🧪Move over CUT&Tag, there’s a new #TranscriptionFactor mapping method in town. Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag. 🔗 Our @natcomms.nature.com paper: 🧵Here’s why DynaTag is so powerful(1/7)

This fascinating new #JIPB review by Iswanto et al. highlights work on #TranscriptionFactor engineering that has led to improvement in #growth performance, #yield and immunity, focusing on changes in #plant architecture related to improved yield and #disease resistance.

Gee WIZ! Impressive tour de force by NIBR scientists who found and DRUGGED a novel #TranscriptionFactor for fetal hemoglobin (HbF) induction for #SickleCellDisease . Phenotypic #drugdiscovery is legit! 😉#ASH23

With diverse experience & perspectives, our team is uniquely positioned to collectively explore all angles of the #transcriptionfactor therapeutics problem, accelerating breakthroughs & developing solutions faster. ⬇️ More from Co-founder & CTO, @lkpino ⬇️. #TeamMassSpec

📗From PCP latest issue: Review💐.’Are complex traits underpinned by polygenic molecular traits? A reflection on the complexity of gene expression'.Mohsen Hajheidari et al. #ComplexTraits #TranscriptionFactor #Plantsci

Targeting transcription factors: Talus Bio Co-Founder & CEO @afederation shares how we're advancing a first-in-class small molecule inhibitor of #brachyury for initial use in the spinal cord cancer #chordoma. #transcriptionfactor #cancerresearch

Bringing therapeutic breakthroughs within reach requires an integrative technological approach. That's why our MARMOT platform combines several technologies to discover first-in-class treatments for diseases caused by #transcriptionfactor dysregulation, like #cancer.

#SCENIC+. Single-cell/-nucleus transcriptome + chromatin accessibility▶️.eRegulon/enhancer-driven regulon.🤠Gene Regulatory Network based on >30k #TranscriptionFactor motifs from 29 databases. GRN velocity for differentiation trajectories. #EvoDevo at TF level. @steinaerts

ATAC-Seq analysis using geneXplain #geneexpression #Bioinformatics #generegulation #genomics #Transfac #Analytics #transcriptionfactor

TF Binding Mapped via DynaTag in Single Cells, Low-Input Samples. A new physiological salt-based method enables high-resolution transcription factor mapping in small and single-cell samples.@UniCologne.#transcriptionfactor #lungcancer #geneexpression.

Advances in transcription factor delivery: Target selection, engineering strategies, and delivery platforms. | In-San Kim @KISTKOREA | @KoreaCRS .[Open Access].#TranscriptionFactor #CellReprogramming .

The Talus Bio team left the @asmsnews Asilomar conference inspired by the #massspectrometry advancements of the last few years & ready to drive the next generation of #transcriptionfactor therapeutics. Pictured: @lkpino & @wfondrie presenting their research ⬇️

A great way to dive into the complexity of plant #transcriptionfactor functions and regulation without drowning. Decoding the functionality of plant transcription factors

What is known about the current molecular mode of action of GLKs? Molecular Action of GOLDEN2-LIKE Transcription Factor Family with Diverse Interacting Promoters and Proteins #plantscience #GLK #transcriptionfactor #promoter

The eighth (parallel) mini symposium of #IBS2023 navigated themes in "#SystemsBiology". Chaired by #SudhaRajamani, it featured talks by:.- @rsidd120.- @shaon_chak.- @shankarmukherji. #TranscriptionFactor #chromatin #CellFate #cancer #organelle #heterogeneity #growth @IMScChennai

A key discovery was that the NK2 homeobox #transcriptionfactor #NKX2_3 was highly enriched. DNA binding motif analysis revealed NKX2-3 binding sites in ~40% of the signature genes in #pancreas ECs identified, including PLVAP, suggesting an important regulatory role. 6/

🌲 #Forests🌲 🆕Feature Paper Article Series🌈. "#Physiology of Plant Responses to #WaterStress and Related Genes: A Review", written by Jiaojiao Wu et al. More details 🔗 📗 #droughtstress #plantmorphology #physiologyandbiochemistry #transcriptionfactor

#Transcriptionfactor egr3 transduces biomechanical forces into molecular signals regulating #heart valve development #zebrafish. Image & research by Agatha Ribeiro da Silva et al @TJ_ThomasJuan @StainierLab @mpi_hlr in @ScienceAdvances. Links & archive on

Rapid Formation of Vascular Organoids from #iPSCs via TF Activation. A dual #transcriptionfactor activation method enables rapid generation of #vascularorganoids, accelerating modeling and therapy development.@MeleroMartinLab @BostonChildrens @harvardmed.

Join us for the next Coffee break with TRANSFAC that will be held on May 25th at 5 PM CEST Get the link here #bioinformatics #SystemsBiology #webinar #PromoterAnalysis #DNA #TRANSFAC #TFBS #genes #TranscriptionFactor #ModelOrganism #FruitFly #Zebrafish