Jason Tchieu
@jtchieu
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Assistant Professor @ Cincinnati Children's Hospital Medical Center and member of the Center for Stem Cell and Organoid Medicine.
Cincinnati, OH
Joined May 2009
So happy to see it published! Thanks to all collaborators @studerl @daph_cabi @MendenMichael @bstockwell @gabriele_ciceri @jtchieu and all others!
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https://t.co/OdeuCwmPx8 Congrats Richard and team for a great paper!
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great time @ISSCR meeting #ISSCR2023 Looking forward to @Takebelab ISSCR Outstanding Young Investigator Award presentation tomorrow. Faculty positions available @CuSTOMOrganoids https://t.co/fv76fh3tud Join Taka @JimWellsLab @Zornlab @MingxiaGu, @Jtchieu et al @CincyChildrens
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Our Schwann cell paper is out! Huge thank you to the entire team who made this possible, especially @FaranakFattahi and @studerl. The review and editorial processes at @CellStemCell took our study to a new level 😎 I cannot wait for you to check it out! https://t.co/fFsS0xRMd1
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Want to further your career in biomedical science? We're accepting applications soon for our next class!
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Organoids move one step closer to human kidneys #NBTintheNews via @GENbio
genengnews.com
A highly efficient method generates differentiation of hPSCs into ureteric bud (UB) organoids which mature into the adult kidney.
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Thrilled to share the preprint ( https://t.co/2KNRDv0Vs0) of our work to understand key regulators of lung epithelial progenitors using in vitro organoids and in vivo mouse models as a large part of my thesis in @DrWillZacharias lab.
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I am excited to share my @TEDTalks at #TED2022 on how lab-grown neural cells and circuits can contribute to reverse engineering human brain development & uncover the biology of neuropsychiatric disorders https://t.co/DSms3crkYs
#assembloids #organoids #brain #Mentalhealth
ted.com
Neuroscientist Sergiu P. Pasca has made it his life's work to understand how the human brain builds itself -- and what makes it susceptible to disease. In a mind-blowing talk laden with breakthrough...
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Ever wonder how Wnt/beta-catenin can activate so many different genes in different cellular contexts? @_smukherjee @ZornLab @CuSTOMOrganoids @MDBCincy show in @CellReports that SOX Transcription factors are the key.
cell.com
Mukherjee et al. show that during WNT-induced differentiation of human pluripotent stem cells, SOX transcription factors can recruit β-catenin to lineage-specific enhancers independent of TCFs, the...
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Exciting opportunity in stem cell biology! The Center for Stem Cell Biology @MSK_CSCB @MSKCancerCenter has an ongoing search for new tenure track faculty. Deadline is October 17, 2022. For more info see https://t.co/JjUbZAyIoy or contact me directly at studerl@mskcc.org.
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Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex | Nature Neuroscience
nature.com
Nature Neuroscience - Dong et al. show that proliferative neural progenitors in the developing neocortex preferentially undergo anaerobic glycolysis and generate a high level of lactate that...
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Here we go again! We are looking for a Postdoc interested in hematopoietic stem cell biology and microenvironment to join our lab ( https://t.co/8je1Ugok0T) in Chicago. Please retweet or apply below! @UICPharmacology
pinholab.com
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Millay lab @CincyChildrens has multiple positions available for postdocs or research scientists. Therapeutic strategies for neuromuscular diseases, biochemistry of cell fusion, muscle multinucleation, or any ideas we think up together! DM me and please RT! #myotwitter
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Important new preprint on cell fate sequences and cortical development (@fumio_matsuzaki et al., looking at ferret 🧠) “Single cell transcriptomics of ferrets reveal a common temporal pattern of #progenitors in #brain development of #gyrencephalic mammals” https://t.co/pPYiaiOW7B
biorxiv.org
The diversity of neural stem cells is a hallmark of gyrencephalic brains, including that in humans. Ferrets are an excellent model to study the complex brain development in gyrencephalic mammals, but...
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Using Stem Cell Models to Explore the Genetics Underlying Psychiatric Disorders: Linking Risk Variants, Genes, and Biology in Brain Disease
psychiatryonline.org
There is an urgent and unmet need to advance our ability to translate genetic studies of psychiatric disorders into clinically actionable information, which could transform diagnostics and even one...
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We are excited to expand our research program! Research positions (graduate/postdoc/associates) are available to investigate cardiac and neurodevelopmental disorders. Please contact if you're interested. https://t.co/h7ZLe2JTTg
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Grateful to be selected for the 2022 ISSCR Achievement Award https://t.co/mFwhv1XQ3Q Thanks to all the trainees @sloankettering @MSK_CSCB and all the colleagues who made the work possible. Congrats to other 2022 ISSCR awardees @CreminsLab @SJMorrison_ and Joanna.
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Very excited to share 3D Live-Seq. Integrated live-cell imaging and single-cell DNAseq of the same tumor #organoids. We reconstruct evolving tumor genomes over multiple consecutive cell divisions to map the tempo and patterns of karyotype diversification https://t.co/FPGaP48eck
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