Andrew Ng
@andrewng_synbio
Followers
1K
Following
3K
Media
2
Statuses
254
Group Leader of Advanced Cell Engineering Lab at Genentech
San Francisco, CA
Joined March 2016
RT @GallowayLabMIT: Delighted to bring gene circuits into a wide array of primary cells where they can be used for safe, effective gene the….
0
50
0
Can’t wait to read this!.
🚨 New Preprint 🚨 .A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype. How can we tune JAK/STAT signaling to create better immune cell therapies?.
0
0
1
RT @aaronmring: You’ve heard of vibe coding—meet vibe protein design. Click, launch, and watch the binders roll in. That’s what we're unvei….
0
37
0
RT @Harvard: “No government—regardless of which party is in power—should dictate what private universities can teach, whom they can admit….
harvard.edu
No government—regardless of which party is in power—should dictate what private universities can teach, whom they can admit and hire, and which areas of study and inquiry they can pursue
0
30K
0
RT @Moon_Synth_Bio: Finally, this paper is out!.Cool paper by Chris Voigt, Yonatan Chemla et al. @Geneticdesigner @yonchem @NatureBiotech….
nature.com
Nature Biotechnology - Hyperspectral reporter genes allow imaging of ground bacteria from aerial vehicles
0
8
0
This was a wonderful collaboration with @labohaley and the lead authors Rajini and Tao. Grateful to have been welcomed into such a great group!.
0
0
2
Very proud to share this work from the Advanced Cell Engineering team at Genentech! We developed what we believe to be the best inducible CRISPR system yet that has nearly undetectable levels of leakiness and activation levels that match constitutive expression 🤩.
Our last pre-print of 2024! We created a simple-to-use, temporally-controlled CRISPR/Cas9 toolset that doesn’t compromise between background and induced editing.
3
22
199
RT @markwbudde: Are you a top-tier software engineer looking to solve real problems and accelerate biotech? Our talented and dynamic softwa….
0
22
0
RT @Moon_Synth_Bio: My best article @ScienceMagazine. It took ~1 year for me to publish it since its 1st submission. I hope it will positiv….
science.org
“I learned to spend more time trying than worrying,” this scientist writes
0
297
0
The stellar Matthew Kim is currently on the job market and on the hunt for Scientist roles in San Diego. He would make a great addition to any team! Many thanks to my perennial mentor and collaborator @HanaScientist for helping to guide this work to completion.
0
0
8
This work only scratches the surface of the world of circuits and applications that bioPROTACs have the potential to enable in cellular therapies. Excited and hopeful that others will find the tools we developed useful for their projects!.
biorxiv.org
Chimeric antigen receptor (CAR) T cells have made a tremendous impact in the clinic, but potent signaling through the CAR can be detrimental to treatment safety and efficacy. The use of protein...
1
0
14
🚨New Preprint🚨 We developed targeted protein degraders to degrade CARs and endogenous signaling molecules in T cells. The genetically encodable nature of these bioPROTACs enabled us to build a circuit to degrade ZAP70 and inhibit signaling in an antigen-dependent manner.
5
10
86
We have a second internship opportunity focused on iPSC engineering for a current PhD student in my group this summer! Get exposure to an industry environment and learn about practical applications of cutting edge genome engineering and synthetic biology.
0
8
23
We have an opening for a PhD student to participate in a summer internship with my team at Genentech. This is a unique opportunity to grow your genome engineering and synthetic biology skills while contributing to innovative drug discovery research.
5
70
185
Exciting news - I've joined Genentech to lead the Advanced Cell Engineering Hub, and we are growing our team! We are seeking a Scientist 3 to advance next-generation methodologies and applications in iPSCs and primary cell models. Please share and apply!
4
17
136
RT @ProfTomEllis: An under-rated aspect of synthetic biology research is that we rarely need to care about stats and p-values because we bu….
0
18
0
RT @stevenschem: Our paper, “Programming multicellular assembly with synthetic cell adhesion molecules” is now online ahead of print. https….
nature.com
Nature - Synthetic cell adhesion molecules yield customized cell–cell interactions with adhesion properties that are similar to native interactions, and offer abilities for cell and tissue...
0
35
0