Venkat Mudiyam
@VMudiyam
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Doctoral student @MGissot lab @Pasteurlille | Alumni: @UniBonn @plasmobees @official_IBAB @VFSTR_Vignan | Enjoys 🧑🏽🔬🍲🥾🏸🏐🥏
Lille, France
Joined May 2020
Drs @be_maanasa @Vmudiyam & @Mgissot review #Toxoplasma #gondii #endodyogeny: how to make perfect daughters. #Apicomplexa #ExpansionMicroscopy #Phosphorylation #Transcription @PasteurLille @CIILofficiel @CHU_Lille @CNRS @Inserm
https://t.co/iUML0miaFw
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How does Toxoplasma gondii tachyzoites multiply so efficiently? Our review dives into the molecular choreography of endodyogeny—scaffolds, transcription factors, and cytoskeleton that enable parasite division. 👉 https://t.co/Xc642un7gY
@be_maanasa @VMudiyam @TrendsParasitol
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Thrilled to have this out! Please go checkout our work👇 on the crazy Toxo #mitoribosome. A huge thanks and 🙌 to everyone involved in the study.
Remember learning that #ribosomes are made of 1 large subunit RNA + 1 small subunit RNA? Well, some cells defy this rule, and the most extreme case is #Toxoplasma which makes its mitoribosome from >50 RNA pieces! Wanna know how? Read the next comments.
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Happy to have contributed a small part to this meaningful work!
The best way to start 2025: our latest work is out in #PLOSPathogens. It discusses ApiAP2 transcription factors and daughter cell assembly in T. gondii. A work spearheaded by @be_maanasa with the contribution of @VMudiyam
https://t.co/BdeKPQfehq📷
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Congratulations @be_maanasa 🥳🥳
Congratulations to @be_maanasa on successfully passing her PhD defense! Dr. @be_maanasa is now heading to a new adventure as a Postdoc. I wish her the best.
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Mitochondria are the powerhouse of the cell, producing essential energy for life 🏭⚙️. To synthesize the proteins for this process, mitochondria have mitoribosomes. But, how do the mitoribosomes from Alveolates assemble? 🧵 https://t.co/bxnrDmGviz
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BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
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BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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ErythroMer, designed to be stored for years and work on any blood type, could provide a critical alternative when real blood is unavailable. Learn more in this @NewsfromScience feature: https://t.co/UxUBsrfPpU
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Apicomplexan #parasite division: @MGissot &co show that the #phosphatase TgPP1 in #Toxoplasma regulates the #CellCycle & amylopectin accumulation by dephosphorylating inner membrane complex & starch-binding domain proteins #PLOSBiology
https://t.co/feywhq7Fks
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Hot off the press, congratulations, you all!! @MGissot @be_maanasa
A new study in @PLOSBiology from our lab shows the role of the PP1 phosphatase in controlling the tachyzoite cell cycle and amylopectin storage in T. gondii. Kudos to the two PhD students involved: AS Khelifa and @be_maanasa ! #PLOSBiology: https://t.co/BaGpbEzNxY
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It appears #NIAID will shutter the genome data base we all use daily. This strikes me as a significant mistake that may well endanger much of our global progress. @BSPparasitology @AS_Para @ASTMH @TrendsParasitol @AmSocParasit @parasitesrule @PiParasitology
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Engineered Toxoplasma gondii delivers intracellular proteins to neurons, including MeCP2 to the CNS of mice #NBThighlight
nature.com
Nature Microbiology - Toxoplasma gondii secretion systems can be engineered to deliver multiple large therapeutic proteins to neurons in vitro and in vivo.
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Big Nature paper this week on improved lifespan (in mice!) using an antibody to block IL11 Old mice without IL11 even look healthier 🧵
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Researchers in @LouridoLab performed the first genome-wide screen of Toxoplasma gondii in live hosts, revealing genes that are important for infection but previously undetected in cell culture experiments: https://t.co/Em4ZGCeto7
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Wow, very interesting work!😲
How does DNA damage cause apoptosis when p53 is mutated? Critical to understand treatment of many tumors. Excited that ‘DNA damage induces p53-independent apoptosis through ribosome stalling’ by Nicolaas Boon and collaborators is out: https://t.co/BUFlO8hN3C
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The second article of the JOYI 2024 series, features @plasmobees @official_ibab. In this article, she navigates the challenging transition journey to India, unanswered questions about the academic hiring process and more. 🇮🇳 Read 👉 https://t.co/eQqd0a5ayB
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Thanks to the organizers for an insightful two-day ToxoDB workshop! Excited to apply the concepts I've learned! #ToxoDB #VEuPathDB #Toxo24
We are at #toxo24 running a pre-meeting #toxodb workshop. Looking forward to two busy days working through exercises.
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@SayaliDeolankar 1 of my colleagues told me smthing whn I joined. Aftr 10 yrs, I undrstnd the value of that advice. He told, “Abhijit, b aware of 2 acad sins. 1. Not rewarding who deserves, and 2. Rewarding who doesn’t deserve”. A guide would always invest more into who puts effort.
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