Alexis Combes
@alexis_combes
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Immunologist and team science advocate, Assitant Professor and Disease to Biology CoLab (D2B) Director at @ucsf @immunox https://t.co/NjmuupTC34…
San Francisco, CA
Joined October 2020
Online today @CellCellPress. By identifying and classifying recurrent immune features, we discovered 12 unique dominant tumor Archetypes that span cancer types. This immune-based classification provides a framework toward understanding tumor immunity to guide immunotherapies 1/n.
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Thrilled that this is out. The results of an incredible collaboration which started 5 years ago and was made possible by @immunox and the @UCSFCoLabs model. Thanks @MikeKattahMD and team to have embarked us with you on this OMICS rollercoaster . Looking forward to more together.
Excited to share our manuscript on single-cell and spatial multi-omics of anti-integrin therapy in ulcerative colitis (UC) This work was led by @ElviraMennillo, in collaboration with @alexis_combes, @GabiFragiadaks, and @drAOPisco 1/8
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RT @KellyKersten8: I’m hiring a postdoc and SRA for my new lab at @sbpdiscovery in San Diego, CA! Are you passionate about dissecting the i….
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RT @RayArja: Are so-called 'M2-like' CD206+ macrophages immunosuppressive? On the contrary, we find that they are critical for T cell media….
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RT @gaiaandreoletti: I am pleased to announce that our research on transcriptomic data analysis of XLMTM has been published today in @AJHGN….
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You are using unsupervised clustering to analyse high dimensional cytometry data and always wonder what is the correct number of clusters. We do too! To help this process we developed Cyclone👇. Wonderful collaborative effort with @GabiFragiadakis lab!.
Our new pipeline with @alexis_combes @sciRPatel and Rebeca Jaszczak out now! Cyclone: an accessible pipeline to analyze, evaluate, and optimize multiparametric cytometry data
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🎉Our Cancer immune archetype perspective is on @NatureRevCancer's July cover!. We're seeking a #postdoc to unravel the cellular networks and gene programs behind these archetypes. If you're fueled by passion for immunology and oncology 👉Please RT🙏
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RT @MaxKrummel: Our lab ( is hiring a bioinformatics-minded person for the Immune Archetypes project.See it here:….
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To decode the immune system, time and place is of the essence. Inspiring work by @KenHu77 @nicholasfkuhn and @MaxKrummel. I’m glad we were able to participate to this.
Happy to share our work w @nicholasfkuhn on identifying spatiotemporal patterns of gene programs in the healing wound is live @CellStemCell : A pithy summary:.
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Thank you for the invite @ElviraMennillo really looking forward to it!.
We warmly invite you to join us for the career panel event! This will be a great opportunity for postdocs and trainees to hear from young scientists in immunology! #immunox #winterfest #ucsf #parnassus
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Excited, (and let's face it a bit stressed) to talk about immune states in cancer at the #Tandem23 meeting tomorrow morning during the tumor microenvironment session. Feel very lucky to share the session with two top scientists in the field Catherine J Wu and @elhamazizi.
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Feel very lucky and humbled to be part of this new org surrounded by amazing people who want to get together to achieve BOLD goals and change the culture of science. Check it out!.
We’re also proud to share with you the official launch of our brand new organization, Solving for Science. We have a revolutionary goal, read all about it:
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3 super days in Bonn for #EMDS2022. Amazing science with incredible colleagues and great opportunity to catch up with old friends and meet new ones. Thanks to organiser for the opportunity to share our work with this crowd!
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Great and inspiring time at the UCSF @immunox/@UCBerkeley immunology retreat with incredible colleagues and trainees. Proud of the lab crew who rocked at the poster session. if you are interested in dissecting immune cell networks in Cancer, the lab is expanding, come join us!
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RT @SpitzerLab: We are hiring a lab manager! Come join our collaborative and dynamic team and lead an exciting project in cancer immunother….
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If you know someone who is looking for a research experience in translational immunology they must apply! Dynamic group in very collaborative environment @UCSF led by an amazing physician-scientist.
We are hiring! My lab is looking for a research technician (SRA II) to help with our IBD-related research projects, including mouse models of disease and translational multi-omics studies. Job description and link to apply here: •@ucsfibd @alexis_combes.
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RT @RafaJArguello: The results of grant @AgenceRecherche are out!!! 🥳🤩🤩 . Very happy to get the our MetaNiche Project @Perielab1 @cosgrove4….
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Great opportunity to play a central role in a large industry-academic research initiative aiming to better understand the underlying mechanisms of autoimmune diseases. please RT.
I am one of the leaders on a large industry-academic research alliance, called the AutoImmunoprofiler Consortium, and we are looking for a Project Manager! See job description here:
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I'm thrilled to see this out! A must-read if you are interested in the multicellular network regulating the anti-tumor immune response. Congrats @KellyKersten8 @KenHu77 @MaxKrummel and all co-authors.
So excited to share that our paper describing the cross talk between TAM and exhausted T cells is available online today! #TME #immunotherapy Thanks again to the entire team @MaxKrummel Check this link:👇
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A wonderful collaboration a very insightful paper led by @Marie_Laviron and @BoissonnasLab combining single-cell RNAseq and intravital imaging to better understand tumor-associated macrophages in breast cancer. Check it out!.
If you want to understand a bit more on TAM heterogeneity check out @Marie_Laviron 's paper:
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RT @KarlKochanowski: Come work with us! We have an opening for a 3y PhD project @CReSA_r centered around metabolism and microbial interacti….
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