Davi Bock
@dddavi
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network anatomist also dddavi at bluesky
University of Vermont
Joined January 2010
Hard to overstate how pleased I am that the #flywire consortium converted our FAFB ("Full Adult Fly Brain") EM volume into a connectome, and that the resulting science has been (and will be) so impactful. Thanks to everyone involved.
Here it is! A huge milestone in neuroscience – the complete connectome of the fly brain from the FlyWire team (@FlyWireNews). In this special issue, we have 9 research articles. I’ll try to summarize them in a couple threads starting here 🧵
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This to me signals a serious escalation on the assault on free speech.
usermag.co
"They straight up tried to get something out of me that I think they could use to basically detain me permanently"
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"The future is an infinite succession of presents, and to live now as we think human beings should live, in defiance of all that is bad around us, is itself a marvelous victory." 4/4 Howard Zinn, "The Optimism of Uncertainty" (2004)
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Final week to register for the Crete meeting - judging from the people who already signed up, this is shaping up to be a super exciting week for Drosophila circuits enthusiasts.
Fellow Fly Folks - registration for the Crete Fly Circuits meeting just opened! This will be a fun and exciting conference for everyone working on neural circuits & behavior in Drosophila 🪰. June 15 - 21/2025. And yes, the venue is right by the sea 🌊. https://t.co/o9ottpowrz
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The BRAIN Initiative has driven unprecedented progress in neuroscience, but a 40% funding cut threatens this momentum. Restoring funding would help solve more mysteries of the brain and developing life-changing treatments. #studyBRAIN
nature.com
Nature Neuroscience - Launched in 2013, the BRAIN Initiative (BRAIN) in the United States aimed to unlock the mysteries of the brain and develop new treatments for neurological and neuropsychiatric...
The BRAIN Initiative has been an engine of innovation but is now fighting for its survival. Here we discuss why BRAIN is special and why we must all fight for it now https://t.co/1SECiT2G7m
@TheHongLab @DrZoePhD @bjmarlin @doristsao @moriel_z @HongkuiZeng XiaokeChen ZivWilliams
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This is a really heroic experiment recording associative learning neurons in the fly brain over two hours while two flies interact with one another. This device and this approach can generally enable many more kinds of social interaction experiments
We recorded the activity of neurons within this network during 2 hours of social interactions. Interestingly, as the animals became more sociable the baseline and locomotor-related activity greatly diminished in MBONs previously implicated in aversive learning.
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Whole-brain spatial organization of hippocampal single-neuron projectomes
science.org
Single-cell projectome analysis elucidates axonal arborization of more than 10,000 neurons in the mouse hippocampus.
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The $3B Human Genome Project was started under a Republican administration and later acknowledged by the Obama admin to have returned $141 to the economy for every $1 spent. Science has a higher ROI than any other category of government spending.
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Thanks @dddavi for taking a pic the moment I first saw our cover of @Nature! A magical time to be at @SfNtweets #sfn 2024. To the future!
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📣NEURO FACULTY JOBS! 🧠 University of Oxford opened *2* positions for Associate Professors of Neuroscience! Come be our colleague! Applications due: noon, 18 Nov 2024 More info: https://t.co/DYMhhz6COJ
@UniofOxford @OxfordDPAG @OxNeuro @PembrokeOxford @hilda_beastoxf
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I've combined some of these together into a new #neuro #visualization "In the eye of a fly": Using the @FlyWireNews visual system wiring diagram, #Brian2 spiking #neuron simulator, and #blender. Information flow through the chiasms, across a topographic map.
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My first-author paper is out today @NatureComms ! We investigated how oligodendrocytes produce myelin. Using volume EM, we characterized oligodendroglial ER (magenta) in developing myelin and explored nonvesicular lipid transport involved. #lipidtime
https://t.co/COW6ZjIQk7 (1/n)
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For Reasons it just came to mind that retina great @whatishealth21 Peter Sterling (computer-based volume EM circuit reconstruction in 1984!) was also a Freedom Rider. https://t.co/snfB1KP6li...
https://t.co/Dq6f3gGfXG...
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Protists are awesome! Neat to see the biochemical & structural mechanisms for rapid cell shape change start to get worked out. :)
What. The. Fuck?!? 🤯🤯
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Interested in working on a state-of-the-art connectomics pipeline at its birthplace as a postdoc? We’d love to hear from you! :) https://t.co/RkhoxzuJqE
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strong reuse of open FlyWire and FAFB image & manual tracing data in this interesting-looking segmentation effort: https://t.co/anUIW7vVZu Idea seems to be to embed features from small pre-segmented fragments and train them to hook up correctly using FlyWire & FAFB ground truth
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Fellow Fly Folks - registration for the Crete Fly Circuits meeting just opened! This will be a fun and exciting conference for everyone working on neural circuits & behavior in Drosophila 🪰. June 15 - 21/2025. And yes, the venue is right by the sea 🌊. https://t.co/o9ottpowrz
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working day and night on a proposal and searching for something else ran into this nice interview between my graduate advisor Clay Reid @rclayreid and fellow labmate at the time Prakash Kara @Prakash3Photon :
spiedigitallibrary.org
Neurophotonics Associate Editor Prakash Kara (Univ. of Minnesota) interviewed his colleague Clay Reid (Allen Institute for Brain Science) about his pioneering work in neuroscience.
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