Explore tweets tagged as #GRABSensors
1/4 A toolkit of new GRAB fluorescent neuropeptide sensors from Li Lab! These sensors can detect neuropeptides at nanomolar concentration with a robust increase in fluorescence. #GRABSensors #Neuropeptide
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Happy to share our extracellular ATP sensor published on Neuron today. GRAB-ATP1.0, which is based on P2Y1 and cpEGFP, enables the detection of extracellular ATP in vitro and in vivo with good sensitivity and spatiotemporal resolution. #GRABSensors #ATP
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Serotonin dynamics in vivo! We now have new green and red serotonin (5-HT) GRAB sensors enabling detection of 5-HT dynamics in different brain regions and conditions, also suitable for dual-color imaging! #GRABSensors #serotonin @5HT_Society
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1/3 #GRABsensors #histamine We developed a pair of genetically encoded fluorescent sensors for measuring histamine (HA) dynamics. These sensors produced robust increases in fluorescence upon HA application with tens to hundreds nanomole affinities and high specificity.
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Our new GRAB-HA enables the detection of #histamine dynamics in vivo during sleep-wake cycles. With different affinities, GRAB-HA sensors could be used in multiple physiological conditions. Check https://t.co/HPc2zlbgvE to get GRAB-HA and other #GRABSensors
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Excited to introduce our optimized green and red fluorescent dopamine (DA) GRAB sensors #GRABSensors #dopamine Great collaboration with Mitsuko Uchida‘s group at Harvard University, Yingjie Zhu’s group at SIAT, John Williams’ group and Marina Wolf’s group at OHSU.
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A new adenosine GRAB sensor from Li lab. Great collaboration with CIBR Minmin Luo lab and ION Min Xu lab. Ado sensor can nicely report in vivo Ado dynamics and reveal its interesting regulation! #GRABSensors
A GRAB sensor reveals activity-dependent non-vesicular somatodendritic adenosine release https://t.co/MRReXTPeQT
#bioRxiv
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1/6 PGE2 is one of the principal bioactive prostaglandins, critical signaling lipids implicated in body homeostais and pathegenic inflammatory response, yet its in vivo dynamics are largely unknown. #GRABsensors #Prostaglandins
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Discover new researches from the Yulong Li Lab at #SfN23 ！！ Join us Tuesday (Nov. 14) and Wednesday (Nov. 15) for insights into our work. #LiLab #Neuroscience #GRABsensors
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We also developed GRAB-ATP1.0 with large fluorescence response (dF/F0 of 500% - 800%), subsecond kinetics, nM affinity and subcellular resolution. ATP1.0 revealed spatially selective ATP releasing events in living mice during systemic inflammation induced by LPS. #GRABSensors
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A new GRAB fluorescent oxytocin (OT) neuropeptide sensor from Li Lab! GRAB-OT1.0 enables tracking the compartmental OT dynamics in selected brain regions during specific episodes of courtship behaviors of male mice. #GRABSensors#Oxytocin
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(2/3) These highly sensitivity tools complement the highly selective nLight probes from Tommaso’s group, opening up new avenues for a comprehensive understanding of neurochemical dynamics. Stay tuned for more updates! #GRABSensors #Norepinephrine #Neuroscience @NeuroCellPress
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Happy to share our oxytocin (OT) sensor published on @NatureBiotech today. GRAB-OT1.0, based on the cpGFP and bovine-derived OTR, enables the detection of OT ex vivo and in vivo with good sensitivity and spatiotemporal resolution. #GRABSensors #Oxytocin
A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments - @PKU1898
https://t.co/MuCHE2EwsW
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Happy to share our endocannabinoid sensor published on @NatureBiotech today. GRAB-eCB2.0, which is based on CB1R and cpEGFP, enables the detection of eCB in vivo with good sensitivity and spatiotemporal resolution. #GRABSensors #endocannabinoid
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo #PKU
https://t.co/Mg9dDjUT3e
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Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine
https://t.co/KBKc2e8Q6D
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Life Science Across the Globe featuring the Center for Life Sciences, with @yulonglilab @PKU1898 discussing #GRABsensors in #neuromodulation and Hongwei Wang @Tsinghua_Uni talking about the Center for Biological Structure. Open to all!! Oct 14 9am ET https://t.co/cDFJ7TZBtD
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Glad to share our serotonin sensor published on @NatureNeuro today. Congrats to @jinxiawan, group members, and all collaborators @jventon, Julius Zhu @UVA, Miao Jing @chinese_brain and Min Xu @ ION. #GRABSensors #serotonin
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(3/3) Check out our bioRxiv manuscript for all the juicy details: https://t.co/txCei5Zuc8. And hey, we're thrilled to share these cutting-edge NE sensors with the research community! 🎁💪 #GRABSensors #norepinephrine
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Thrilled to share our latest collaborative work with the teams of David Julius and Stuart Brierley @Nature
https://t.co/zJaAmgyBIv
#GRABSensors #Serotonin #Enterochromaffin
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