We also built an Shinyapp interface that allows everyone to access our single cell and spatial datasets easily: https://t.co/zLUncXUfxZ We envision our datasets will serve as a resource will provide insights for the cardiac and regeneration/fibrosis fields in the future!

Huge thanks to my PI Dominic @dominic_grun , my friends/colleagues in the lab, and all my collaborators who shared their efforts and dedication over these years!! This 5 year-journey wouldn’t have been successful without you all! 🙏

Excited to share our new paper “Spatiotemporal dynamics of the cardioimmune niche during lesion repair” just published in Nature Cardiovascular Research! https://t.co/8S6IdFxpcd

Online Now! Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling https://t.co/GSA0pzpL8J #stemcells

Potato evolved from tomato 9 million years ago. https://t.co/YZ2PSYtJns @NHM_London Sandra Knapp @UBC Loren H. Rieseberg @SCUCN Jianquan Liu #CAAS Sanwen Huang @cellcellpress

New preprint from the lab! Using multiplexed spatial analysis and single-cell multiomics, we resolved the portal liver immune niche and identified crosstalk between cholangiocytes, dendritic cells and gdT cells controlling fibrosis in a cholangitis model. https://t.co/bclOnqiuKa

This is effectively a cure for type 1 diabetes. Autologous, (chemically) reprogrammed iPSCs were engineered from a patient's fat cells and injected back into her stomach. After ~2.5 months, she no longer needed insulin and now enjoys ice cream + candy like a normal person.

BREAKING: MIT just completed the first brain scan study of ChatGPT users & the results are terrifying. Turns out, AI isn't making us more productive. It's making us cognitively bankrupt. Here's what 4 months of data revealed: (hint: we've been measuring productivity all wrong)

My lab at @WeizmannScience was completely demolished by the Iranian missile a few days ago. This is hard and sad as nothing was left to save. We study heart regeneration and regenerative medicine. As such, we will regenerate, regrow and rebuild. The one thing that wasn't gone is

A visual–omics foundation model to bridge histopathology with spatial transcriptomics https://t.co/r6PdyMEHkg

Deep in the ocean… 📹AI

Developmental onset of planarian whole-body regeneration depends on axis reset: Current Biology

NEW STUDY: Senolytic molecules that clear aged cells (like dasatinib + quercetin), slow age-related hearing loss in mice by protecting cochlear cells & reducing inflammation. You heard it here 🧵

Extremely happy to share our study on the regulation of HSCs in the context of myocardial infarction! Driven by two amazing scientists in my lab - Jasmin and Maricarmen and co-led with the awesome cardiologist Timo! Huge thanks to all our collaborators 👏🏻👏🏻 @mpi_ie @ETH_en

Random question: In human brain, consciousness emerges from the neuron’s collective activity, despite no single neuron is conscious. Similarly, society comes from many individuals working together. Could collective consciousness also emerge at the societal level, as in the brain?

Our paper plus the cover in @CellSystemsCP on cardiac fibrosis. A novel insight on these pathologies with some therapeutic solutions.

Perturb-FISH, a method that combines high-throughput imaging spatial transcriptomics with in situ guide RNA detection, allows for the analysis of molecular and functional states, with spatial resolution at the single-cell level @CellCellPress https://t.co/4BpKb0y9dy

Research| Secco et al. present the CycleTrack genetic tracing method to visualise cardiomyocyte turnover in neonatal and adult mice, after myocardial infarction, and upon pro-regenerative stimulation. https://t.co/UF5RcPbASS 👉 https://t.co/Kzm3uqVbqE @GiaccaMauro

Check out this nice "Tools of the Trade" piece in @NatureRevGenet by Ankit Agrawal on our NiCo algorithm for the analysis of single-cell spatial transcriptomics data from platforms like Xenium, MERSCOPE, seqFISH etc. Feel free to reach out for advice. https://t.co/TW1GWzngFs

Super excited to share that our manuscript is finally OUT @CellSystems!!🚨 Cold and hot fibrosis define clinically distinct cardiac pathologies. https://t.co/pZhWBCyPtG🧵(1/)