Abhinav Jain, Ph.D.
@abhinavjain_phd
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Associate Professor, Epigenetics & Mol. Carcinogenesis || Co-director, Epigenomics Profiling Core at The UT MD Anderson Cancer Center
Houston, TX
Joined February 2023
Much needed indeed, Congratulations Nick @NicolasLYoung !!
Today, we introduce a nomenclature that can express discrete PTMs, proteoforms, nucleoforms, or situations where defined PTMs exist in an uncertain context and can describe how proteoforms are configured in functionally distinct complexes across biology. https://t.co/WrMYTXamIe
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This is a fantastic and comprehensive review on cell free DNA fragmentomics in cancer. Out in @Cancer_Cell
https://t.co/4qR6IF1w8G
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Congratulations and welcome back Mehrnoosh @TashakoriM !!
After 4 incredible years at the Univ of Minnesota, I’m thrilled to share that I’ve joined MD Anderson as a tenure-track faculty member in #Hemepath. Grateful for the amazing team I’m leaving behind and excited for this new chapter at my academic home! #EndCancer
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Congratulations Vallerie and the team!!
Heavy lifting by @Val_LeBleu @drsmags @DrShubhamPant @EJShpallMD @Aiims1742 @rkalluriMDPhD @krishnaniyer199 @mcandrews_kate @loukirtley @cara_haymaker @MikeGagea @abhinavjain_phd @rachnatshroff and other co-authors not online 🤩
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Congratulations to my superstar friend @SGoswamiMDPhD!
Thank you so much for the recognition. I truly appreciate it. @ppisters @AnneTsao2 @CarinHagberg @MDAndersonNews
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Inspiring as always! Keep it up @SGoswamiMDPhD
“The lab and the clinic may seem like two different worlds, but when they come together, that’s where transformation happens — for science, for medicine, and most importantly, for patients." 5 reasons the physician-scientist path was right for me https://t.co/pD9hIwSHTw #
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Congratulations @lab_rezvani @HindRafei & the entire team!!. A privilege to contribute to such an impactful study #NK #epigenomics
Please check out our paper published today in Nature that identifies CREM as a key checkpoint limiting CAR NK cell function.CRISPR knockout of CREM significantly enhanced anti-tumor activity, implicating a broader role in NK cell regulation. Huge congrats to @hindrafei and our
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🧵1/ T cells have deservedly been in the🔦for #cancer #immunotherapy, but other engineered cell therapies are now📈. What mediates NK cell exhaustion remains an important unanswered❓. 📄Link: https://t.co/dQIK4fVkxO I’m so thrilled🥳to share our work out now🚨@Nature
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Awesome!! Another impactful discovery from @lab_rezvani. Many congratulations @HindRafei for leading this work and your immense hard work! So glad to contribute to this important study #epigenomics #Nkcells @MDAndersonNews
🧵14/ This work wouldn’t have been possible without the incredible mentorship of @lab_rezvani, the brilliance of our lab members, our co-authors, and the generous support of our collaborators Dr. Toszka Bohn, Dr. Tobias Bopp, Sebastian Kunz, Dr. Huihui Fan, @abhinavjain_phd,
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Fantastic proof of concept. Congratulations Hussein @HusseinAbbasLab & the team!!
Huge props to Chris Ly, @iveletic and the whole team after a ton of trial-and-error, to perform high-throughput spatial CyTof and Lunaphore on bone marrow samples in AML. Just the beginning of this proof-of-concept work.
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Wow…an incredible legacy on the move. Thank you Dr. Maitra for your guidance and support, and many Congratulations on this next phase. We will miss you here @Aiims1742
After 12 years, I am sad to leave the many collaborators & friends I have had the good fortune to work with at @MDAndersonNews. Especially grateful to @DraettaG @skopetz @rkalluriMDPhD @IamLinghua @timheff5 @RonDePinho & MANY others for being such incredible partners in research!
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This is great. Congratulations Ece @EceEksi1
Exciting new method in #cancerneuroscience: we're modeling nerve-cancer interactions in 3D using microgels! This is a fun collab with the Bertassoni lab, who's been doing amazing work with the Biofabrication Hub @OHSUKnight: https://t.co/6h18tFG5NN
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Congratulations @Aiims1742 @IamLinghua and the team.
Congratulations to @IamLinghua @GuangshengPei @jiminmin_v and all our exceptional collaborators at @MDAndersonNews & beyond for today's study in @Nature on spatial mapping of transcriptomic plasticity in metastatic #PancreaticCancer The full text link is
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Will miss it, I’m sure it will be great. Congratulations!! @HindRafei
Very excited to share our work on targeting a checkpoint induced by CAR and cytokine signaling and exchange ideas at the Adoptive Cell Therapies session co-chaired by @sidichen @DJPowellLab at #AACR25. I hope to see you there 😊! @lab_rezvani @MDAndersonNews AACR: MD Anderson
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Many congratulations, May, Simona & the teams!! @may_daher @CollaSimona
Very excited to share our latest research article published with @SpringerNature in @NatureComms. We show that in early #MDS, NK cells share mutations with the malignant clones, becoming dysfunctional and failing to eliminate aberrant stem cells. This leads to immune evasion and
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Congratulation! @lab_rezvani & the team!!
Please check out our paper published in @NatureMedicine on our Phase I trial of AFM13-precomplexed cord blood NK cells in relapsed/refractory CD30+ lymphomas. Led by Dr. Yago Nieto and an outstanding team of coauthors and collaborators, this study marks the first clinical
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Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq | Nature Protocols
nature.com
Nature Protocols - In this Protocol Extension, the authors describe procedures for spatial barcoding in tissue sections using a microfluidic chip followed by sequencing-based joint genome-wide...
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We're so thrilled to finally share with you the published version of our CUT&Tag optimization and benchmarking paper "CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks" - out in @NatureComms today:
nature.com
Nature Communications - Cleavage Under Targets & Tagmentation is a rapidly expanding technique, but thorough evaluation and benchmarking against established ChIP-seq datasets are required....
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It was a pleasure to showcase our lab’s expertise in assays for DNA-protein interactions (ChIP & CUT&RUN), chromatin accessibility & more at #ABRF2025. A great discussion on how facilities like our’s, Epigenomics core @MDAndersonNews is making impact to support research missions.
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