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Rami Rahal Profile
Rami Rahal

@ratatat79

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330
Following
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306

Former yeast geneticist and recovering drug hunter turned public biotech investor. Proud πŸ‡±πŸ‡§πŸ‡¨πŸ‡¦. Tweets are solely my opinions.

Joined January 2014
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@ratatat79
Rami Rahal
2 months
RT @bradloncar: PD(L)1xVEGF. 𝐇𝐨𝐰 𝐒𝐭 𝐬𝐭𝐚𝐫𝐭𝐞𝐝: It's a fraud. 𝐇𝐨𝐰 𝐒𝐭'𝐬 𝐠𝐨𝐒𝐧𝐠: You can't afford not to own one. The first class of medicine w….
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@ratatat79
Rami Rahal
2 months
What a terrific Monday morning for biotech! A big congrats to our portfolio companies:.$BPMC: Acquired by Sanofi!! This one is extra special (ex BPMer).$TRVI: FIRST ever successful phase 2 for patients with IPF chronic cough!.$VERA : successful phase 3 for patients with IgAN!.
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@ratatat79
Rami Rahal
6 months
RT @DavidSteensma: DOGE @elonmusk approach feels like a surgeon trying to remove a small tumor using a saw instead of a scalpel, without pr….
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@ratatat79
Rami Rahal
7 months
Surreal to be starting #JPM 2025 watching a documentary of Phillip Sharp, Nobel prize winning discoverer of RNA splicing, FOUNDER of the biotech revolution, and my former thesis committee advisor 🀯! #JPM2025
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@ratatat79
Rami Rahal
7 months
RT @raffcolo: MERRY CHRISTMAS everyone!. (not screaming, just all natural amino acids in their L-form πŸ€£πŸ˜…)
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@ratatat79
Rami Rahal
10 months
RT @paulnovosad: What kind of childhood makes a top scientist? Is it enough to have all the right traits (brilliance, grit, etc) or do you….
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@ratatat79
Rami Rahal
11 months
RT @Pontifex: I am saddened by the news coming from #Lebanon about bombings, death, and destruction. May the international community make e….
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@ratatat79
Rami Rahal
11 months
RT @SamuelBHume: Biggest medical discoveries of the week (🧡). 1/10. A new genetic condition, and insights into the gene that causes it: G p….
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@ratatat79
Rami Rahal
11 months
β€œthe notion that the Fed has superpowers has only become stronger over the last two decades. Pushed to explain why interest rates were at historic lows for much of the last decade, the response you often heard was "the Fed did it.”.
@AswathDamodaran
Aswath Damodaran
11 months
On Wednesday (Sept 16), after months of debate, discussion and handwringing, the Fed lowered the Fed Funds rate by half a percent. If the aftermath feels anticlimactic, it is because of the mythology around central banking:
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@ratatat79
Rami Rahal
1 year
RT @Rainmaker1973: Passenger train lines in the USA vs Europe
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@ratatat79
Rami Rahal
1 year
RT @ky_lahucik: The first 10 drug price negotiations under the IRA are here: .
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@ratatat79
Rami Rahal
1 year
RT @Fullcarry: Milestone of sorts. 1-Year inflation swap at lowest level since Dec 2020
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@ratatat79
Rami Rahal
1 year
RT @BertrandBio: The Emily Whitehead of Lupus is a German patient named Uresa. Need a picture with the chalkboard marked "1 year Lupus free….
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@ratatat79
Rami Rahal
1 year
Finally some good news after a tough few months for biotech! M&A #4 for the year πŸ˜….
@adamfeuerstein
Adam Feuerstein ✑️
1 year
$LLY buyinng $MORF $3.2B - oral integrin for inflammatory bowel disease. $57 per share. 78% premium.
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@ratatat79
Rami Rahal
1 year
Best stat test! Lorlatinib > Alectinib (cross trial comp. ) but is its AE profile bad enough to give $NUVL an opportunity? 🧐 #ASCO24.
@PTarantinoMD
Paolo Tarantino
1 year
Truck test βœ… #CROWN #lcsm
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@ratatat79
Rami Rahal
1 year
3000+% YoY increase in PIPE proceeds in 2024 but only 55% above offer price 😬. Slide courtesy of Dan Dubin/Leerink.
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@ratatat79
Rami Rahal
1 year
Geek out on ADC pharmacology ⬇️.
@raffcolo
Raffaele Colombo
1 year
Nonclinical safety and PK for 14 vedotin ADCs:. - Tissue expression of the targeted antigen rarely correlated with dose-limiting toxicity. - Consistency in highest tolerated doses . - Consistency of nonclinical PK. Must read preclinical πŸ“„ @MCT_AACR!!!.
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@ratatat79
Rami Rahal
1 year
My inner geneticist is celebrating πŸŽ‰ the 12:0 YES vote for the FDA #Adcom on #MRD as an AA endpoint in #MultipleMyeloma! Important win for accelerated drug development in #biotech and for #patients . Now we wait for some other tumor types🀞
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@ratatat79
Rami Rahal
1 year
#ADC tumor penetration and distribution is NOT a biology problem it’s a biophysical problem according to Greg Thurber at #AACR24
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@ratatat79
Rami Rahal
1 year
#AACR24 needs a bigger room for #ADCs next year!.
@raffcolo
Raffaele Colombo
1 year
Packed room for #ADCs @AACR #AACR24
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