Sarah Nicolas
@_Sarah_Nicolas
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Lecturer @AnatNeuroUCC @Pharmabiotic #neuroscience #neurogenesis #neuroinflammation #hippocampus #exercise #microbiota #gutbrainaxis
Cork, Irlande
Joined September 2017
New APC research from @UCC published in @BrainMedJournal suggests Exercise helps Protect the Brain from Junk Food. Authors: @MinkeNota @_Sarah_Nicolas Sebastian Allard Dohm-Hansen, Erin Harris, Tara Foley, @oliviafoleary @yvonnemnolan ▶️ https://t.co/z7jeZXxg3f
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APC is recruiting a Post-Doc to work with Prof Yvonne Nolan at @UCC Work with a team investigating the role of gut microbiota in the effects of diet, exercise or cognitive interventions on cognition and mood in older aged people with depression. Details: https://t.co/X6QXQyys27
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Next up is Zoe Williams @UCC talking about ‘Exercise reduces neuropathology in mouse model of #Alzheimer's disease via the gut microbiome". @UCCResearch @UCCMedHealth #APCSymposium2025
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Congratulations to APC's Zoë Williams @UCC who won 'Student Oral Presentation' for her talk 'Biological Sex Influences Exercise-Induced Changes in Memory, Mood & Neuropathology in a Mouse Model of Alzheimer’s Disease' at the @UCCMedHealth Annual Research Conference @Researchirel
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Happy to see published the last piece of a fruitful (and fun!) collaboration on Adiporon,from depression to osteoporosis: The adiponectin agonist AdipoRon accelerates osteoporosis development in two different models and modulates adipocyte differentiation
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Characterizing plaque-associated #microglia (PAM) and non-plaque-associated microglia (non-PAM) in a mouse model of Alzheimer's disease; non-PAM modulate cell population expansion in response to amyloid deposition and rapidly respond to environmental cues https://t.co/8o6B4Xl9yP
nature.com
Nature Neuroscience - The dynamics of microglia states adjacent to or far from amyloid-beta plaques are unclear. Here the authors show that non-plaque-associated microglia modulate the cell...
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I read this Cell paper that argues to have discovered a molecule (betaine) that mimics the geroprotective effects of exercise. This is a very valuable multi-omics resource, but the authors seemed to get caught in the rabbit hole of chasing a high-impact narrative🧵
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Join us this Thursday at 1pm on Zoom for this exciting panel event! Register here https://t.co/9J3QIqkguS
docs.google.com
Hello Everyone, Join us for our Career Progression in Academia Seminar. This event brings together voices from every stage of the academic ladder—from a recent PhD graduate, to a current postdoctoral...
🔊 Join us on Thursday, June 19th at 1PM (Zoom) for our Career Progression in Academia seminar! 🎓 Hear real advice from researchers at every career stage—from PhD to professor. Perfect for early career researchers! 🔗Registration and Zoom link: https://t.co/u0fuK2Dykr
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🚀#Pint25 in #Cork 🧠 🚺 🦠 The Gut-Brain Axis: How Your Microbes Talk to Your Mind 📅May 19th 📍The Roundy Interested in microbiome, women's health, lifestyle changes and Alzheimer's? FREE ticket here: https://t.co/qR84nbzuOg
@pintofscienceIE @Eoflat
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@AmieeMCronin, @zapwilliams, and I will talk about the involvement of gut microbes in various neurological processes in just over a week! 🦠 @pintofscienceIE
🚀#Pint25 in #Cork 🧠 🚺 🦠 The Gut-Brain Axis: How Your Microbes Talk to Your Mind 📅May 19th 📍The Roundy Interested in microbiome, women's health, lifestyle changes and Alzheimer's? FREE ticket here: https://t.co/qR84nbzuOg
@pintofscienceIE @Eoflat
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Delighted to be a speaker for Pint of Science Cork! Come grab a pint and learn about how your gut microbes can impact your mental health🦠🧠 https://t.co/mrInefHNgc
#Pint25
pintofscience.ie
The brain is an elusive organ, endlessly complex and yet always fascinating. While the brain might seemingly tell the whole body what to do, this communica…
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Signalling from adipose tissue to the brain is not just about leptin
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📢 New paper : Amygdala hyperactivity is a hallmark of anxiety, but how it happens remains a mystery. Using a mouse model of social stress, we uncovered key mechanisms behind this shift. Amazing collaborators in Bordeaux, Baltimore, and Buenos Aires 🧠⚡ https://t.co/JT1Fzy6oII
biologicalpsychiatryjournal.com
Brain defensive mechanisms evolved to maintain low levels of state anxiety. However, risk factors such as stress exposure shift activity within defensive circuits, resulting in increased anxiety. The...
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Sex, not estrous cycle stage, drives differences in the microglial transcriptome in the 5xFAD mouse model of amyloidosis https://t.co/MRfIeBhzRa
biorxiv.org
Alzheimer’s disease (AD) presents with a sex bias where women are at higher risk and exhibit worse cognitive decline and brain atrophy compared to men. Microglia play a significant role in the...
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Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST https://t.co/JmrhCPxx2e
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