Jing Yang
@Yang_J_lab
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Principal Investigator at the Guangzhou National Lab. Interested in democratizing proteomics to chemists and biologists.
北京, 中华人民共和国
Joined April 2020
Thrilled to announce that pChem is now online @nchembio. This easy-to-use computational too provides a streamlined pipeline for unbiased performance assessment of chemoproteomic probes. 1/n.
nature.com
Nature Chemical Biology - pChem is a computational tool that provides a pipeline for performance assessment of chemoproteomic probes, with the ability to score the profiling efficiency,...
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RT @Fusion_Conf: 📣Don't forget to register and submit your abstract for short talk consideration at #RedoxBio25.The chairs would love to ha….
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Congrats to Caiping, who had worked on this project for over seven years except maternity leave.
Many drugs found by chance can react w/ cysteine on target proteins. Here @NatureComms we report a large-scale chemoproteomic analysis mapping the proteome-wide ligandability of 70 drugs with diverse cys-reactive chemotypes.
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Many drugs found by chance can react w/ cysteine on target proteins. Here @NatureComms we report a large-scale chemoproteomic analysis mapping the proteome-wide ligandability of 70 drugs with diverse cys-reactive chemotypes.
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Glad to share my thoughts on emerging chemical biology strategies to interrogate cysteine-mediated redox signaling in a site-specific fashion.
pubs.rsc.org
Cysteine sulfenic acid (SOH) modifications are pivotal in redox signaling, yet establishing their causal biological roles remains challenging due to methodological limitations. Traditional approaches...
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RT @lkcmedresearch: April 2025 EXCEL Research Seminar speaker, Prof Fuchu He delivering his talk titled “π-HuB: the proteomic navigator of….
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Heard this amazing story in the Redox GRC last year😁.
Check out our paper on proton pump inhibitor activation in cells in @NatureChemistry. Congrats to first author Teresa Marker who started this project in my group and finished it with Tobias Dick (@RedoxDKFZ). More collabs between our groups @DKFZ to come!
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RT @labs_mann: China clearly sees the potential of proteomics and is about to place a gigantic bet on it; multi-billion dollar and 30 years….
nature.com
Nature - We introduce a major scientific endeavour called π-HuB (proteomic navigator of the human body), its aim being to generate and harness multimodality proteomic datasets to enhance our...
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Very excited to share our Perspective @Nature on how can proteomics help us to live long and prosper🖖#πHuB.
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Glad to see this latest showcase where pChem ( was used to demonstrate the lysine-specificity of a new bioconjugation method.
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RT @slavov_n: Welcome BayesPG, the fruit of a long & enjoyable collaboration with Alex Franks: It started with a s….
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RT @mann_ivel: Announcing 22nd SFRR-International Biennial Meeting (hosts SFRR-Europe) in Galway, Ireland 3-6 June 2025 (.
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Thrilled to catch up with many old friends and meet new friends! .Thiol-based redox regulation and signaling #GRC
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RT @Pdorrestein1: I am so excited that @em_gentry1 (@gentrylab) paper on reverse metabolomics to discover molecules is published, a project….
nature.com
Nature - A new discovery strategy, ‘reverse metabolomics’, facilitates high-throughput matching of mass spectrometry spectra in public untargeted metabolomics datasets, and a...
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RT @Picotti_Lab: It was an honor to receive the MCP Lectureship Award at the @EMBLEvents #EWCSProteomics conference. I am grateful to @ASBM….
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