Excited to share our new hPSC-cortical organoid model as preprint. The result of a beautiful collaboration in @studerl lab. Major shout out to @BaggioliniA, now group leader https://t.co/TP02vMuZ5d, Ryan Walsh,@Gabriele_Ciceri,@Rittenhouse_CA https://t.co/8N8vSE4nAM More Info👇

In vivo gut motility controlled by grafted human PSC-derived ENS in severe mouse model of Hirschsprung’s disease. Study now published @CellStemCell on sacral-derived ENS precursors https://t.co/lyRRzCIvl3. Huge effort by Yujie Fan and an amazing team of collaborators @MSK_CSCB

Happy to welcome @lisapavinato in our lab 🎉🎉🎉 Lisa has won the prestigious EMBO award, which started a collaboration between the Brusco lab in Turin and my lab in Switzerland. Very excited about the work that we will be doing together🤩💪💪💪

Remarkably, we also show that extrinsic LIF is required as this ligand is normally produced by non-neural cell types such as brain vascular pericytes, and that integrating hPSC-derived cranial pericytes in cortical organoids can substitute for LIF treatment. Check it out 🙌

This protocol, based on treatment with leukemia inhibitor factor (LIF), dramatically enhances the development of a structured outer subventricular zone germinal layer and outer radial glia progenitor/neural stem cells, two key features of the developing human cortex.

“Generation of human cerebral #organoids with a structured outer subventricular zone” Great work by @BaggioliniA @studerl @giacomelli_eli @gabriele_ciceri Ryan Walsh, Chelsea Rittenhouse & colleagues 🧠🧬 https://t.co/nlK9zXtIDJ

First in person seminar after the long haul of the pandemic, and it could not have been a better venue and audience! Thanks Davide Cacchiarelli for the invitation and @Tigem_Telethon for the first in class hospitality

Don't miss this amazing opportunity in Southern Switzerland! The Baggiolini Lab is opening and looking for PhD students and a Lab technician/Lab assistant!

The Baggiolini lab is opening its doors in September 2022 at Institute of Oncology Research (IOR @IOR_Bellinzona, affiliated to USI @USI_univeristy and member of Bios+).

Now @CellStemCell: Researchers evaluate the modeling of neurodegenerative diseases using #iPSCs. They highlight challenges to exploiting iPSC technology's full potential in neurodegenerative diseases. @giacomelli_eli @BVahsen @studerl https://t.co/6NIQn98dOZ

Very happy to share our review on ALS and iPSC models of neurodegeneration in @CellStemCell in collaboration with amazing co-author @giacomelli_eli and other great colleagues from the @studerl lab and the Talbot lab.

As a result of a beautiful collaboration between the @studerl and the Talbot lab, I am pleased to share our review on ALS and iPSC models of neurodegeneration in @CellStemCell. A very special thank you to @BVahsen for his terrific work as co-author! https://t.co/Mr1XEoaiOU

Happy New Year! Our January 2022 issue is live! The cover story uses iPS models to uncover non-coding structural variations in human brain evolution. Plus we have a Review on ALS and iPS models of neurodegeneration, gastrointestinal assembloids, and more! https://t.co/aGkqvAoDP3

Check out this beautiful story from my friend and colleague @BaggioliniA. Terrific collaboration between the @whitefishlab ,@studerl and @sloan_kettering

Oncogenic competence in melanoma. Check out our work today at @ScienceMagazine 👇 This is the fruit of a terrific collaboration between the @whitefishlab & @studerl lab @sloan_kettering

For those interested in the topic - Below the accompanying perspective in the same @ScienceMagazine issue by Vredevoogd & Pepper. Enabling oncogenes

Why Are Only Some Cells ‘Competent’ to Form Cancer? MSK Scientists Say Context Is Key

Our work on cardiac microtissues and multiwell MEAs to study the electrical phenotype of long QT syndrome is out! Thanks to the amazing team @Luca_Sala, Dorien Ward-van Oostwaard, and @MilenaBellin Check it out! https://t.co/QuPXRriUrS

Thanks to all the amazing collaborators that supported our work: Mathias Treier, @studerl, @KonradBasler, Mitchell Levesque, Reinhard Dummer, @LabSantoro, @ClaudioCantu81. In particular to Mattias Pernebrink from the @ClaudioCantu81 lab

Check out our newest paper on Sall4 and the epigenetic regulation of melanoma cell invasiveness @NatureComms from the Sommer lab @UZH_Science. Major shout out to Johanna Diener.