Enfu Hui
@hui_enfu
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Professor @UCSanDiego @ucsdbiosciences Biologist, husband, dad, nerd š¤, and š¾ fan.
UC San Diego
Joined August 2015
Thrilled to share our @SciImmunology paper! Rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. Kudos to @MasubuchiTakeya for leading
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RT @immunologyUCSD: The Program in Immunology welcomes Dr. Joseph Sun.@SunLab_Official .from.@MSKCancerCenter.and.@WeillCornell. Please joiā¦.
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RT @takaki_komiyama: 663 days since the senseless tragedy that took An, we present a manuscript that reports some of the discoveries that sā¦.
biorxiv.org
During the execution of learned motor skills, the neural population in the layer 2/3 (L2/3) of the primary motor cortex (M1) expresses a reproducible spatiotemporal activity pattern. It is debated...
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RT @Dushek: Our work by Anna Huhn @annagesine is now published @NatureComms !. We show that the antigen contributesā¦.
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RT @SciImmunology: Scientists have identified functional differences between human and mouse #PD1, which could impact preclinical researchā¦.
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RT @MasubuchiTakeya: Excited to share our latest paper describing the functional divergence of PD-1 across species. Thank you for @hui_enfuā¦.
today.ucsd.edu
Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is signific...
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RT @ucsdbiosciences: Today in Science Immunology: Much of our knowledge of PD-1, a leading cancer target, comes from studies in mice. @UCSaā¦.
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RT @LabWaggoner: A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity.@SciImmunolā¦.
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RT @WallaceUcsf: Delighted to share our new preprint on the cell biology and genome of Stentor pyriformis, a giant ciliate that maintainsā¦.
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RT @LiGanLab: Excited to share our work, new in @ScienceMagazine: We explored how sex chromosomes, gonadal hormoneā¦.
science.org
Alzheimerās disease (AD) and other age-related disorders associated with demyelination exhibit sex differences. In this work, we used single-nuclei transcriptomics to dissect the contributions of sex...
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RT @Ulrike_Boehm: š¬ Are you eager to dive into the world of light microscopy and learn from top-notch microscopists about its essential tecā¦.
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RT @Cell_Metabolism: #NewIssue On the cover: In this issue of Cell Metabolism, Li et al. reveal that sick neurons release lipids to the gliā¦.
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THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA | PNAS
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P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPĪ± and facilitates macrophage evasion by Borrelia burgdorferi
biorxiv.org
Innate immunity, the first line of defense against pathogens, relies on efficient elimination of invading agents by phagocytes. In the co-evolution of host and pathogen, pathogens developed mechani...
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RT @immunologyUCSD: The Program in Immunology congratulates Professors Sue Kaech @Tcellogic and Steve Hedrick on their election to the Natiā¦.
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RT @Tcellogic: Hi all, what is happening to foreign scientists in Florida is horrible. Pls Join and donate to AAPI orgs in Florida to helpā¦.
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RT @StimulatedRaman: Collaborating with Dr. Xu Chen @xuashleychen1 Dr. Yajuan Li, MD PhD imaged brain microglial lipid droplets accumulatiā¦.
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RT @xuashleychen1: Excited to share our work @Cell_Metabolism: What happens when sick neurons dump fat to glia? We saw it by eye using @Stiā¦.
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