📢Greetings! We are accepting submissions for 'Systemic immune response through a multi-omic lens' @FrontImmunol Please share this with anyone working on #systemsImmunology #immunology #multiomics #integrativeAnalysis #infectiousdisease #autoimmunity

Steroids have *compartment-specific* effects in patients with COVID-19 ARDS! Results highlight importance of studying injured organs directly when possible @NatureComms with Lucile Neyton, @sciRPatel, @GabiFragiadakis and colleagues https://t.co/BHQnnkZd9l

I am excited to share that our #IMPACC paper - Integrated longitudinal multi-omics study identifies immune programs associated with acute COVID-19 severity and mortality - was recently published in @jclinicalinvest. https://t.co/uxzRhq3yLL #SystemsBiology #Bioinformatics [1/5]

Excited to share our manuscript on single-cell and spatial multi-omics of anti-integrin therapy in ulcerative colitis (UC) https://t.co/QEFgIMVVOe. This work was led by @ElviraMennillo, in collaboration with @alexis_combes, @GabiFragiadaks, and @drAOPisco 1/8

Not at all jumping on the AI rodent band wagon, but delighted to announce the publication of our paper in @MucosalImmunol about why you lose your appetite when you have a cold https://t.co/HBE0o5IDwP Including the coolest experiment I have ever done

New research in mice finds that neonatal CD8+ T cells can undergo rapid chromatin remodeling, which supports their innate-like functions. Read more: https://t.co/1dNPVhPKYk @Cornell @CornellCFI

@SciImmunology This paper is beautiful ➡️ https://t.co/E5CbtQTKYp To be paired with this vintage 💎 https://t.co/r7APx25fMC

A new @SciImmunology study describes why a subset of T cells behaves in a way that is more similar to innate immune cells, rather than responding like normal adaptive immune cells. Learn more: https://t.co/acE3DLXeRj

4) 'Keep the child within us alive'. Highly reactive, innate-like T cells of childhood are also found in adulthood in both mice and humans, changing how we think about the T-cell biology in adults. (5/5)

3) Neonatal CD8+ T-cells provide protection against bacterial, viral and parasitic pathogens. (4/5)

2) Innate-like properties of a subset of neonatal CD8+ T-cells during bystander activation that is driven by a balance of #TranscriptionFactors Bach2 and AP-1 activity. (3/5)

1) A functionally diverse pool of CD8+ T-cells that may compensate for the primitive adaptive immune system of neonates. (2/5)

How do neonates with primitive immune system survive in the world? We found: (1/5) @SciImmunology (in Rudd & Grimson labs; with Neva & Connor, fellow Tweeters @Oyeb2003 @CybelleTabilas @kristel_yee @eliataitwojno) #SingleCell #multiomics #neonatalImmunity

'Keep the child within us alive'. Highly reactive, innate-like T cells of childhood are also found in adulthood in both mice and humans, changing how we think about the T-cell biology in adults https://t.co/rR7twMGdTd @SciImmunology #SingleCell #multiomics #neonatalImmunity

How do neonates survive with primitive adaptive immune system? Read about the functionally diverse pool of CD8+ T-cells that may compensate for the primitive adaptive immune system of neonates. https://t.co/rR7twMGdTd @SciImmunology #SingleCell #multiomics #neonatalImmunity

Read about another fantastic collaboration of Rudd-Grimson lab on innate-like CD8+ T-cells in mice and humans.

The newest story from the Rudd lab is out! Read about how CD8+ T cells are more than just their T cell receptor! Congrats to @sciRPatel et al

A new study in mice describes the activation programs of neonatal innate-like CD8+ #TCells, spotlighting the roles of #TranscriptionFactors Bach2 and AP-1. Learn more: https://t.co/YPacE635v1 @Cornell @CornellCFI

Excited to present a team of fantastic co-editors @ElviraMennillo, @JoannDArce, & @Chevaliersf.

Excited to share a call for submission to a topic 'Systemic immune response through a multi-omic lens' @FrontImmunol. Please share this with anyone working on #systemsImmunology #immunology #multiomics #integrativeAnalysis #infectiousdisease #autoimmunity