Sara Zanivan
@ZanivanLab
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Cell biologist, passionate about tumour microenvironment, CAFs, metabolism and MS-proteomics. Tweets are my own @CRUK_SI 🇪🇺
Glasgow, Scotland
Joined February 2012
Thrilled to see our latest work “Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function” led by Alice Santi and @emilyjkay1 on the cover of @scisignal. Beautiful images by @BairBeatson Paper here 👇🏻 https://t.co/Vs2Dj2ByQM
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We’re hiring a postdoc (≤2 yrs experience) with strong expertise in metabolism to study metabolic regulation of stroma–immune interactions in our lab @MDAndersonNews. Only qualified applicants will be considered 👇 https://t.co/WWbgVgYgXR
lnkd.in
This link will take you to a page that’s not on LinkedIn
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Excited to share the lab’s first pre-print! Here we investigate how #nutrient availability regulates #ECM composition, mechanical properties and biological activity. https://t.co/X6JGY4KIwP
biorxiv.org
The extracellular matrix (ECM) provides key biochemical and biomechanical cues that govern fundamental cellular processes, including growth and migration. ECM dysregulation and altered cell-matrix...
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📢Are you a talented #ECR looking to start your independent lab in state-of-the-art cancer research facilities? Join the CRUK Scotland Institute & @UofGCancerSci as a Junior Group Leader! 👉Find out more and apply here: https://t.co/8Qs1yLwOze 📅Closing date: 10 October 2025
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We are looking for a talented Postdoc to join our Lab @MDAndersonNews ! If you're interested in metabolism, tumor microenvironment, and cutting-edge MS proteomics, and have less than 2 years Postdoc experience, look here 👇 https://t.co/A5umv2Os1Y
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If you are interested to learn more about CAFs , read this great mini-review by @FerKugeratski and @emilyjkay1 👇🏻
For those interested in the role of cancer-associated fibroblasts in the tumor microenvironment, please check out our review focused on recent discoveries related to CAF biology in the context of immunotherapy, metabolism, and extracellular vesicles:
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For those interested in the role of cancer-associated fibroblasts in the tumor microenvironment, please check out our review focused on recent discoveries related to CAF biology in the context of immunotherapy, metabolism, and extracellular vesicles:
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We received the cover for our recent publication in @CCR_AACR. This multi-institutional study offers the first systematic proteogenomic analysis of synchronous endometrial and ovarian cancers (SEOC). Read: https://t.co/bBE0uX2SXU
@OvCa_UChicago @Mad_PhD @labs_mann
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We welcome Sieun Lee to our growing Lab @MDAndersonNews with @FerKugeratski and Amari Sockwell! Look forward to seeing where her research will drive us on understanding immune-regulatory roles of CAF metabolism in cancer
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The new ZanivanLab 2.0 @MDAndersonNews is growing 😃! After @FerKugeratski joining as an Instructor since day 1, we welcome Amari Sockwell as senior research assistant. And the lab is almost functional, so…lot of new research coming soon! #TME #CAF #Proteomics #metabolism
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Making space for spatial biology in the clinic Spatial transcriptomics methods have been slow to move into clinical practice, but spatial proteomics are cheaper and more scalable, and could progress faster https://t.co/0ff7OMxexN
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One of the best Symposium i have been to, lot of insights on the future of how to get to using proteomics into the clinics! Also excellent atmosphere, great discussion! Strongly encourage to ready it 👇🏻
The 68th Benzon Symposium report is now online in @molcellprot ! Fantastic conference that brought together top global experts in Copenhagen to translate proteomics to the clinics - from technological advances to regulatory frameworks! @labs_mann
https://t.co/F3EZcUo84E
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The 68th Benzon Symposium report is now online in @molcellprot ! Fantastic conference that brought together top global experts in Copenhagen to translate proteomics to the clinics - from technological advances to regulatory frameworks! @labs_mann
https://t.co/F3EZcUo84E
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📣I am very excited to announce that our lab is moving (very soon) to MD Anderson in Houston! If you share our passion for #TME #CAF #metabolism, cutting-edge #MSproteomics, and are interested to join us for a postdoc, please contact me!
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Looking forward to it! 👇🏻
Discover the life-changing opportunities of studying abroad! 🚀 Join us for an inspiring panel discussion with incredible speakers @ZanivanLab, @BartVP, and Joern Dengjel on Oct 2nd at 3 pm. Don't miss out - register now:
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Great to be part of this special issue. Thank you very much @CR_AACR for the opportunity to write about our favorite cell type 💜. A fantastic job from @GianlucaMuccio1 and @Wenlong_Li1 ⭐️⭐️.
The special issue of @CR_AACR is now online for #AACRPan24. Here are some of the “cancer research landmarks” articles on #PancreaticCancer: (1) Cancer research landmarks on cancer associated fibroblasts (CAFs), by @BiffiGiulia & colleagues https://t.co/yFgW7cGXO0 (2) Cancer
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📢 Hot off the press! CAFs are major regulators of the immune tumor microenvironment. In our new review we dissect a fascinating aspect of this regulation: CAF-induced physical constraints controlling T cell state and localization in solid tumours
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We are looking for an enthusiastic and skilled Postdoc to study the roles of CAF metabolism in the immune-tumour microenvironment using cutting-edge spatial MS proteomics workflows and patient tissue samples. Start ASAP. https://t.co/zgXNLIbVLT
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Another interesting read from this week @Cancer_Cell! Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence:
cell.com
Watson et al. show that multiple modes of therapy-induced glioblastoma regression are associated with fibrosis, which promotes tumor cell survival. Using multi-omics analyses, they identify the...
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Classifying cancer-associated fibroblasts—The good, the bad, and the target: Cancer Cell
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Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer: Cell Reports
cell.com
Frisbie et al. demonstrate that stromal-to-tumor cell mitochondrial transfer drives ovarian cancer metastasis and clonal heterogeneity. Carcinoma-associated mesenchymal stem cells donate mitochondria...
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