Amino acid supplementation enhances the uptake of lipid nanoparticles carrying #mRNA therapies in vitro and in mice, suggesting this simple approach could overcome delivery efficacy roadblocks in mRNA #GeneTherapy. @biohub @ShanaOKelley @KelleyLabs https://t.co/yLZGgzfm6P

Amino Acid Cocktail Supercharges LNP Delivery for mRNA and CRISPR Therapies Co‑injecting three common #aminoacids with LNPs dramatically boosted both mRNA delivery and CRISPR #geneediting efficiency in preclinical models @biohub #LNP #mRNA #CRISPR https://t.co/sFhoPehA3C

Studies of uterus transplant recipients reveal how immune cells shape pregnancy outcomes, an amino acid cocktail enhances nanoparticle delivery of therapeutic mRNAs in mice, and more this week in #ScienceTranslationalMedicine. https://t.co/zbEAufOzk7

The Biohub team found that adding just 3 amino acids (methionine, arginine & serine) to LNP (liquid nanoparticle) injections boosts mRNA delivery up to 20x and pushes CRISPR editing efficiency to ~90% in a single dose. 🧬 Read the paper ⬇️

What if the key to better mRNA therapies wasn't redesigning the delivery vehicle—but feeding the cell? A new study in @ScienceTM from @DanielWang_SC & @ShanaOKelley describes a surprising solution to a stubborn problem. Read more ➡️ https://t.co/Xr5L4mmZO1

Location—it matters in real estate and, researchers are finding, in immunity. A new study in @NatImmunol from @RohamParsa & Daniel Mucida of @RockefellerUniv tracks the T cell response across organs, with implications for improving immune-manipulating therapies. Read more ▶️

A new tool from Rockefeller's Daniel Mucida and @biohub in @NatImmunol allows scientists to closely follow newly activated T cells as they travel and change during an infection—it may inform future therapies for infection, cancer, and autoimmunity. 🔗: https://t.co/dxpkcaGN5B

I hope you can join us for this webinar! This Thursday, I'll present on the Molecular Pixelation of CAR T cells. We measured cell surface protein topologies for over 8,000 single cells that capture new phenotypic information for CAR T cell exhaustion.

🩷💚💙💜 We stand in solidarity with the rare disease community worldwide. On #RareDiseaseDay, we light up our offices to honor patients, families, clinicians, and researchers advancing understanding and care.

It was an inspiring day of science, building community and sharing advances in AI-powered imaging and computational biology at our AI Applications in Biology Symposium! Grateful to our keynotes: @NHatzakis, Martin Steinegger, Xinyi Zhang.

Clemons notes that “we should follow evolution’s lead and develop therapeutics that target MurJ. This demonstrates the power of basic biology to help us solve problems in medicine." Read more from @Caltech ⤵️ https://t.co/AAoJzOwUfZ

All 3 phages produce small proteins that jam up MurJ, which is essential for building the cell wall. No wall, no survival. Using cryo-EM, Bil Clemons, Biohub Scientist in Residence, and his team at @Caltech captured atomic-level images of these interactions.

Antibiotic resistance is a public health crisis. But viruses called phages have been solving this problem for millennia. New research in @Nature reveals how 3 different phages attack the same weak spot—a protein called MurJt—potentially leading to a new class of antibiotics.🧵

Crispr’s ability to cut genetic code like scissors has just started to turn into medicines. Now, gene editing pioneer Jennifer Doudna wants to build an entire ecosystem to bring these treatments mainstream. #Forbes250 Learn more: https://t.co/PWaoNvXRcK 📸: Cody Pickens for

The human body is an information system — and AI is helping us decode it to cure or prevent disease. In @bigthink, our scientists and researchers explain how #AI is helping us simulate human cells, visualize hidden pieces of biology, and detect disease before symptoms appear.

New research led by Andrea Califano, Dr, unveils a framework to decode hundreds of thousands of previously “uninterpretable” cancer mutations— helping clinicians prioritize more effective treatments and avoid unnecessary ones. @officialbiohub 🔗 https://t.co/FhZC46S40h

Big congrats to @AashishManglik 👏

And also celebrating @adamdelazerda from the Biohub Investigator Program on the #TIME100 Health List, who has pioneered work in molecular imaging technologies. Check out his work in @TIME ➡️ https://t.co/St2y909tZB

🎉Biohub Investigator @PGeldsetzer1 has been named to the 2026 #TIME100 List of the World’s Most Influential Leaders in Health for his groundbreaking studies showing how a shingles vaccine lowers risks of developing dementia. Read more @TIME ➡️ https://t.co/avamlFd2Zm

AI-powered biology is changing how research happens. On BioTech Nation, Dr. Shana Kelley, our President of Bioengineering & Head of Biohub Chicago, shares how #AI can accelerate discovery and open new paths for understanding biology and disease. 🎧 Listen to the full