abubaker, Eric Nestler and I spoke about how science brings hope for those suffering from alcohol and substance use disorders at an Advocacy forum @SfNtweets #SfN24. Our message is that as scientists we need to be better at communicating this.
A challenge for basic scientists is to guarantee that the future generation of health-care professionals and policymakers understands the importance of addiction and mental health research. By Omar Abubaker, Karla Kaun @karlakaun, @EricJNestler.
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RT @SfNtweets: Join past SfN President Eric Nestler,MD, PhD, and other leading experts at the #SfN24 Advocacy Forum to address the multifac….
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RT @KristinScaplen: Thrilled to get started on this work with the fantastic undergraduates @BryantUniv @BryantUHealth!! Thanks to the @NIAA….
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RT @bess_frost: @CarneyInstitute @BrownMedicine We’ll be holding an open search for faculty at all ranks focused on investigating mechanism….
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@CSHLflycourse @neurofly2024 If you've ever thought about adding flies to your scientific program, I'd encourage you to give it a try! Fly behavior experiments are fun, accessible and you can't beat the amazing genetic tools available. If you have questions and ideas for posts I'd love to hear them!.
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@CSHLflycourse @neurofly2024 Lots of variables contribute to the outcome of #Drosophila behavior experiments. Could your mood be influencing your results? imo HELL YES. Create a routine to stabilize your mood before you start your behavior experiments.
kaunlab.com
This is probably one of my most controversial opinions, but I think that the mood of a person can affect the outcome of an experiment. To be clear, this is entirely based on speculation on my part...
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@CSHLflycourse @neurofly2024 Automatically tracking behavior in #Drosophila does not have to be expensive. How do you build your own simple tracking system? Build an arena, buy a camera with an IR filter, build an IR backlight, set up a controller and choose tracking software.
kaunlab.com
One of the nice things about working with flies is that you can build a simple, cost-efficient tracking system pretty easily. In the lab we’ve built both inexpensive and expensive tracking systems,...
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@CSHLflycourse @neurofly2024 A lot of speciality items are used for building #Drosophila behavior equipment. What materials should you use and where can you get them? We buy acrylics and lasercut and assemble most of our equipment. Find our favorite suppliers and materials here:
kaunlab.com
We use lots of specialty items in building Drosophila behavior arenas and tracking systems, but sometimes it’s difficult to know where to get all of these pieces. When you are building an apparatus,...
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@CSHLflycourse @neurofly2024 Anesthesia can affect #Drosophila behavior, even after the flies are awake. How long can you leave flies anesthetized and how long should you wait before performing behavior? <5 min on CO2 and let the flies recover for 2 days before your experiment.
kaunlab.com
As you probably know, carbon dioxide (CO2) is the most popular anesthesia for fly pushing. It immobilizes flies quickly and flies wake up shortly after being removed from anesthesia seemingly...
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@CSHLflycourse @neurofly2024 Fly food is important for #Drosophila rearing, and has profound impacts on behavior. So what is the best recipe to use for behavior experiments? It probably doesn’t matter as long as your food is nutritious, and consistent between vials and over time.
kaunlab.com
Which fly food recipe should I use to raise flies for behavior
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@CSHLflycourse @neurofly2024 Most of what we know about #Drosophila behavior comes from lab experiments 🧪. So how do flies behave in their natural environment? They search for food, hide from predators and are ‘social butterflies’ on rotting fruits and veggies.
kaunlab.com
I grew up in pretty remote areas and spent a lot of my youth out in nature watching animals (especially insects). That being said, I know embarrassingly little about what Drosophila really do in the...
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@CSHLflycourse @neurofly2024 Did you know that scientists have been studying #Drosophila behavior as long as flies have been studied in the lab? From William E. Castle > Thomas Hunt Morgan > Jerry Hirsch > Seymour Benzer, behavior has always been important to understanding genetics.
kaunlab.com
As someone that has worked on fly behavior for many years, I’ve become more and more fascinated with the beginnings of the field. It always amazes me how serendipitous science is, and how outside...
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AS @CSHLflycourse winds down and we get excited for @neurofly2024, I thought it might be helpful to post a few highlights. You can find a longer 🧵 on 🦋.
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I’ve studied the neural and molecular mechanisms of behavior using #Drosophila for over 20 years, and over my sabbatical I put together a list of questions, tips, and tricks that might be helpful for those entering the world of fly behavior. 🧵.
kaunlab.com
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RT @drosophilosophy: find the lie. go ahead. i dare you. i'll wait. @karlakaun speaks nothing but the truth.
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RT @andrew_c_lin: Check out our new review about sensory coding in the fly mushroom body, with @MosheParnas and @JManoim ! .
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My favorite line from our editorial "Overall, technological advances in neuroscience follow a repetitive pattern: If you wish to know where brain science in general will be in the future, you might look at what #Drosophila researchers are doing now." 🪰🧠😈💅.
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RT @TeleseFrancesca: A big THANK YOU to @IBANGStweets for honoring me with the 2024 Early Career Achievement Award at the Genes, Brain, Beh….
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