Among Kenyan health care workers surveyed, 43.1% met criteria for major depression during at least one assessment over 12 months. https://t.co/A6Vvcuh9Lw

Primary care treatment of #PTSD with either SSRIs or written exposure therapy (WET) was found to be feasible and effective; for patients not responding to an #SSRI, switching to an SNRI may be more effective than WET augmentation. https://t.co/BvKyDKPY12

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Neuropsychiatric disorders impose a substantial burden on individuals and societies worldwide. 📢 This Special Communications reflects the broad consensus of experts to advance the agenda for precision psychiatry. https://t.co/HD9NEyDc33

This case-control study found that adults with schizophrenia had significantly greater frontal cortex serotonin release than healthy controls, and greater release correlated with more severe negative symptoms. https://t.co/K4CCsPsJxv

This Viewpoint describes the mental health burden experienced by Muslim populations exposed to war and discrimination and recommends strategies for mental health services to address this burden. https://t.co/2txe2uX77z

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In a male Swedish cohort, higher IQ at age 18 was associated with reduced risk of alcohol use disorder, and genetic analyses support a causal link with cognitive performance, though the association varied by sociocultural context. https://t.co/Zgxvuu5mED

Liafensine was efficacious and well tolerated in ANK3-positive patients with treatment-resistant depression, highlighting ANK3 as a predictive genetic biomarker for liafensine. https://t.co/6hy5jUTBrQ

Viewpoint: Heavy alcohol use is a public health issue, prompting the Alcohol Clinical Trials Initiative to advocate for @WHO risk drinking level reduction as a dynamic treatment endpoint in AUD trials to facilitate new medication development. https://t.co/EUimOWrURy

💬 Viewpoint: Muscarinic receptor activators, such as xanomeline-trospium, offer an alternative mechanism for treating #schizophrenia, with potential benefits for positive, negative, and cognitive symptoms. https://t.co/MD2rga9IE9

Among adults with substance use disorder (#SUD), heart rate variability biofeedback reduced negative affect, craving, and substance use, suggesting it may be an effective adjunctive, low-cost treatment for SUD. https://t.co/VUtzUKKaPQ

Antipsychotic use among US adults aged 65 years or older increased by 51.6% from 2015 to 2024, with long-term use rising 64.9%. https://t.co/aZZbhbdV3B

Alcohol use disorder (AUD) is a prevalent and costly psychiatric disorder. This Review examines the use of reductions in World Health Organization (WHO) risk drinking levels as an end point in pharmacotherapy trials for people with alcohol use disorder. https://t.co/nb30iNniVG

Early dose reduction or discontinuation after remission from first-episode psychosis increased short-term relapse and lowered quality of life but yielded better researcher-rated functioning at 3 and 4 years. https://t.co/hAsXrLhC6Z

This Viewpoint describes the mental health burden experienced by Muslim populations exposed to war and discrimination and recommends strategies for mental health services to address this burden. https://t.co/QfQxtikPqm

📢 This Special Communication recommends hybrid survey designs—combining online panels with probability samples—as a new standard for psychiatric epidemiological research. https://t.co/R31x7fyEbE

Brief cognitive behavioral therapy significantly reduced suicide attempts among US military personnel and veterans compared to present-centered therapy. https://t.co/t2KeK3pcFR

In a male Swedish cohort, higher IQ at age 18 was associated with reduced risk of alcohol use disorder, and genetic analyses support a causal link with cognitive performance, though the association varied by sociocultural context. https://t.co/eueVWWAuji

Among adults with substance use disorder (#SUD), heart rate variability biofeedback reduced negative affect, craving, and substance use, suggesting it may be an effective adjunctive, low-cost treatment for SUD. https://t.co/7ESKM3GHwh

#Semaglutide reduced HbA1c and body weight over 26 weeks in individuals with #schizophrenia spectrum disorders and early glycemic abnormalities taking clozapine or olanzapine. https://t.co/aYMuuSKr4G

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💬 Viewpoint: Xanomeline-trospium offers a dopamine-independent approach to schizophrenia care. Clinicians should discuss potential impacts of dopamine blockers on motivation and quality of life. https://t.co/HB2XlXpXPn