Asis Palazon
@asispalazon
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Group leader, Immuno-Oncology Lab at @CICbiogune
Bilbao, Basque Country
Joined February 2018
Our latest research in Cellular and Molecular Life Sciences! We explore how Syndecan-3 (SDC3) influences macrophage behavior within the TME. https://t.co/WYLje8lLI9
#Immunotherapy #CancerResearch #Macrophages #Syndecan3
link.springer.com
Cellular and Molecular Life Sciences - The tumour microenvironment (TME) is a highly structured ecosystem that surrounds a tumour and plays a crucial role in tumorigenesis. As one of the most...
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1/13 In our new @CD_AACR paper we report an improved strategy to apply immunotherapy to brain metastasis, specially to those that are symptomatic, which has been reported to poorly respond to immune checkpoint blockade antibodies.
aacrjournals.org
Genetic and pharmacologic approaches uncover functionally relevant microenvironment heterogeneity to improve the efficacy of immunotherapy in brain metastasis.
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PhD-efeated! 🎉 Happy to announce I defended my thesis on July 11th. Heartfelt thanks to the AP lab, and the committee @SanchoLab, @ArkaitzLab, and @Casanova_Acebes for your invaluable insights. Honored to discuss my work with experts I look up to. 🔬 👤@asispalazon 🏛️@CICBIOGUNE
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👥 Yesterday, we met with @alena_grosvidal (@VHIO), @asispalazon (@CICbioGUNE), and team members at the annual meeting of our @FundlaCaixa project! 🔬 For over 3 years, we've been working on the development of enabling technologies for T-cell immunotherapy of solid tumors 🧬
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Brillant talk by Borja Jiménez Lasheras from @asispalazon @CICbioGUNE at #MWC2024 Harald von Boehmer Midwinter Conference on Neddlytation on CD8 T cells 👏🏔️ very big work and presentation!
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New potential #therapeutic target for #lungcancer treatment 🔬 Researchers from @asispalazon #CICbioGUNE @brta_eus @Ikerbasque @ERC_Research @ContraCancerEs 🧾 The #study is now in @JCI_insight 🎉 Congratulations to all the authors! 🔗 https://t.co/WjlCsbAtNM
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Thrilled to share my research on tumor-reactive T cells at #CICON23. A big thank you to @pezcoller for the travel grant! @CancerResearch @ENCI_network @AACR @C_IMT
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Grateful for attending at #CICON23, sharing some results of my project. @ContraCancerEs @InfoGetica @CancerResearch @ENCI_network @AACR
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El Dr. Asís Palazón investiga en @CICbioGUNE en torno al desarrollo de terapias celulares innovadoras para el tratamiento del cáncer. 🔬 Esta investigación cuenta con el apoyo de @ContraCancerEs y Asociación Contra el Cáncer Bizkaia ✨ https://t.co/Vz5Kj8uHQP
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🛑SAVE THE DATE! 3rd ASEICA ASPIC International Meeting: Cancer Immunology, Tumor Microenvironment and Metastasis 📅October 26th & 27th 2023 🏙️Porto 📘 https://t.co/QZ1O9UOrIZ ✅You may join ASEICA or @ASPICancro before registration and benefit from the discounted rate
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Researchers from @GlycoNMRBilbao @JuneErenoOrbea @asispalazon @CICbioGUNE @Ikerbasque @brta_eus unveiled the #therapeutic potential of 𝐒𝐢𝐠𝐥𝐞𝐜-𝟏𝟓 as a promising #cancer immunotherapy #target 🧾 @NatureComms 🎉 Congratulations to all the authors! 🔗 https://t.co/ftUcKvGA7D
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New (and sweet) partner in town!! In our last work we determined the crystal structure of Siglec-15 checkpoint and identified CD11b as a glycan-dependent binding partner on T cells Read full #glycotime story at @NatureComms here ⬇️⬇️ https://t.co/tn1ylZPcxm
nature.com
Nature Communications - Siglec-15 inhibits T cell function in the tumor microenvironment. Here, the authors solve the crystal structure of antibody-bound Siglec-15, characterize its binding mode to...
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🏃🏽♂️🏃🏽♀️AUPA GIPUZKOAKO FARMAZIALARIAK🏃🏽♂️🏃🏽♀️ 👏🏽Egun ederra atzokoa👏🏽 👏🏽Gran día el de ayer👏🏽 #CarreraEmpresas
#EnpresenLasterketa 🏆ZORIONAK🏆
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📢 Looking for a master student to work on advanced #hydrogels for the delivery of #CAR-T cells in solid #tumors in collaboration with @MariaCaffarel @Biodonostia,@LBasabeDesmonts and @janirenaiz @upvehu and @asispalazon @CICbioGUNE. How to apply? 👉 https://t.co/AHRPqRJzA1
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Lasterketa Solidarioa. Aurten bilduko den diru guztia, @VHIO ko @DrCeSarcoma doktorea buru den Onkologia Institutoko Translazio ikerketa Taldera bideratuko da. #Burdinhesikoelkartasuna #sarkoma
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➡️Next: Session 5 ‘PRECISION IMMUNOTHERAPY’ with: ✅Thomas F. Gajewski (@UCCancerCenter) ✅@asispalazon (@CICbioGUNE) ✅María Liz Paciello (H. U. 12 Octubre) ✅María Rodríguez-Ruiz (@CIMA_unav) ✅Lucía Sanjurjo (@idis_research) 🪑@mogijon and @jon_zuga
#ASEICACongress
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Dubrot et al use genome-scale in vivo CRISPR screens to look at #immune_evasion mechanisms across #cancer models, showing that IFN-mediated upregulation of classical and non-classical MHC class I inhibitory checkpoints facilitate immune escape. https://t.co/CUgo7HMUbI
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We are looking for a PhD candidate to study the Structure and Dynamics of Complex Polymer-based Materials for Energy Storage applications under the supervision of @JonMaiz and #ArantxaArbe at @CFMdonostia @Ikerbasque. For more information:
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A CIC bioGUNE #study reveals the liver to be a target organ for #SARS-CoV-2 #infection 🦠 🔗 https://t.co/LjhbLmznS3
@chantarlab @asispalazon @upvehu @SaludISCIII @HospitalLaFe @upvehu @cimususc @univ_lille @Ikerbasque @brta_eus
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The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes ⬇️ SARS-CoV-2 pseudovirus infects hepatocytes causing metabolic reprogramming towards glycolysis &impaired mitochondrial activity @chantar_m @asispalazon @endi_air @mariamergom @CICbioGUNE
https://t.co/IrDAMWqhI9
nature.com
Communications Biology - SARS-CoV-2 pseudovirus infects human hepatocytes leading to metabolic reprogramming towards glycolysis and impaired mitochondrial activity, and metformin can reduce...
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