Nicola Murdoch
@_nicolamurdoch
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final year phd in the CPJ group @ St. Andrews. interested in catalysis + radicals, with a side of gin, long walks & cooking✨views are my own. she/her
St Andrews
Joined February 2021
Rational Design of PROTAC Linkers Featuring Ferrocene as a Molecular Hinge to Enable Dynamic Conformational Changes | Journal of the American Chemical Society @alessiociulli @Dundeeuni @UoDCeTPD. @AmphistaThera
pubs.acs.org
Proteolysis Targeting Chimeras (PROTACs) are bifunctional molecules that induce ubiquitination and degradation of a target protein via recruitment to an E3 ligase. The linker influences many steps of...
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. @JOC_OL (open) Simple Parameters and Data Processing for Better Signal-to-Noise and Temporal Resolution in In Situ 1D NMR Reaction Monitoring, Annabel Flook @aannabelflook Guy C. Lloyd-Jones* @LloydJonesLab @EdinburghChem
https://t.co/zulpmnmfv4
#NMR #NMRchat 🧲
pubs.acs.org
In situ 1D NMR spectroscopic reaction monitoring allows detailed investigation of chemical kinetics and mechanism. Concentration versus time data are derived from a time series of NMR spectra. Each...
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C-B, or not to C-B - that is the question… Check out our review on the utility of multiborylated alkanes in @NatRevChem. Huge congratulations to @KaneACB and @D_Roberts95 for their fantastic efforts! @EPSRCboron @StAndrewsChem
https://t.co/ZvbWL1I0Ni
nature.com
Nature Reviews Chemistry - Monoborylated alkanes display diverse reactivity and broad application; however, despite an increasing number of approaches to access them, multiborylated alkanes have...
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A pleasure to get the opportunity to present some of my PhD work on cobalt-catalysed Wagner-Meerwein rearrangements at the @EuChemS_Congres. Had such a great time attending talks, learning some new chemistry and having the occasional pint of Guiness! Dublin, you’ve been grand☺️
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A new element makes its way into the Watson Group repertoire! Check out our first foray into the world of germanium in the context of CuAAC chemistry, in collaboration with @BurleyResearch! The pre-print is available here on @ChemRxiv: https://t.co/q2axaO2SaO
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Had a wonderful time in Cardiff on Friday at the @SCIupdate Postgraduate Symposium! Great to see the amazing work done by so many extremely talented PhD students! I was also honoured to receive a first-place prize for my presentation talking about the @LarrosaGroup new catalyst!
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Link to the issue:
Starting off the year with some exciting news! Thrilled to say my first ever cover art is on the cover of Chemical Reviews this month! Our review was submitted as part of a thematic issue about late stage functionalisation, go check it out if you haven't already :) @LarrosaGroup
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Starting off the year with some exciting news! Thrilled to say my first ever cover art is on the cover of Chemical Reviews this month! Our review was submitted as part of a thematic issue about late stage functionalisation, go check it out if you haven't already :) @LarrosaGroup
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Congrats to our senior member Jez, who is now a true master of both aspects of the photo-venn diagram…
Jeremy’s paper on photocatalytic cross-coupling of styrene boronic acids is published in @angew_chem. Congrats Jeremy! @watson_group @StAndrewsChem @EPSRCboron
https://t.co/NkgqYh4HID
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Jeremy’s paper on photocatalytic cross-coupling of styrene boronic acids is published in @angew_chem. Congrats Jeremy! @watson_group @StAndrewsChem @EPSRCboron
https://t.co/NkgqYh4HID
onlinelibrary.wiley.com
We report a rare polarity-mismatched radical addition reaction using styrene boronic acids and redox-active N-hydroxyphthalimide (NHPI) esters under photoredox catalysis. The reaction displays broad...
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Delighted to share the use of chemistry developed in the @watson_group to generate complex aryl BMIDAs!
John’s method for making aryl BMIDAs via [2+2+2] is now out in @ChemCommun. Congrats @john_mcguff! https://t.co/WEJjH4gFNX
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Our first foray into photoredox exploiting some unusual boron reactivity is now on @ChemRxiv. Congratulations Jeremy! https://t.co/X3WYoFV0mV
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Column chromatography as flags of the world: Thread
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Academia meets Industry: A breakthrough catalytic asymmetric synthesis of cannabinoids and menthol from neral in the shortest and most atom-economic route so far @Nature Read the story here:
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Our study of the internal alkyne problem in Rh-catalysed [2+2+2] cucloadditions is out in @ACSCatalysis. Huge congrats to @john_mcguff on an enormous amount of work! @watson_group @StAndrewsChem
pubs.acs.org
The Rh-catalyzed [2 + 2 + 2] cycloaddition of diynes and alkynes is a synthetically useful transformation that rapidly constructs complex scaffolds and has been used extensively for >70 years....
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Excited to see this one out 🤟 Check out our group's latest advance in C–N coupling! https://t.co/2F9wEOqWp9
pubs.acs.org
We report a versatile and functional-group-tolerant method for the Pd-catalyzed C–N cross-coupling of five-membered heteroaryl halides with primary and secondary amines, an important but underexplo...
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Many congratulations to all the winners and runners-up for the lectures and poster presentations at the postgraduate symposium @StAndrewsChem. Thanks again to our wonderful sponsors @Asynt @Biotage @RoySocChem @IscoUk @HuberTechUK @ShimadzuUK @Merck @ApolloSciUK @thermofisher.
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