Oxidative inactivation of GAPDH is a booster for reductive power. Tumor cells employ this mechanism to survive in the host and to resist therapy. Many thanks to our long-term collaborators @RalserLab, @MilsomMick & @pavlo_lutsik.

"In the Pipeline" @ScienceMagazine: Derek Lowe reflects on “Weird Little Sulfur Groups”, inspired by our new paper on protein persulfidation @nchembio.

We are looking for a new #PhD student to work on #persulfides and their role in #ferroptosis, as part of @Ferroptosis2306. #PhDposition #RedoxBiology #ChemicalBiology #DKFZ #UniHeidelberg

RT @bstockwell: Congrats to .@PrattGroup.@RedoxDKFZ.@almut_schulze.@AngeliFriedmann. for discovering the role of hydropersulfides and other….

RT @OlzmannLab: Happy to write this @CellChemBiol Spotlight with @MikeLangePhD highlighting recent exciting work from @RedoxDKFZ, @PrattGro….

News and Views @nchembio: Jon M. Fukuto discussing new insights into the cytoprotective roles of hydropersulfides: ."A radical way to avoid cell death".

RT @DKFZ: How stressed tumor cells escape cell death: Scientists at the German Cancer Research Center have now discovered a new mechanism b….

Great to see mutually confirming and complementary research on hydropersulfides as outstanding radical scavengers from @PrattGroup @J_A_C_S along with our's @RedoxDKFZ @nchembio.

All across biology, cells produce hydropersulfides (RSSH). But why? We found them to scavenge free radicals and protect biomembranes @nchembio. Many thanks to our collaborators @AngeliFriedmann @Ferroptosis2306 @almut_schulze @DrugDiscov_DKFZ @graeter_mbm.

If you want to detect protein persulfides you need to trap them first… here we share a story that started with puzzling observations and led to new insights into the behavior of alkylating agents. Thanks to @DrugDiscov_DKFZ for the nice collaboration.

N-acetylcysteine (NAC) is widely used as an "antioxidant". But do we understand what it is doing inside cells and organisms? Check out our review, by @Brandanium, @Vladi76320028 and Daria, now at @MessensLab:

Specific redox signaling needs a scaffold. Check out our new paper on the Prx2-STAT3 redox relay. @NatureComms .

Thank you, Ari, Bruno and Madia @Udelaruy for writing an insightful commentary on our recent peroxiredoxin paper.

If you are interested in the highly dynamic quaternary structure of peroxiredoxins, take a look at our new paper.