Arun Wiita
@apwiita
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#Pathologist @UCSF fighting blood #cancer & #genetic disease through #proteomics. Advocate for #PhysicianScientist trainees, my 2 kiddos, and work/life balance.
SF, CA
Joined May 2013
This 3D print is definitely raising the bar for parting gift from leaving lab members - thanks Tony!
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Excited about this new story from the lab @BloodPortfolio - CD70 is the next big #immunotherapy target in #myeloma! Check out @corynnkasap's Tweetorial to learn more
Excited to share our new manuscript, now published in Blood! BCMA #CART show impressive responses for #myeloma, but pts with high-risk cytogenetics relapse more quickly and are in urgent need of new therapies. Thread👇 (1/10) https://t.co/dR6jXxUxUa
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some GD T cell lymphomas are addicted to JAK-STAT signaling and relapse with new JAK-STAT mutations, much like melanomas to BRAF inhibitors. may represent new approach to treating these aggressive diseases. @jclinicalinvest
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Another fantastic & fun discussion here with @FaithEDavies1, @RascheLeo & @apwiita, who touched on novel targets in myeloma, CAR T-cells targeting novel membrane-based antigens & more! Thanks for joining us & stay tuned for these on https://t.co/O9p0vDBrzw soon🎥 #MMsm #HemOnc
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It's really cool that Tom Brady got to be there for the Eagles' two Super Bowl wins! He might be a good luck charm. Have a great night!
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Excited to moderate this @ASH_hematology discussion on the current and future of single cell technologies, and how they will inform precision medicine in #hematology. Please join us next Tues 2/11 11 am ET/8 am PT - registration is free!
Learn how single-cell technologies are revolutionizing blood cancer diagnosis and treatment with insights into MGUS, SMM, and AML therapy in the newest #precisionmedicine webinar! Register now: https://t.co/3k8AhIgqtb
#MedTwitter #Hematology #Leusm #MMsm
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Learn how single-cell technologies are revolutionizing blood cancer diagnosis and treatment with insights into MGUS, SMM, and AML therapy in the newest #precisionmedicine webinar! Register now: https://t.co/3k8AhIgqtb
#MedTwitter #Hematology #Leusm #MMsm
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So excited to start the year w/ our new paper @CellCellPress! #proteomics spatial map of human cells + dynamics using #organelle IP at scale. 🙌 to amazing teamwork @czbiohub and beyond. Check out portal https://t.co/Gb1TvlKcCH and paper https://t.co/YskVRBUqZi. 1/n
cell.com
Organelle proteomics defines the cellular landscape of protein localization and highlights the role of subcellular remodeling in driving responses to perturbations such as viral infections.
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New preprint! Our latest study identifying how MHC-I is captured by autophagy and targeted for degradation in #PDAC - It all happens at the ER ! Congrats to co-first authors @marineberquez @li_alexl & Matthew Luy. Details below 👇 https://t.co/pFgephVy8z
biorxiv.org
Pancreatic ductal adenocarcinoma (PDA) evades immune detection partly via autophagic capture and lysosomal degradation of major histocompatibility complex class I (MHC-I). Why MHC-I is susceptible to...
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For anyone in NYC this week, please be sure to check out Adam Dressner’s premiere art show “Hello Stranger” at Vanderbilt Hall at Grand Central Station! Great write up in @NewYorker - very proud of my friend of 26 years! I’m psyched to be there at opening
apple.news
Adam Dressner, who quit corporate law to become an artist—now with a solo show, “Hello Stranger”—heads to Washington Square Park to scout for subjects.
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We are excited to announce a faculty search in #Pediatric #Immunotherapy @UCSF❗️ We are seeking emerging or established leaders in the field of immunotherapy of pediatric cancers. PhD, MD, or MD/PhD candidates are all eligible! Please share widely.
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Our #FragPipe-Analyst manuscript is out! https://t.co/nJvHpfTAL2. Load FragPipe's TMT/ LFQ/DIA quant tables (peptide or protein quant) and get QC, Limma, PCA, volcano plots, heatmaps, do GO/pathway enrichment analysis, all with just a few clicks! Tutorials: https://t.co/9Bg2spF55D
pubs.acs.org
The FragPipe computational proteomics platform is gaining widespread popularity among the proteomics research community because of its fast processing speed and user-friendly graphical interface....
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New paper alert❗️ Want an ultrafast and easy way to label and quantify the extracellular proteome? Try out SLAPSHOT, using soluble APEX2 on live cells for extracellular #proteomics. Great story led by power duo @TtothepowerofT
nature.com
Communications Biology - Surface-exposed protein Labeling using PeroxidaSe, H2O2, and Tyramide-derivative (SLAPSHOT) coupled with mass spectrometry reveals the dynamics in the extracellularly...
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Recruiting a postdoc to study mechanisms of tolerance & immunity in the pregnant host. If you are passionate about this understudied area and excited to discover mechanisms of humoral tolerance to the placenta & fetus, do get in touch. (1/2)
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Thanks Salomon Manier and @BloodJournal for highlighting our recent work @HDMyeloma @SylvesterCancer @MSKCancerCenter #mmsm 🙏
Role and timing of chromosome deletions in multiple myeloma https://t.co/4BFWdv3hJD
#lymphoidneoplasia
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Never saw this coming
🍨Genentech is dissolving its cancer immunology group and its VP of cancer immunology Ira Mellman will leave the company Mellman, who discovered endosomes, led all cancer research at Genentech before focusing on cancer immunology https://t.co/d6dpuaKktX
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UPDATED: we have identified 313 (!) funding opportunities and fellowships for postdoctoral fellows. Download this database freely here: https://t.co/EbTahdzJ9X For each entry, we provide description, amount, deadline, eligibility, and link to funder. Good luck!
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in a fun collaboration with @KYTsaiLab, @zzreinstein has led a tour-de-force cellular and transcriptional dissection of Merkel cell carcinoma with a focus on predictors of response to immune checkpoint blockade. published today in @CD_AACR. https://t.co/wjlj5WNcQl
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