Gautier Marcq
@gautiermarcq
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MD MSc, PhD Candidate, Onco-Urology Assistant Professor @univ_lille
Joined May 2016
RT @urotoday: Study finds whole pelvis radiotherapy superior to bladder-only in #MIBC treatment. @gautiermarcq @univ_lille joins @l_ballas….
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RT @tompowles1: Big news👋. A positive R3 trial for PD-1 in NMIBC! The CREST trial evaluated sasanlimab (PD-1i)+BCG vs Standard BCG (induct….
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Only 25 % of our 🇫🇷 residents are interested in #Academics. Fantastic talk from @denis_seguier. Nothing more rewarding to see your #trainees shinning on the stage. #BAU2024 @AFUrologie
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Deeply honored to join the #IBCG. Earger to start working with such an esteemed group of colleagues 👩🏫👨🏫 committed to improving #urothelialcancer care. Our patients deserved it. @IBCG_BladderCA @CHU_Lille @univ_lille @WorldBladderCan @CancerVessie @WesKassouf
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RT @urotoday: #LEGEND trial investigates EG-70 in #BladderCancer patients. 💡 Exciting insights from @gautiermarcq @univ_lille and @zklaasse….
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RT @tompowles1: Just out. Ipi/nivo didn’t hit OS in cisplatin ineligible or PD-L1 +ve in 1st line UC in CM901. Surprising? Durva/treme (als….
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6/6. Michael Kim, Ionut Busca, Hamidreza Abdi, Mark Dawidek, Michael Uy, Gagan Fervaha, @Nimira_A, Jonathan Izawa, Claudio Jeldres, Ricardo Rendon, @BobbyShayegan.
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5/6.Our results advocate for PLNI when treating #MIBC with ☢️ ! .More RCT are needed as an expression of editorial concern was published regarding the only available RCT on the topic
pubmed.ncbi.nlm.nih.gov
Expression of Editorial Concern: Tunio MA, Hashmi A, Qayyum A, et al. Whole-pelvis or bladder-only chemoradiation for lymph node-negative invasive bladder cancer: Single-institution experience. Int J...
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4/6.📋 Our results showed that PLNI was associated with:.✅ Improved CSS (HR= 0.66 [95% CI, 0.47 to 0.93]; P = .016) .✅ Improved OS (HR, 0.68 [95% CI, 0.54 to 0.87]; P = .002).
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3/6.In order to answer our ❓and compare outcomes: we used a statistical 🤓 method to balance covariates: IPTW (Inverse Probability Treatment Weighted Analysis). In the weighted cohort: ✅All baseline covariates were well balanced ! (All ASD < 0.1).
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2/6.- From a 🇨🇦🇨🇦 database (10 👨🏻🎓👩🏻🎓 centers), we identified 809 patients treated with curative intent ☢️.- Out of the 599 included patients: 230 received Bladder only (BO) and 369 Bladder + PLNI (whole-pelvis, WP). - WP-RT patients had more ⚠️ risk (cN+, LVI).
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1/6 .- From ⚔️Surgical cohorts: rate of lymph node invasion can be seen in up to 20%-30% .BUT Pelvic lymph node ☢️ irradiation (PLNI) is under debate ⁉️. - Our ❓: As ☢️ may be offered to ⬆️⬆️ risk #MIBC (higher cT, hydronephrosis, cN+, CIS + and LVI +), PLNI is more pertinent?.
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Just in 👉 @JCO_ASCO Benefit of Whole-Pelvis Radiation ☢️ for Patients With #MIBC . . 👇👇👇TWEETORIAL 👇👇👇.
ascopubs.org
PURPOSEThe value of pelvic lymph node irradiation is debated for patients with muscle-invasive bladder cancer (MIBC) undergoing curative-intent radiation therapy (RT). We sought to compare the...
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RT @NEJM: In patients with muscle-invasive bladder cancer, extended lymphadenectomy did not improve disease-free or overall survival as com….
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RT @SWilliams_MD: @JFontugne presenting at #IBCN24 @IBCN1997 AI subtype prediction model in bladder cancer. AI value added tools to general….
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RT @zklaassen_md: Benefit of WP-RT for MIBC: 🇨🇦IPTW Analysis @urotoday #IBCN2024 @IBCN1997 @gautiermarcq . 🇨🇭n=599, 369 WP-RT vs 220 BO-RT….
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RT @WesKassouf: Excellent opportunity for a medical oncologist @mcgillu @cusm_muhc to join a collaborative and enriched academic environmen….
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RT @SWilliams_MD: @liaojoe1 presenting at #IBCN24 @IBCN1997 in Bern 🇨🇭 augmented cystoscopy AI. Phenomenal value added technology so key to….
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RT @PBlanchardMD: Interesting efficacy signal for bladder preservation (TMT) + nivolumab. Increased #bladdercancer free survival & OS va….
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