David Breen
@breenneurology
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Neurologist. Movement disorders specialist. Researcher. Dad of three. @AnneRowlClinic @EdinUniBrainSci @EdinUniUsher
Edinburgh, Scotland
Joined February 2017
I wasn’t aware this was happening No change to DVLA driving rules for functional seizures but motor FND now specifically listed for first time as something patients need to notify Another reason to be careful in diagnosing “FND” in those with mild functional symptoms
🚦 New Driving Rules You NEED to Know in 2025! 🚗 The UK’s Medical Fitness to Drive guidelines have changed. 👉 Functional Neurological Disorder (FND) is now included. 👉 Standards for dissociative seizures updated. 👉 Mandatory DVLA notification required. In dissociative
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⭐ Are you a visionary researcher with an interest in Parkinson’s?⭐ We are recruiting for 4️⃣ outstanding Group Leaders to join our new Parkinson’s Research Centre in partnership with @ParkinsonsUK 🙌 Apply here by 22 September👉 https://t.co/U3RM71oWFh
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Great meeting at the Crick today. @EJS_ACT_PD promises to be a game-changing trial platform. Grateful for the meaningful support to deliver the study in Scottish sites. @NRS_NDN @AnneRowlClinic @EdinburghParki2 @ParkinsonsUKSco @GordonWDuncan
Very excited to be at the @EJS_ACT_PD annual meeting today - an extremely ambitious & exciting new multi-arm, multi-stage clinical trial platform for testing potentially disease modifying therapies for #Parkinsons - @CureParkinsonsT is proud to be one of the funders involved
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The first ever treatment for Friedreich’s #ataxia – for which @UCLIoN and @UCLH led the UK trial – has been approved for use in the UK by the medicines’ regulator. https://t.co/tPc5ucZSVY
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A wonderful few days in Amman, Jordan at the 19th International Conference of the Jordan Medical Society at the invitation of Prof Ghnaimat. With @AAlMohammad87 @AOlssonBrown @breenneurology and others @RCPEdin Welcome and hospitality, as always, exemplary.
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Gillian is a great PD Nurse Specialist in Fife. Help her if you can. @EdinburghParki2 @ParkinsonsUKSco
justgiving.com
Help Gillian Aldrich raise money to support Parkinson’s UK
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Positivity and resilience in abundance last night. Great to see the varied, locally-delivered activities helping people live well with Parkinson’s. Well done everyone! @EdinburghParki2 @HastingsGavin @AnneRowlClinic @GordonWDuncan @HelenMatthewsQ
Tonight we took over @ScotParl! We packed out the place to showcase some of the ways people get active, get creative to live well with #Parkinsons🧵
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Disappointing but extremely important results for Parkinson’s. Exenatide once a week versus placebo as a potential disease-modifying ...
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Thanks for highlighting our work @MichaelOkun! We’re currently planning study using population-level routinely collected high street fundus images from optometrists to study various prodromal retinal PD markers. @SCONeResearch @MacGillivrayLab @EdinUniNeuro @AnneRowlClinic
Does Parkinson's affect the eyes? YEP. Does the optic disc fade in Parkinson's? Apparently YES according to Samuel Gibbon and colleagues in a brand new article @MDJ_Journal. Key Points: - The authors remind us that retinal changes measured w/ a technique called optical coherence
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Our PhD student Nina is raising money for the local PUK Edinburgh Branch by walking 100km of the Jurassic Coast in 2 days. Support her if you can. https://t.co/VAdgk1BGWv
@EdinburghParki2 @ParkinsonsUKSco @lcanresearch @PrecisionMedPhD
justgiving.com
Help Nina Diviza raise money to support Parkinson’s UK
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New publication from @covidcns - highlights that patients with neurological or psychiatric complications of COVID-19 had worse long term functions outcomes which impacted their activity of daily living (ADL), employment & mental health. Read more... https://t.co/C7JWPmJOa7
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Clearly, there have been many updates in the field of Mild Cognitive Impairment (#PD-MCI) and Dementia (#PDD) since the #MDS Guidelines were published for #Parkinson disease. Here we call for a Task Force to update these criteria to benefit our patients https://t.co/tlci9idlGY
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New paper from Ju and @PDandHDLab which validates a simple prognostic model for early PD.
movementdisorders.onlinelibrary.wiley.com
Background A simple prognostic model was previously developed to predict the probability of recently-diagnosed patients reaching negative outcomes (postural instability, dementia or death) in a...
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#Covid cognitive deficits even 12-18months AFTER hospitalisation associated with reduced #brain volume on MRI and #brain-injury biomarkers in blood. OUT TODAY in @NatureMedicine
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Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial - The Lancet Neurology
thelancet.com
Neither memantine nor trazodone improved efficacy outcomes compared with placebo. This result is sufficiently powered to warrant no further testing of trazodone or memantine in motor neuron disease...
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Good luck to the team who are cycling from Edinburgh to Iona next month to raise money for @CureParkinsonsT. Support them if you can.
justgiving.com
The Celtic Challenge is an epic four day cycling adventure that involves riding 200 miles from Edinburgh to the beautiful Isle of Iona. Please help our team of cyclists raise crucial funds for...
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Meet #npjParkinsons new Deputy Editor for clinical research, Dr David Breen @breenneurology! Learn more about Dr Breen and his research in our Q&A at https://t.co/bRmeaiLvkk
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Congrats to @Iben_Lundgaard for putting on really successful Glymphatic Symposium last week in Lund. Fascinating new(ish) area of research into waste clearance system in the brain. @zanna_voysey
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The Physio4FMD trial has been published in @LancetNeuro today. This study is the culmination of over 10 years of work from many collaborators. In this thread I will summarise this work and our findings. @jonstoneneuro @MarstonLouise @rachmareehunter
https://t.co/MVEBw6qvoi
thelancet.com
Although more participants who were assigned specialist physiotherapy self-rated their motor symptoms as improved and had better scores on subjective measures of mental health, the intervention did...
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Apart from the fact I was losing my voice (!), I enjoyed the chat with Julie and Helga.
New NoSPRIG podcast keeping you in touch with the latest #Parkinsons research. Listen on your usual podcast platform or at https://t.co/DKnABIaCm8, where our whole back catalogue is available to browse through. Endless hours of information!
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