Hannah De Cleene
@hannahdecleene
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PhD student in the Cell Clearance in Health and Disease Lab @Ravi_Research @VIBLifeSciences
Ghent, Belgium
Joined March 2020
Proud to be part of this super cool research by @maschalidi and co-authors, uncovering SLC7a11 as a brake on efferocytosis by DCs and on wound healing. Go check it out in @nature! @kodiravi @Ravi_Research
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Check out part of my PhD work in our @biorxiv_neursci paper: Newly discovered base barrier cells provide compartmentalization of choroid plexus, brain and CSF. @Vdb_lab and many awesome collaborators. https://t.co/6LWNpUDw7U Hope to share the revised version soon!
biorxiv.org
The choroid plexus (ChP) is a highly understudied structure of the central nervous system (CNS). The structure hangs in the brain ventricles, is composed of an epithelial cell layer, which produces...
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Incredibly proud of the most passionate and hard-working, and now also Doctor, @DaanVerhaege! Also excited to switch the breakfast conversations back to actual science and not just thesis layouts and fonts 😅
Officially PhDone! Very grateful for a wonderful experience and training at the @Vdb_lab @InflamResCen. Final months in 🇧🇪 before our big move to the 🇺🇲 to continue my training in the @kipnislab 🥳
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Beyond excited to be granted the @FWOVlaanderen PhD Fundamental Research fellowship for the next four years in the Ravichandran lab @Ravi_Research together with @kodiravi and @maschalidi! Let's celebrate 🥂
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Congratulations to J. Iker Etchegaray (and many co-authors) for detailing an unexpected role for phagocytosis by the RPE in inducing a local insulin source in the eye, how it is distinct from systemic insulin, and its impact on retinal physiology.
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"Is your job always this fun and easy?" Fun? Yes. Easy? Not so much. Had a great time doing basic Giemsa stainings and looking at immune cells with the Ghentian TAJO (talent atelier for youth) kids today!
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Starting to feel like a migratory hDC taking 4 planes to Cairns, but so excited to reach my lymph node together with @maschalidi!! #DC2022
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“Releasing the 'healing brake' leads to faster recovery from skin wounds in diabetic mice” - @maschalidi @InflamResCen 🩸 The @kodiravi lab discovered a way to accelerate diabetic wound healing which could be a potential strategy for better wound care 👉 https://t.co/rGc8JD8jWr
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https://t.co/FOSWLlchwr Check out our recent review on drugging the efferocytosis machinery: from Tuberculosis to Aging! @Ravi_Research @InflamResCen
nature.com
Nature Reviews Drug Discovery - Aberrations in efferocytosis are associated with numerous inflammatory pathologies, including atherosclerosis, cancer and infections. Here, Mehrotra and Ravichandran...
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Nature research paper: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes
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Thrilled to share our work on identifying Slc7a11 as a brake for efferocytosis by dendritic cells and the relevance to diabetic skin wound healing. Out today in @Nature Huge thanks to all collaborators!@Ravi_Research
https://t.co/E7t4ejqEAC
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