Felix Marsh-Wakefield
@doc_merlin
Followers
148
Following
807
Media
4
Statuses
34
Immunology PhD by day, musician by night.
Australia
Joined April 2019
Excited to co-chair the 2024 Cancer & Immunology Ideas Forum with @DrHelenMcGuire, @doc_merlin and @sarah_sasson! Join us for groundbreaking discussions at the intersection of #Cancer Res & #immunology. @CancerSPHERE, @SydCancerPtnrs @UNSWMedicine @nanostringtech @BDBiosciences
📣 We're Back! The 4th Cancer & Immunology Ideas Forum is on: 🗓️ Friday 16th August 2024 📍NSW Teachers Federation Conference Centre, Sydney 💸 Cost = free! This year @UNSW and @Sydney_Uni are cohosts 🤝 Check out the program and reserve your spot here: https://t.co/7HzAsVpzUW
0
5
19
Very pleased to announce that our paper, "SuperCellCyto: enabling efficient analysis of large scale cytometry datasets" has just been published in Genome Biology!! Paper: https://t.co/eCxO9284Yk Code: https://t.co/1PlmXGKWmP 🧵👇
github.com
SuperCell for Cytometry data. Contribute to phipsonlab/SuperCellCyto development by creating an account on GitHub.
4
10
38
0
0
1
Our preprint is out, using #IMC on #HCC tumours. We identified a unique neighbourhood within tumours consisting of VEGF+ perivascular macrophages and immune cells that could play a key role in angiogenesis and vascular permeability @angeferg @palendira C Santhakumar G McCaughan
Spatial mapping of the hepatocellular carcinoma landscape identifies unique intratumoural perivascular-immune neighbourhoods https://t.co/ugWWj17T22
#medRxiv
1
3
18
The first paper from my lab, driven by an awesome postdoc @EV_wombat, and inspired by the 2022 @ozsinglecells/ASI hackathon!
SuperCellCyto: enabling efficient analysis of large scale cytometry datasets https://t.co/CezXuLMzGB
#bioRxiv
8
17
59
0
1
4
What a team! 🤩 Great talks, discussions and fun at #CYTO2023 in @Montreal So happy to finally meet in person with so many great colleagues @doc_merlin @TomAsh_1 @DrHelenMcGuire @Lauretalila Avrill Aspland 🤩 and many others. 🥰to see the @CIML_Immunology well represented
0
4
41
📢 Epic battle of nature vs nurture!! 🔥Come along April 27th to *FREE Public Lecture* on all things immunology 🤩environmental influence! Check out amazing line up of experts 👇👇, hosted @Sydney_Uni with support from @ASImmunology more info & rego https://t.co/28zHug5trz
0
11
17
More work with Georges Grau and Linda Lin investigating #monocyte transmigration in #multiplesclerosis after #cladribine treatment https://t.co/RRYT6FDSU0
@IJMS_MDPI intermediate monocytes from cladribine-treated MS patients were impaired crossing a BBB @CentenaryInst @Sydney_Uni
mdpi.com
Multiple sclerosis (MS) is a disease in which the immune system damages components of the central nervous system (CNS), leading to the destruction of myelin and the formation of demyelinating...
0
0
5
More great work from Florentina Aglas-Leitner and Georges Grau using #masscytometry in #multiplesclerosis after #alemtuzumab looking at #innatelymphoidcells in @ClinTransImmuno
https://t.co/LLepAlMLP0 CD56bright #NKcells increased in MS and shifts between ILC1, ILC2 and CCR6+ILC
onlinelibrary.wiley.com
In this study, we found CD56bright natural killer (NK) cells increased in relapsing multiple sclerosis (MS) patients. MS patients further demonstrated proportional shifts in type 1 innate lymphoid...
0
5
7
Special thanks to Simon Hawke, Pierre Juillard, Annette Juillard @photoimmunology @SydneyCytometry
0
0
0
Excited to share work with Florentina Aglas-Leitner and Georges Grau looking at #ILC in #multiplesclerosis patients with #cladribine in @SciReports. Cladribine depleted select subsets whilst immature ILC were higher https://t.co/4TCPFIDWOd
@CentenaryInst @Sydney_Uni
1
0
4
Proud of students work with Georges Grau @JCM_MDPI #multiplesclerosis issue. Rachel Ford & Kristy Nguyen found CD4+ TEM & CD8+ TCM had impaired transmigration across BBB in two MS cohorts after #cladribine
https://t.co/SzRzxQ6h36 or #alemtuzumab
mdpi.com
The breakdown of the blood–brain barrier (BBB) and the trans-endothelial migration of lymphocytes are central events in the development of multiple sclerosis (MS). Autoreactive T cells are major...
0
0
6
A fairy tale paper with @Dr_KaziNahar looking forward to what comes next!
Out now @JCI_insight our work on immunotherapy-induced colitis. A great collaborative work with @MelanomaAus @amenzies9 @ProfGLongMIA @ProfRScolyerMIA @inespiresilva @JWilmott38 study led by @Dr_KaziNahar and supported by @doc_merlin
0
0
4
This week we ran our first @ASImmunology systems immunology hackathon to tackle emerging challenges in #singlecell #multiomics & #cytometry analysis, supported by @ChanZuckerberg @GriffithUniVC & @ozsinglecells. Astounded by what this group achieved in just 2 days - stay tuned!
1
12
42
Thanks for the help team! @TomAsh_1 @dianashinko @Givanna90 @mnread @DrHelenMcGuire @photoimmunology @SydneyCytometry 👨💻👨🔬🔬⚗️
B cells play a major role in #MultipleSclerosis, with many successful therapies removing them from circulation. Featured this month, @doc_merlin et al @Sydney_Uni @CentenaryInst find peripheral B cell dysregulation associated with MS relapse. #ICBnews
https://t.co/3BwK9PLuvq
0
1
4
We have started some exciting work with Prof Geoff McCaughan on Human Hepatocellular Carcinoma. As a prelude the team has looked at the available approaches to spatially resolving these tumours in this review article. Great work @doc_merlin @angeferg
journals.sagepub.com
Hepatocellular carcinoma (HCC) is a common and deadly cancer worldwide. Many factors contribute to mortality and place an individual at high risk of developing ...
1
2
15
Immensely proud to see @Givanna90's novel time-series #singlecell #cytometry clustering tool '#TrackSOM' online with Cytometry A. This was a wonderful multidisciplinary collaboration across @Sydney_Uni including @mnread @nickjck @doc_merlin and others. https://t.co/D7ZpwfCzLy
2
11
28
Merry Xmas! This is a picture of liver by IMC. Don't ask what markers they are, I picked them because they're pretty #imaging #masscytometry #pretty #Christmas @SydneyCytometry @angeferg @palendira
1
2
12
Featured this month is a review from @doc_merlin et al on the use of high‐dimensional cytometry in #immunology research. Data from these experiments are often under‐utilised. Are you making the most of YOUR data? @TomAsh_1 @DrHelenMcGuire #BigData #ICBnews
0
8
23