Katie Galloway
@GallowayLabMIT
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Assistant Prof @MITChemE ; mom^4 + wife; enjoys building cell-fate circuits, exploring dna topology, reprogramming the living world, and soccer; soli gloria deo
Joined June 2019
🤔How do you design a promoter for stable titration of expression? 💡Try programmable promoter editing with DIAL! 📰Now published at @NatureBiotech 🧵 [1/n] 🔗 below
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Enjoyed the tweetorial? Want to hear more? Come hear @emmapeterman_ live at AIChE this coming Thursday. Details 👇 Thursday, November 6th, 2025 Session #654: Cellular, Protein, & RNA Systems Engineering 8:00 AM, Hynes Convention Center, 310
So you want to change transgene expression: just change your promoter, right? Changing the promoter increases RNA and thus protein levels. What more could be happening? [1/n] Well, promoters don’t just set RNA levels; they uniquely transform how RNAs are transmitted into protein
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If you are thinking about ditching health insurance all together but are worried about going completely naked in the case something big comes up, you should give CrowdHealth a look. Here is what our CrowdHealth members have paid on average/month over the last 12 months: $143
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Enjoyed the tweetorial? Want to hear more? Come hear @science_sneha live at AIChE this coming Wednesday. Details 👇 Wednesday, November 5th, 2025 Session #543: Genomic & Genetic Engineering Technologies 2:00 PM, Hynes Convention Center, 310
🤔How do you design a promoter for stable titration of expression? 💡Try programmable promoter editing with DIAL! 📰Now published at @NatureBiotech 🧵 [1/n] 🔗 below
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BE Seminar Series this Thurs w @BugajLab, @pennbioeng “Using Light, Temperature, and Protein Condensation to Understand and Control Cells” https://t.co/S4OMf9QxjQ
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Come see @SuYapeng at #AICHE2025 future faculty poster session! 👇
@GallowayLabMIT Board number 213. Poster number 3hn. Looking forward to reconnecting 🤩
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One of the first women to become a physician in Britain was Elizabeth Garrett Anderson (1836-1917). She received education on the wards as a nurse, and then established herself on the medical register through the Society of Apothecaries. She founded the London School of Medicine
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@GallowayLabMIT Board number 213. Poster number 3hn. Looking forward to reconnecting 🤩
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super interesting read! looking to dig in more! Nice work @GeneticsMike7 ! TL/DR seems like transcriptional control didn't work here, so you all switched to splice-mediated control. is that about right? very nifty! Congrats!
1/ Happy to share important work done with my co-author Andrew Khalil in the labs of Rudolf Jaenisch @WhiteheadInst @MITBiology @MIT and Dave Mooney @Harvard @wyssinstitute trying to assess and fix the major problem of transgene silencing in human ESC/iPSC based work
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Presenting at the #AICHE2025 Future Faculty poster session today? Drop your details in the thread below! Happy to RT! See you there! @ChEnected @MITChemE
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Jetoptera’s Fluidic Propulsive System™: Bladeless, quieter, 2-3x faster than a helicopter and 2-3x thrust augmentation. Powering fast, efficient VTOL UAS & aircraft for cargo and people. Join the future of flight!
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It's great to be back in Boston for the #AIChE #AIChE2025 #AIChEAnnual conference this week! If you’ll be there, I’d love to connect. I'll be presenting on Monday and Thursday: 🎯 Talk: Data-Driven Strategy Selection for Multi-Fidelity Modeling in Autonomous Molecular Discovery
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Enjoyed the tweetorial? Want to hear more? Come hear @emmapeterman_ live at AIChE this coming Thursday. Details 👇 Thursday, November 6th, 2025 Session #654: Cellular, Protein, & RNA Systems Engineering 8:00 AM, Hynes Convention Center, 310
So you want to change transgene expression: just change your promoter, right? Changing the promoter increases RNA and thus protein levels. What more could be happening? [1/n] Well, promoters don’t just set RNA levels; they uniquely transform how RNAs are transmitted into protein
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Enjoyed the tweetorial? Want to hear more? Come hear @science_sneha live at AIChE this coming Wednesday. Details 👇 Wednesday, November 5th, 2025 Session #543: Genomic & Genetic Engineering Technologies 2:00 PM, Hynes Convention Center, 310
🤔How do you design a promoter for stable titration of expression? 💡Try programmable promoter editing with DIAL! 📰Now published at @NatureBiotech 🧵 [1/n] 🔗 below
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5/ What drives the selective sequestration of mRNAs in P-bodies? We found that certain cell-type–specific microRNAs are enriched in P-bodies and modulate RNA sequestration. Disrupting microRNA–target interactions prevents the corresponding mRNAs from being sequestered.
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Selective RNA sequestration in biomolecular condensates directs cell fate transitions https://t.co/Du9Ytd5qRB
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1/ Excited to share our new study with @Brumbaugh_JB, now out in @NatureBiotech! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 https://t.co/D7fnkJgNQ6
nature.com
Nature Biotechnology - Stem cell differentiation is controlled by manipulating RNA condensates.
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Coming soon the 2026 meeting... see link below for the 🔥speaker line up!
⏰Tick-tock!⏰ Abstract deadline for SynBio for Future Health Jan 17th #synbio Heads up to @MoKhalilLab @RosserLab @barbara_synbio @LeonardoMorsut @rjerala @XueSherryGao @SynBioGaoLab @ElowitzLab @genegirl007 @BintuLacra @TheLeonardLab @Geneticdesigner @kunjapur @ProfTomEllis
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Don’t miss our next BCDI meeting! 🧠GPX4 in neurodegeneration—Adam Wahida (Helmholtz-Munich; visiting @MGHCancerCenter, @HarvardChanSPH) 🧬 Targeting phosphate homeostasis in cancer—Daniel Bondenson (@UMassChan) 📅 Mon Nov 3 | 3PM | @harvardmed Quad 🔗 https://t.co/sl332L9g5I
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🥳Congrats to @science_sneha who lead this project and coordinated the team – Yunbeen, Mary, Brittany, Adam, Emma, Kasey, and Deon—who helped us cross the finish line! Excelsior! [15/n]
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đź’µThanks also to our funders NIH, NSF, AFOSR, ICB (Army). We truly could not have done it without their support and we are very grateful especially in these challenging times! [14/n]
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🙏Thanks to the team at NBT @NatureBiotech especially Barbara Cheifet, our editor, who helped us develop this story and get good, constructive feedback which helped improve the story and the tools! [13/n] https://t.co/cxGxZFd31R
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