Felix Marsh-Wakefield
@doc_merlin
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Immunology PhD by day, musician by night.
Australia
Joined April 2019
RT @VittorioOrazio: Excited to co-chair the 2024 Cancer & Immunology Ideas Forum with @DrHelenMcGuire, @doc_merlin and @sarah_sasson! Join….
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RT @givanna90: Very pleased to announce that our paper, ."SuperCellCyto: enabling efficient analysis of large scale cytometry datasets".has….
github.com
SuperCell for Cytometry data. Contribute to phipsonlab/SuperCellCyto development by creating an account on GitHub.
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Blazing-fast image creation – using just your voice. Try Grok Imagine.
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Our preprint is out, using #IMC on #HCC tumours. We identified a unique neighbourhood within tumours consisting of VEGF+ perivascular macrophages and immune cells that could play a key role in angiogenesis and vascular permeability @angeferg @palendira C Santhakumar G McCaughan
Spatial mapping of the hepatocellular carcinoma landscape identifies unique intratumoural perivascular-immune neighbourhoods #medRxiv.
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RT @BelindaPhipson: The first paper from my lab, driven by an awesome postdoc @EV_wombat, and inspired by the 2022 @ozsinglecells/ASI hacka….
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RT @RafaJArguello: What a team! . 🤩 Great talks, discussions and fun at #CYTO2023 in @Montreal . So happy to finally meet in person with so….
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RT @DrHelenMcGuire: 📢 Epic battle of nature vs nurture!! 🔥Come along April 27th to *FREE Public Lecture* on all things immunology 🤩environm….
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More work with Georges Grau and Linda Lin investigating #monocyte transmigration in #multiplesclerosis after #cladribine treatment @IJMS_MDPI intermediate monocytes from cladribine-treated MS patients were impaired crossing a BBB @CentenaryInst @Sydney_Uni.
mdpi.com
Multiple sclerosis (MS) is a disease in which the immune system damages components of the central nervous system (CNS), leading to the destruction of myelin and the formation of demyelinating...
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More great work from Florentina Aglas-Leitner and Georges Grau using #masscytometry in #multiplesclerosis after #alemtuzumab looking at #innatelymphoidcells in @ClinTransImmuno CD56bright #NKcells increased in MS and shifts between ILC1, ILC2 and CCR6+ILC.
onlinelibrary.wiley.com
In this study, we found CD56bright natural killer (NK) cells increased in relapsing multiple sclerosis (MS) patients. MS patients further demonstrated proportional shifts in type 1 innate lymphoid...
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Special thanks to Simon Hawke, Pierre Juillard, Annette Juillard @photoimmunology @SydneyCytometry.
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Excited to share work with Florentina Aglas-Leitner and Georges Grau looking at #ILC in #multiplesclerosis patients with #cladribine in @SciReports. Cladribine depleted select subsets whilst immature ILC were higher @CentenaryInst @Sydney_Uni.
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Proud of students work with Georges Grau @JCM_MDPI #multiplesclerosis issue. Rachel Ford & Kristy Nguyen found CD4+ TEM & CD8+ TCM had impaired transmigration across BBB in two MS cohorts after #cladribine or #alemtuzumab
mdpi.com
The breakdown of the blood–brain barrier (BBB) and the trans-endothelial migration of lymphocytes are central events in the development of multiple sclerosis (MS). Autoreactive T cells are major...
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A fairy tale paper with @Dr_KaziNahar looking forward to what comes next!.
Out now @JCI_insight our work on immunotherapy-induced colitis. A great collaborative work with @MelanomaAus @amenzies9 @ProfGLongMIA @ProfRScolyerMIA @inespiresilva @JWilmott38 study led by @Dr_KaziNahar and supported by @doc_merlin
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RT @TomAsh_1: This week we ran our first @ASImmunology systems immunology hackathon to tackle emerging challenges in #singlecell #multiomic….
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Thanks for the help team! @TomAsh_1 @dianashinko @Givanna90 @mnread @DrHelenMcGuire @photoimmunology @SydneyCytometry 👨💻👨🔬🔬⚗️.
B cells play a major role in #MultipleSclerosis, with many successful therapies removing them from circulation. Featured this month, @doc_merlin et al @Sydney_Uni @CentenaryInst find peripheral B cell dysregulation associated with MS relapse. #ICBnews.
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RT @palendira: We have started some exciting work with Prof Geoff McCaughan on Human Hepatocellular Carcinoma. As a prelude the team has lo….
journals.sagepub.com
Hepatocellular carcinoma (HCC) is a common and deadly cancer worldwide. Many factors contribute to mortality and place an individual at high risk of developing ...
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RT @TomAsh_1: Immensely proud to see @Givanna90's novel time-series #singlecell #cytometry clustering tool '#TrackSOM' online with Cytometr….
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Merry Xmas! This is a picture of liver by IMC. Don't ask what markers they are, I picked them because they're pretty #imaging #masscytometry #pretty #Christmas @SydneyCytometry @angeferg @palendira
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RT @ImmunolCellBiol: Featured this month is a review from @doc_merlin et al on the use of high‐dimensional cytometry in #immunology researc….
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